Share Facebook
Crohn's Disease Forum » Treatment » Methotrexate » New to Methotrexate


06-10-2014, 08:02 PM   #1
Irish86
 
Join Date: Nov 2012
Location: meriden, Connecticut

My Support Groups:
New to Methotrexate

Will start Methotrexate on Tuesday been on 6mp for 3 yrs no noticeable help. Remicade was to costly so now Doctor will try this! Was at Dr.s today I ask if I just went cold turkey and rebooted up again what would happen? This is the third time I ask this both Dr.s said you would mostly likely die in 3 months. I 'm guessing because there would be no drug protection. So has anybody been told this? What with this new drug should I expected? Been sick since 00 many drugs,many surgeries and never really got better so hope this will help! Thank you sorry for the rambling.
06-11-2014, 10:26 PM   #2
Irish86
 
Join Date: Nov 2012
Location: meriden, Connecticut

My Support Groups:
67 looks but no help and answers from the forum?
06-12-2014, 06:49 AM   #3
SupportiveMom
Forum Monitor
 
SupportiveMom's Avatar
 
Join Date: Mar 2013
Location: Toronto, Ontario

My Support Groups:
· Stoma
Did you post this in 2 places? I swore I replied. Maybe taptalk is acting up again. Let me remember what I said...

Wow what poor bedside manner from the doc! I would consider a new doc if he/she said that. Are you on anything else but Mtx?

No meds at all can potentially cause issues so don't look to get off if you don't have a backup maintenance drug to start. I tried looking for your story but can't seem to find it. History? Meds? Can you share more? Just dropping 1 med (while on others or being closely monitored by your doc) won't kill you but can send you down a path that could create a whole new set of problems.

__________________
Mom of 16 yr. girl w/Indeter.Colitis Sep. 2012(age 11) Nov.2012 Crohn's Sep. 2014 Crohn's Colitis, UC Nov 2015, Crohn's Feb. 2016

Ileostomy surgery July 2015

Current Meds: None!
Previous Meds: Humira, Remicade, Methotrexate, Cipro, Flagyl, Zofran, Cortifoam, 5-ASA suppository, Questran, Mezavant, EEN (Peptamen Jr. 1.5) by NG tube, Antibiotic Cocktail (Vancomycin, Metronidazole & Doxycycline), Simponi, Prevacid, Imuran, prednisone
ibdsupportivmom.wordpress.com ☆
06-12-2014, 07:31 PM   #4
Irish86
 
Join Date: Nov 2012
Location: meriden, Connecticut

My Support Groups:
Sorry if I did! This is the third time this year I was told this at Yale! I ask straight forward saying if I lost my job and couldn't afford my meds. What would happen to me with no meds she says 3 months tops before you die. Disease would run rampant it would be a horrible death. They said this straight face to me. Ask Doctor is this a joke or just trying to scare me they said she can't lie. I have been sick since 2000 have had take down and j-pouch put in 01! Have never got better and have had many hospital stays! Been on many meds over the years never really worked! Remicade,Humira,6 mp,Cipro,flagyl,Predsione and now Methotrexate! I think the main thing their saying is with no meds to protect to me I'm open for attack just like in 00! Back then they gave me 6 months with all the blood and weight lost! I'm starting Tuesday Methotrexate it will be the only drug on besides vitamins .
06-13-2014, 05:32 PM   #5
SupportiveMom
Forum Monitor
 
SupportiveMom's Avatar
 
Join Date: Mar 2013
Location: Toronto, Ontario

My Support Groups:
· Stoma
Well I hope Mtx does wonders for you and you never lose insurance! Let us know how the injections go. Ocean & I are old pros..happy to help where I can!

06-14-2014, 05:23 AM   #6
Irish86
 
Join Date: Nov 2012
Location: meriden, Connecticut

My Support Groups:
Thank You will be doing pills because there is a shortage of the shot. Until there is more made then will do shots
06-16-2014, 06:32 AM   #7
SupportiveMom
Forum Monitor
 
SupportiveMom's Avatar
 
Join Date: Mar 2013
Location: Toronto, Ontario

My Support Groups:
· Stoma
There is a shortage? Now I feel bad I had to throw away her extra yesterday because she is off it and I can't give it back or give it to someone. Hopefully they fix the problem soon.

