Share Facebook
Crohn's Disease Forum » Treatment » Prednisone/Entocort » Do Steroids effect your mood/personality?


07-06-2013, 08:35 AM   #1
RZman
 
RZman's Avatar
 
Join Date: Mar 2013
Location: Santa Monica, California
Do Steroids effect your mood/personality?

I've been on steroids for 10 weeks. I've recently noticed that I'm getting angry over trivial matters and I experience anxiety when interacting with unfamiliar people. This is totally antithetic to my personality. I'm normally very confident, easy going and very gregarious. The only change in my life has been the steroid. Anyone else experience mood or personality changes when taking steroids?
__________________
Chron's Disease since 1978
Married 18 years
Asacol & Uceris + a few other meds
07-06-2013, 09:03 AM   #2
nogutsnoglory
Moderator
 
nogutsnoglory's Avatar
 
Join Date: Sep 2009
Location: New York

My Support Groups:
Unfortunately these drugs can have a strong impact on your mental health including personality changes, depression and irritability. Please call your doctor at once to describe your symptoms.

http://www.drugs.com/sfx/prednisone-side-effects.html
07-06-2013, 11:48 AM   #3
PsychoJane
Moderator
 
PsychoJane's Avatar
 
Join Date: Mar 2011
Location: Quebec

My Support Groups:
When I was on steroid my mother would describe me as pretty despicable. I remember I would be very edgy while on prednisone, that, along with the fact I had to accept that disease was not the best combo. Are you tapering from steroids right now or starting soon?
__________________
Diagnosed UC 1999 then refractory CD.
Past Meds: Prednisone, asacol, cyclosporine, cyclophosphamide, mp6, Humira

Currently taking: Omega-3, D-3, med-free for the time being.
~~Oh! n sorry if what I write seems strange at times, English is not my main language!~~

You'd like to chat and feel facebook would ease this point,
send me a private message and i'll do so =)
07-06-2013, 01:16 PM   #4
Dukeis
Dynastic Overlord
 
Dukeis's Avatar
 
Join Date: Sep 2012
Location: Cabot, Arkansas

My Support Groups:
That sure sounds like steriods to me. I'm usually I really easy going guy, but when I was on steriods my wife told me at one point to go live in the office in my shop because I would fly off the handle over nothing. That is the biggest reason I hate prednisone.
__________________
Crohn's Disease. Diagnosed 1992
Total Proctocolectomy with permanent Ileostomy
March 20th, 2013 N.A.H was born!
07-06-2013, 02:12 PM   #5
UnXmas
Banned
 
Join Date: Oct 2012

My Support Groups:
They changed me quite a bit. I was incredibly bored and restless, and I was awake so many more hours because prednisone caused insomnia - the extra hours and inability to concentrate on anything made me incredibly bored. Plus it gave me so much physical energy - I didn't know what to do with all the time I used to spend napping. I also had waves of euphoria that would come over me - which wasn't as good as it sounds. Despite the false euphoria, I was really miserable.

My GP prescribed me amitriptyline which cured the insomnia instantly and relaxed me enough that I could concentrate properly again and was very calm. Then further on into my course of prednisone, whilst I was already on the ami as well, I started getting feelings of great anxiousness. These have pretty much stopped now I'm off prednisone. I don't think it ever made me angry though.
07-06-2013, 06:25 PM   #6
RZman
 
RZman's Avatar
 
Join Date: Mar 2013
Location: Santa Monica, California
Thanks for the replies and sharing your experiences. I should also ad that I'm on Uceris, not Prednisone. I was beginning to wonder why I've been so skitchy lately. Now I know why..... and it helps.
07-06-2013, 06:39 PM   #7
Kev
Senior Member
 
Join Date: Jun 2006
Location: Halifax, NS, Canada

My Support Groups:
Normally, I'm kind, patient, funny and upbeat. Not moody, incredibly slow to anger, and I normally (although some might say abnormally) try to find the humour in situations.

On steroids... one minute I'd be fighting to control a rage that came out of nowhere for no reason whatsoever... the next, I'd be crying from some deep depression that really wasn't big at all. The swings are unpredictable, magnified out of all reality, and not based on any given situation. When it made you feel good, you'd feel like superman. Then, the least little thing would be your kryptonite. The worst part is lack of control. The pred is what is in control... and it drives hormones, psychology, emotional state out of whack. The only thing worse than pred is pred withdrawal... all of the down sides and none of the physical upside. Problem is.. it works. It will stop the disease, but you can't stay on it. Now, entocort might be a more viable option. I never went on it, but I've read posts of people who swear by it. But, it only works in certain circumstances.
__________________
KEV

Dx'd July, 2006
Meds: Flagyl, Cipro, Pred, AZA.. to no effect
Low Dose Naltrexone Nov 2007 - May 2014
Remicade June 17th, 2014
07-07-2013, 04:17 AM   #8
UnXmas
Banned
 
Join Date: Oct 2012

My Support Groups:
Normally, I'm kind, patient, funny and upbeat. Not moody, incredibly slow to anger, and I normally (although some might say abnormally) try to find the humour in situations.

