fenway1971
Sports Crohnie
I think I've posted on this before, but I'm curious if anyone also suffers from chronic coughing in the fall/winter. Mine started about 2-3 weeks ago. It's a tickle in the back of my throat that won't go away. I've had it every year since 2002 (around time of initial diagnosis) except last winter when I was on Prednisone. It's an unproductive cough but an annoying one. More I talk, more I cough. And today, with temperature dropping to 30's, I'm coughing like a madman. Chest X-ray is normal. Every year I drag myself to a doctor to get it checked out and nothing works (inhalers, nasonex, more acid reflux meds). It is driving me nuts today!!! And, I know it'll continue for months.
If anyone has this, what clears the symptoms?
Found this article and below is excerpt on IBD. So, I'm not completely insane.
http://chestjournal.chestpubs.org/content/129/1_suppl/206S.full
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Inflammatory Bowel Diseases
Pulmonary complications of inflammatory bowel disease have been well-described. One report90 in 2003 summarized the published experience of > 400 cases of pulmonary manifestations of inflammatory bowel disease. Ulcerative colitis is more likely than Crohn disease to cause respiratory complications. Ulcerative colitis is well-known to be associated with pulmonary complications including bronchitis, bronchiectasis, bronchiolitis, nodular lung lesions, and pulmonary vasculitis.91929394 These pathologic features are separate from ILD due to sulfasalazine or mesalamine that has been used to treat the primary disease.91 The data from an ongoing registry containing 33 patients with cases of ulcerative colitis or, less often, Crohn disease reported that in several cases, the correct diagnosis and the relation of pulmonary disease to inflammatory bowel disease had not been established for many years.91 In the majority of the patients (28 of 33 patients), pulmonary features followed the onset of inflammatory bowel disease and in the remainder, pulmonary manifestations preceded those of inflammatory bowel disease. Respiratory complications included subglottic stenosis, chronic bronchitis, bronchiectasis, and chronic bronchiolitis. Histologic analysis revealed varied patterns of ILD, mainly bronchiolitis obliterans with organizing pneumonia, pulmonary infiltrates and eosinophilia, and neutrophilic necrotic parenchymal nodules. Systemic corticosteroid therapy resulted in marked improvement in patients with ILD and necrotic nodules, but was not as effective in the resolution of severe airway inflammation or chronic bronchiolitis.91 An interesting finding in this study was that respiratory problems developed postcolectomy in 8 of the 28 patients. This observation stresses the importance of considering the relationship between an unexplained cough and a “treated” nonpulmonary disorder.
Crohn disease is a less well-known cause of respiratory pathology. In a series of 11 patients with Crohn disease, cough was among the presenting symptoms in six patients. Radiologic studies showed bilateral diffuse infiltrates, lung nodules, and “ground-glass” infiltrates. Lung biopsy specimens in these 11 patients revealed chronic bronchiolitis with nonnecrotizing granulomatous inflammation, acute bronchiolitis associated with a neutrophil-rich bronchopneumonia and vague granulomatous features, cellular interstitial pneumonia with rare giant cells, and organizing pneumonia with focal granulomatous features. Four of the patients were receiving therapy with mesalamine, a known cause of pulmonary toxicity.95 This publication also identified descriptions in the literature of another 14 patients with similar pulmonary findings. The variable histologic appearances in these 25 patients were similar to those encountered in patients with ulcerative colitis. A prospective, controlled study of 23 patients with ulcerative colitis, 13 patients with Crohn disease, and 14 control subjects observed pulmonary function abnormality in 21 of 36 patients, whereas HRCT scanning demonstrated air-trapping, fibrosis, emphysema, bronchiectasis, and alveolitis in 19 patients. Even though nearly 80% of the patients with respiratory involvement had active bowel disease, one third of the patients with pulmonary function abnormality and 42% of the patients with radiologic abnormalities had no respiratory symptoms.96 Many of the drugs used to treat inflammatory bowel diseases are known to cause cough by affecting the respiratory system.9095 In addition to inflammatory bowel disease, chronic cough has also been reported as the presenting manifestation of celiac disease.67
If anyone has this, what clears the symptoms?
Found this article and below is excerpt on IBD. So, I'm not completely insane.
http://chestjournal.chestpubs.org/content/129/1_suppl/206S.full
*************************
Inflammatory Bowel Diseases
Pulmonary complications of inflammatory bowel disease have been well-described. One report90 in 2003 summarized the published experience of > 400 cases of pulmonary manifestations of inflammatory bowel disease. Ulcerative colitis is more likely than Crohn disease to cause respiratory complications. Ulcerative colitis is well-known to be associated with pulmonary complications including bronchitis, bronchiectasis, bronchiolitis, nodular lung lesions, and pulmonary vasculitis.91929394 These pathologic features are separate from ILD due to sulfasalazine or mesalamine that has been used to treat the primary disease.91 The data from an ongoing registry containing 33 patients with cases of ulcerative colitis or, less often, Crohn disease reported that in several cases, the correct diagnosis and the relation of pulmonary disease to inflammatory bowel disease had not been established for many years.91 In the majority of the patients (28 of 33 patients), pulmonary features followed the onset of inflammatory bowel disease and in the remainder, pulmonary manifestations preceded those of inflammatory bowel disease. Respiratory complications included subglottic stenosis, chronic bronchitis, bronchiectasis, and chronic bronchiolitis. Histologic analysis revealed varied patterns of ILD, mainly bronchiolitis obliterans with organizing pneumonia, pulmonary infiltrates and eosinophilia, and neutrophilic necrotic parenchymal nodules. Systemic corticosteroid therapy resulted in marked improvement in patients with ILD and necrotic nodules, but was not as effective in the resolution of severe airway inflammation or chronic bronchiolitis.91 An interesting finding in this study was that respiratory problems developed postcolectomy in 8 of the 28 patients. This observation stresses the importance of considering the relationship between an unexplained cough and a “treated” nonpulmonary disorder.
Crohn disease is a less well-known cause of respiratory pathology. In a series of 11 patients with Crohn disease, cough was among the presenting symptoms in six patients. Radiologic studies showed bilateral diffuse infiltrates, lung nodules, and “ground-glass” infiltrates. Lung biopsy specimens in these 11 patients revealed chronic bronchiolitis with nonnecrotizing granulomatous inflammation, acute bronchiolitis associated with a neutrophil-rich bronchopneumonia and vague granulomatous features, cellular interstitial pneumonia with rare giant cells, and organizing pneumonia with focal granulomatous features. Four of the patients were receiving therapy with mesalamine, a known cause of pulmonary toxicity.95 This publication also identified descriptions in the literature of another 14 patients with similar pulmonary findings. The variable histologic appearances in these 25 patients were similar to those encountered in patients with ulcerative colitis. A prospective, controlled study of 23 patients with ulcerative colitis, 13 patients with Crohn disease, and 14 control subjects observed pulmonary function abnormality in 21 of 36 patients, whereas HRCT scanning demonstrated air-trapping, fibrosis, emphysema, bronchiectasis, and alveolitis in 19 patients. Even though nearly 80% of the patients with respiratory involvement had active bowel disease, one third of the patients with pulmonary function abnormality and 42% of the patients with radiologic abnormalities had no respiratory symptoms.96 Many of the drugs used to treat inflammatory bowel diseases are known to cause cough by affecting the respiratory system.9095 In addition to inflammatory bowel disease, chronic cough has also been reported as the presenting manifestation of celiac disease.67