06-16-2014, 06:48 AM   #8
gemling
Senior Member
 
Join Date: May 2014
Location: United Kingdom

My Support Groups:
Without knowing the ins and outs of your history, I don't think any of us could say whether your doctor is correct or not. But it does sound, from what you've said, that you seem to have pretty severe Crohns. I certainly wouldn't like to take the risk of stopping taking any medicine whatsoever if I were in your shoes, if that helps any.

I have only recently been diagnosed though, and whilst my condition was quite bad because of how long I had been undiagnosed I don't think my Crohn's has been as rampant as yours was/is.

I am on Aza and waiting to see how it works out for me. I don't think I will go down the Methotrexate route if I can help it as I'm of childbearing age and hoping to have another child once/if my Crohn's is in check. But I really hope that it the Methotrexate works for you. My mother was on it for a while for RA.
__________________
Diagnosed May 2014
Jul 2014 Blockage caused by flare up
Sept 2014 Finished 3 Weeks of EEN. Started LOFFLEX diet
Mid-Sept 2014 Another blockage
Oct 2014 Started Infliximab


Current Medications:
Infliximab Infusions (Remicade), Loading doses
Azathioprine (100mg)
Pentasa (4g)
Supplements:
Adcal-D3 (1g)
Ferrous Fumarate (420mg)
Multivitamin
06-16-2014, 06:35 PM   #9
Irish86
 
Join Date: Nov 2012
Location: meriden, Connecticut

My Support Groups:
thank you! Doctor even said this in front of my wife! I think the whole thing their saying is with no meds it will attack with fury ! Methotrexate why do you said this is this worst then all the other meds?
06-17-2014, 07:16 AM   #10
Clash
Forum Monitor
 
Clash's Avatar
 
Join Date: Apr 2012
Location: Georgia

My Support Groups:
It's not worse than any of the other meds, the above poster is referring to the fact that it is not indicated for those who plan to get pregnant as it can cause abnormalities with the fetus. Usually, if female the GI only px'ed during child bearing years if you have a note saying you are on birth control.

I think it has also been established that men must take precaution as well. I'm not sure on that but will tag Dusty as I think she had more info.

My son was on oral methotrexate with remicade and is now only on injections of methotrexate. It was originally px'ed by his GI for CD but the injections were px'ed by his rheumatologist for spondylarthropathy.

I hope the methotrexate works well for you.
__________________
Clash
Mom to
C age 19
dx March 2012 CD

CURRENT MEDS: MTX injections, Stelara


Dx May 2014: JSpA
8/2014 ileocecectomy
9/2017 G tube

PAST MEDS: remicade, oral mtx, humira
06-17-2014, 09:28 AM   #11
mgoblue3
 
mgoblue3's Avatar
 
Join Date: Jun 2014

My Support Groups:
I was on methotrexate for about 5 years, just stopped recently like within the last month. Originally we were doing the injections, but being a kid at the time I hated it and finally convinced my doctor to let me take the pills after 3-4 years. The pills were fine, started at taking 10 then moved down to 8. At first it did help my lab results alot, especially albumin levels, both as injection and pills form. However I began taking humira along with it, and eventually moved off it within the last month as we felt it had ran its' course. It's a good medication, no flare ups, only side effect for me was nausea, which would last for 24 hours after taking it (zofran helped this somewhat). Hope it works well for you and feel better soon!
07-10-2014, 05:45 AM   #12
DustyKat
Super Moderator
 
DustyKat's Avatar
 
Join Date: May 2010
Location: New South Wales, Australia
Sorry for the late reply to Clash’s tag Irish86.

Methotrexate, is as Clash has said, a drug that is definitely contraindicated for use by both males and females when planning a pregnancy as it has the ability to cause chromosomal changes. It needs to be stopped at least 3 months prior to planned conception. It is for this reason also that men and women of childbearing age that are sexually active must use some form of birth control.