On steroids... one minute I'd be fighting to control a rage that came out of nowhere for no reason whatsoever... the next, I'd be crying from some deep depression that really wasn't big at all. The swings are unpredictable, magnified out of all reality, and not based on any given situation. When it made you feel good, you'd feel like superman. Then, the least little thing would be your kryptonite. The worst part is lack of control. The pred is what is in control... and it drives hormones, psychology, emotional state out of whack. The only thing worse than pred is pred withdrawal... all of the down sides and none of the physical upside. Problem is.. it works. It will stop the disease, but you can't stay on it. Now, entocort might be a more viable option. I never went on it, but I've read posts of people who swear by it. But, it only works in certain circumstances.
I agree on the control issue. I really hated discovering that my mood, emotions and personality are (at least partly) determined by chemicals. I thought I should be above that somehow. It's also interesting that the only way I found to control the effects of prednisone was using another mind-altering medication. However, I had no problems at all with steroid withdrawal. I tapered pretty quickly, I had a bit of a flu-like feeling for a couple of days when I had come off it completely, but that was it. I wonder if I hadn't been taking amitriptyline by then if I would have had more mood swings when tapering.
07-07-2013, 08:11 AM   #9
Kev
Senior Member
 
Join Date: Jun 2006
Location: Halifax, NS, Canada

My Support Groups:
I don't know if the pred withdrawal was just the pred withdrawal; or it combined with the resulting major flare-ups I would have whenever I came off pred. You know? Like, it was bad enough ... losing that feeeling of.. invinciability.. then to be swallowed up by a full blown flare. I'd have fingers and toes crossed that this time, the disease wouldn't come roaring back.. but it always did. And, then it would be back on pred again, only I would have to go to a higher dose to get the same benefits... just a big viscious circle. No, more of a big downward spiral. So, there was withdrawal, combined with flare, add in fear, depression (and me and depression were pretty much total strangers before this), anxiety... and enough residual effect from the steroids to magnify those feelings.

As roller coaster rides go, I wouldn't recommend it, and I certainly wouldn't line up for it.
07-07-2013, 08:54 AM   #10
RZman
 
RZman's Avatar
 
Join Date: Mar 2013
Location: Santa Monica, California
Thanks Kev and UnX. My doctor is going to start weening me off the Uceris at the end of this month. I currently take 1 pill a day. He's going to reduce my dose by 1/2 pill a week. I'm comfortable going very slow but concerned that I may begin to flare again. I usually get ever side effect known to man so I'm not looking forward to this.

In regards to highs and lows, I definitely experience them. The Uceris gives me tons of energy. I've been working out twice a day and I believe it's helping to diminish my anxiety. On the other hand, I'm wanting to go to bed at 6:30pm and only sleeping a couple of hours. I stay awake the rest of the night. It's definitely and emotional and physical roller coaster.
07-08-2013, 02:10 PM   #11
lsgs
Senior Member
 
lsgs's Avatar
I was initially quite short tempered. It went quickly as I tapered down. However I noticed a huge huge huge mood change after coming off pred for the better. I was quite depressed on it, feel much more myself now at 2mg
__________________
Sjogren's syndrome - 2009

Presumed IBD - 2012

Cholecystectomy, liver biopsy and lymph node excision - 2015

Primary Biliary Cholangitis - 2016

Bile Reflux Gastritis - 2016
08-22-2016, 04:45 AM   #12
LANI
 
Join Date: Aug 2016
Location: Hartlepool, United Kingdom
I have been on steriods for my uc on and off for years. This year though, ive never suffered so much mentally. My relationship with my bf of over four years is pretty much on the rocks. Im absolutely vile and struggling to control my irritability. I can get a heart pounding anger over the smallest of things. Im usually really relaxed and see things for what they are but now im the oppersit. Ive been pacing the house all morning with anxiety, making stupid mistakes and just over all nasty. I look back some time later and wonder why the hell did I get so upset over that. Its really crushing me. My poor bf has been through it also. Ive lost my home with him due to my vileness, and he has no time for me. As if things werent had enough dealing with the disease. I couldnt be any lower.
08-22-2016, 02:30 PM   #13
Lizzie
Senior Member
 
Join Date: Jun 2011
Location: East Midlands

My Support Groups:
Steroids had a really different impact on me. As well as giving me lots of energy at times, they had a fabulous antidepressant effect and I felt so happy to be alive, which probably made me a nicer person than usual!
Reply

Crohn's Disease Forum » Treatment » Prednisone/Entocort » Do Steroids effect your mood/personality?
Thread Tools


All times are GMT -5. The time now is 01:20 AM.
Copyright 2006-2017 Crohnsforum.com