kiny
Well-known member
AIEC, Crohn's Disease, Adherent-invasive Escherichia coli
1988
Adhesive Escherichia coli in inflammatory bowel disease and infective diarrhoea.
Burke DA, Axon AT.
Leeds, UK
http://www.ncbi.nlm.nih.gov/pubmed/3044496
1989
Epithelial cell invasion: an overlooked property of enteropathogenic Escherichia coli (EPEC) associated with the EPEC adherence factor.
Donnenberg MS, Donohue-Rolfe A, Keusch GT.
Massachusetts, USA
http://jid.oxfordjournals.org/content/160/3/452.long
1993
An immunocytochemical search for infectious agents in Crohn's disease.
Cartun RW, Van Kruiningen HJ, Pedersen CA, Berman MM.
Connecticut, USA
http://www.ncbi.nlm.nih.gov/pubmed/8483893
1999
Invasive ability of an Escherichia coli strain isolated from the ileal mucosa of a patient with Crohn's disease.
Jerome Boudeau, Anne-Lise Glasser, Estelle Masseret, Bernard Joly, and Arlette Darfeuille-Michaud
Clermont-Ferrand, France
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC96770/
2001
Adherent Invasive Escherichia coli Strains from Patients with Crohn's Disease Survive and Replicate within Macrophages without Inducing Host Cell Death
Glasser AL, Boudeau J, Barnich N, Perruchot MH, Colombel JF, Darfeuille-Michaud A.
Clermont-Ferrand, France
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC98666/pdf/ii005529.pdf
2003
Regulatory and functional co-operation of flagella and type 1 pili in adhesive and invasive abilities of AIEC strain LF82 isolated from a patient with Crohn's disease.
Barnich N, Boudeau J, Claret L, Darfeuille-Michaud A.
Clermont-Ferrand, France.
http://onlinelibrary.wiley.com/doi/...ionid=5D6870F31311E95D136F68ACA0D75BBB.d04t03
2004
High prevalence of adherent-invasive Escherichia coli associated with ileal mucosa in Crohn's disease.
Darfeuille-Michaud A, Boudeau J, Bulois P, Neut C, Glasser AL, Barnich N, Bringer MA, Swidsinski A, Beaugerie L, Colombel JF.
Clermont-Ferrand, France
http://www.gastrojournal.org/articl...r=http://www.ncbi.nlm.nih.gov/pubmed/15300573
2005
HtrA Stress Protein Is Involved in Intramacrophagic Replication of Adherent and Invasive Escherichia coli Strain LF82 Isolated from a Patient with Crohn's Disease
Marie-Agnès Bringer,1 Nicolas Barnich,1 Anne-Lise Glasser,1 Olivier Bardot,2 and Arlette Darfeuille-Michaud1
Clermont-Ferrand, France
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC546957/pdf/0770-04.pdf
2006
The Crohn's disease-associated adherent-invasive Escherichia coli strain LF82 replicates in mature phagolysosomes within J774 macrophages.
Marie-Agnès Bringer, Anne-Lise Glasser, Ching-Hsuan Tung, Stéphane Méresse, Arlette Darfeuille-Michaud
Clermont-Ferrand, France
http://onlinelibrary.wiley.com/doi/10.1111/j.1462-5822.2005.00639.x/abstract
Familial expression of anti-Escherichia coli outer membrane porin C in relatives of patients with Crohn's disease.
Mei L, Targan SR, Landers CJ, Dutridge D, Ippoliti A, Vasiliauskas EA, Papadakis KA, Fleshner PR, Rotter JI, Yang H.
http://www.gastrojournal.org/article/S0016-5085(06)00275-7/fulltext#section15
2007
Culture independent analysis of ileal mucosa reveals a selective increase in invasive Escherichia coli of novel phylogeny relative to depletion of Clostridiales in Crohn's disease involving the ileum.
Baumgart M, Dogan B, Rishniw M, Weitzman G, Bosworth B, Yantiss R, Orsi RH, Wiedmann M, McDonough P, Kim SG, Berg D, Schukken Y, Scherl E, Simpson KW.
Ithaca, USA
http://www.nature.com/ismej/journal/v1/n5/full/ismej200752a.html
OmpC and the sigma(E) regulatory pathway are involved in adhesion and invasion of the Crohn's disease-associated Escherichia coli strain LF82.
Rolhion N, Carvalho FA, Darfeuille-Michaud A.
Clermont-Ferrand, France.
http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2958.2007.05638.x/abstract
Adherent-invasive Escherichia coli isolated from Crohn's disease patients induce granulomas in vitro.
Meconi S, Vercellone A, Levillain F, Payré B, Al Saati T, Capilla F, Desreumaux P, Darfeuille-Michaud A, Altare F.
Toulouse, France
http://onlinelibrary.wiley.com/doi/10.1111/j.1462-5822.2006.00868.x/abstract
CEACAM6 acts as a receptor for adherent-invasive E. coli, supporting ileal mucosa colonization in Crohn disease
Nicolas Barnich,Frédéric A. Carvalho, Anne-Lise Glasser, Claude Darcha, Peter Jantscheff, Matthieu Allez,5 Harald Peeters, Gilles Bommelaer, Pierre Desreumaux, Jean-Frédéric Colombel, and Arlette Darfeuille-Michaud
Clermont-Ferrand, France
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1868786/pdf/JCI0730504.pdf
CARD15 variants determine a disturbed early response of monocytes to adherent-invasive Escherichia coli strain LF82 in Crohn's disease.