Dusty. xxx
__________________
Mum of 2 kids with Crohn's.
07-10-2014, 11:05 AM   #13
Patricia56
Senior Member
 
Patricia56's Avatar
 
Join Date: Jul 2012
Location: Northern California, USA
Methotrexate seemed to help my son for several years up until his flare in December/January which was a bad one. Now he's on Remicade and MTX together.

If you situation is truly that desperate you may want to consider the allogenic transplant study. Here's a link to information about that:

http://studies.fhcrc.org/cats/

And a Medscape article on it's success:

http://www.medscape.com/viewarticle/804570
__________________
Badger, 18, CD, overall great guy
Dxd age 10, 2006 after nearly 1 year of active sx
Current CD meds: Remicade, Methotrexate and Omeprazole, Vit. D, Calcium, Folic Acid, Probiotic

Nothing I say here should be construed as medical advice. I am not a doctor. These are just my opinions.
07-11-2014, 05:16 AM   #14
Irish86
 
Join Date: Nov 2012
Location: meriden, Connecticut

My Support Groups:
Methotrexate seemed to help my son for several years up until his flare in December/January which was a bad one. Now he's on Remicade and MTX together.

If you situation is truly that desperate you may want to consider the allogenic transplant study. Here's a link to information about that:

http://studies.fhcrc.org/cats/

And a Medscape article on it's success:

http://www.medscape.com/viewarticle/804570
Not really but filled it out to see what happens. Thank You
07-15-2014, 01:05 PM   #15
Scaryman
Forum Monitor
 
Scaryman's Avatar
 
Join Date: Jul 2012
Location: Atlanta, Georgia

My Support Groups:
Irish- the fact that your on MTX alone (correct me if Im wrong) bothers me. I speak from experience. I would seriously consider another doctor and fast. Can you afford to go out of state to a leading expert on this disease? If no PM me. I commute from Georgia out of state to the leading expert. I've run into local Doctor issues and strange drug reactions. None the less private message me. I take MTX with Humira to break down the antibodies. This gives humira a 30% more powerful punch to deal with the inflammation. Hope this gives insight.
__________________
Diagnosed 2003
5-ASA- failed
Imuran-failed with a strange reaction-paralysis
Remicade- failed with infusion reaction.
Mesalamine-another failure
Entecourt - fail- no help.
currently on Methotrexate 25mg and Humira combo.
Folic Acid Supplement
Hyclosomine,Ultram,vicoden for pain as needed
Extended right Hemocolectomy 5/24/13 Univ.Of Chicago
11/7/13- small crohns ulcer at surgical site (active).
07-15-2014, 04:40 PM   #16
Irish86
 
Join Date: Nov 2012
Location: meriden, Connecticut

My Support Groups:
Irish- the fact that your on MTX alone (correct me if Im wrong) bothers me. I speak from experience. I would seriously consider another doctor and fast. Can you afford to go out of state to a leading expert on this disease? If no PM me. I commute from Georgia out of state to the leading expert. I've run into local Doctor issues and strange drug reactions. None the less private message me. I take MTX with Humira to break down the antibodies. This gives humira a 30% more powerful punch to deal with the inflammation. Hope this gives insight.
Thanks insurance won't let my go. Yes only on MTX have done humira in the past. Remicade co-pay was crazy! Had help from remi-start but only lasted a few months before co-payment nightmares. In the beginning 01 Yale want if needed to go to Cleveland clinic or Leahy in Boston stop cold to much money. Who would be the man in Ct? Yale as always been good to me. My symptoms have always been many trips and my hold time short but goes up and down. Have 3 fistulas that drain at least once a day even with the drugs
and some stomach pains. Tough no big deal. Just signed to do bone marrow transplant for Crohn's insurance most likely will not let me have it. Thank You
Reply

Crohn's Disease Forum » Treatment » Methotrexate » New to Methotrexate
Thread Tools


All times are GMT -5. The time now is 04:03 PM.
Copyright 2006-2017 Crohnsforum.com