I have been on it for 4+ years now, aswell as azathriaprine, and I can honestly say, my life is so much better for being on those two drugs.
my crohn's is pretty bad and I have multiple fistulas and strictures in my bowl, and after starting on imuran my bowl health and stools got quite a bit better, after being on azathriaprine as well as imuran, it has got a whole lot better, I no longer get pains every time I eat something, I no longer have to rush to the toilet (or dont make it in time), I no longer have liquid stools and when I go to the toilet or break wind, it does not smell like a sewage plant has backed up either.
would not be without the two drugs now.
I know about the side effects and the fact that you can catch anything that is transferable between people, but at the end of the day, if I know anyone has something that I could catch, I do not be around them for at least 2-3 days after they are well.
I have not even had a cold or anything in the whole time I have been on these drugs, and my mum and my dad have had the norovirus(if you know what that is, Im in the UK btw) and I live with them and have not caught it off them sitting in the same room as them fairly close, so the immunity lose side of things isnt as bad as you might think.
EDIT: I ment Imuran and Infliximab not the other two, in the UK they name things differently to the US