Very interesting article:
Dig Liver Dis. 2016 Aug 5. pii: S1590-8658(16)30546-1. doi: 10.1016/j.dld.2016.07.036. [Epub ahead of print]
Occupational risk for Crohn's disease: A two-center study.
Liu S1, Ding J1, Wang M1, Wang G2, Wu X2, Feng M1, Song P1, Ren J3, Guan W4.
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Abstract
BACKGROUND:
Occupational factors have been suggested as possible elements in the etiology of Crohn's disease, although evidences have not been fully obtained.
AIMS:
This study is to investigate possible associations between occupation and development of Crohn's disease.
METHODS:
This prospective study was carried out in two major hospitals during January 2010 and December 2014. Demographic and clinical data were collected for the calculation of standard incidence ratios and 95% confidence intervals by occupation.
RESULTS:
A total of 401 patients with Crohn's disease were recruited into this study. Participants were distributed into 8 major occupational groups, among which "professionists" (17.7%), "service and sales" (18.7%) and "unclassified individuals" (mainly students) (20.2%) took up the most proportions. Increased standard incidence ratios were found in "service and sales" (2.526±0.135, 95% CI: 1.939-3.290), "professionists" (4.216±0.142, 95% CI: 3.194-5.565), and most significantly, in "administrative staffs" (5.476±0.170, 95% CI: 3.926-7.639). In contrast, decreased standard incidence ratios for Crohn's disease were observed in the category of "workers in agriculture, forestry, animal husbandry, fishery and water conservancy" (0.088±0.146, 95% CIs: 0.066-0.117).
CONCLUSION:
Occupational elements are implicated in the likelihood of development of Crohn's disease.