Peeters H, Bogaert S, Laukens D, Rottiers P, De Keyser F, Darfeuille-Michaud A, Glasser AL, Elewaut D, De Vos M
Ghent, Belgium
http://onlinelibrary.wiley.com/doi/10.1111/j.1744-313X.2007.00670.x/abstract
The oxidoreductase DsbA plays a key role in the ability of the Crohn's disease-associated adherent-invasive Escherichia coli strain LF82 to resist macrophage killing
Bringer MA, Rolhion N, Glasser AL, Darfeuille-Michaud A.
Clermont, France
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1913465/pdf/0233-07.pdf
The flagellar sigma factor FliA regulates adhesion and invasion of Crohn disease-associated Escherichia coli via a cyclic dimeric GMP-dependent pathway.
Claret L, Miquel S, Vieille N, Ryjenkov DA, Gomelsky M, Darfeuille-Michaud A.
Clermont-Ferrand, France
http://www.jbc.org/content/282/46/33275.long
The effects of low-shear stress on Adherent-invasive Escherichia coli
Christopher A. Allen, David W. Niesel, Alfredo G. Torres
Texas, USA
http://onlinelibrary.wiley.com/doi/10.1111/j.1462-2920.2008.01567.x/abstract
Escherichia coli isolated from a Crohn's disease patient adheres, invades, and induces inflammatory responses in polarized intestinal epithelial cells.
Eaves-Pyles T, Allen CA, Taormina J, Swidsinski A, Tutt CB, Jezek GE, Islas-Islas M, Torres AG.
Texas, USA
http://www.sciencedirect.com/science/article/pii/S1438422107001233
2008
Crohn's disease-associated Escherichia coli LF82 aggravates colitis in injured mouse colon via signaling by flagellin.
Carvalho FA, Barnich N, Sauvanet P, Darcha C, Gelot A, Darfeuille-Michaud A
Clermont-Ferrand, France.
Crohn's disease-associated Escherichia coli LF82 aggravates colitis in injured mouse colon via signaling by flagellin
2009
Enterovirulent E. coli in inflammatory and noninflammatory bowel diseases.
Curová K, Kmetová M, Sabol M, Gombosová L, Lazúrová I, Siegfried L.
Kosice, Slovakia
http://link.springer.com/article/10.1007/s12223-009-0012-y
Molecular diversity of Escherichia coli in the human gut: new ecological evidence supporting the role of adherent-invasive E. coli (AIEC) in Crohn's disease.
Martinez-Medina M, Aldeguer X, Lopez-Siles M, González-Huix F, López-Oliu C, Dahbi G, Blanco JE, Blanco J, Garcia-Gil LJ, Darfeuille-Michaud A.
Girona, Spain
http://www.ncbi.nlm.nih.gov/pubmed/19235912
Adherent-invasive Escherichia coli, strain LF82 disrupts apical junctional complexes in polarized epithelia.
Eytan Wine, Juan C Ossa, Scott D Gray-Owen, and Philip M Sherman
Toronto, Canada
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2741472/pdf/1471-2180-9-180.pdf
Biofilm formation as a novel phenotypic feature of adherent-invasive Escherichia coli (AIEC).
Martinez-Medina M, Naves P, Blanco J, Aldeguer X, Blanco JE, Blanco M, Ponte C, Soriano F, Darfeuille-Michaud A, Garcia-Gil LJ
Girona, Spain
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2759958/
Crohn's disease adherent-invasive Escherichia coli colonize and induce strong gut inflammation in transgenic mice expressing human CEACAM.
Carvalho FA, Barnich N, Sivignon A, Darcha C, Chan CH, Stanners CP, Darfeuille-Michaud A.
Clermont-Ferrand, France
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757893/
Phylogenetic analysis of inflammatory bowel disease associated Escherichia coli and the fimH virulence determinant.
Sepehri S, Kotlowski R, Bernstein CN, Krause DO.
Manitoba, Canada
http://www.ncbi.nlm.nih.gov/pubmed/19462430
Similarity and divergence among adherent-invasive Escherichia coli and extraintestinal pathogenic E. coli strains.
Martinez-Medina M, Mora A, Blanco M, López C, Alonso MP, Bonacorsi S, Nicolas-Chanoine MH, Darfeuille-Michaud A, Garcia-Gil J, Blanco J.
Girona, Spain
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2786640/
Crohn's disease-associated adherent-invasive E. coli are selectively favoured by impaired autophagy to replicate intracellularly.
Lapaquette P, Glasser AL, Huett A, Xavier RJ, Darfeuille-Michaud A
Clermont-Ferrand, France
http://onlinelibrary.wiley.com/doi/10.1111/j.1462-5822.2009.01381.x/abstract
Adherent-invasive Escherichia coli target the epithelial barrier
Wine E, Ossa JC, Gray-Owen SD, Sherman PM.
Alberta, Canada
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023584/
2010
Role of decreased levels of Fis histone-like protein in Crohn's disease-associated adherent invasive Escherichia coli LF82 bacteria interacting with intestinal epithelial cells.
Miquel S, Claret L, Bonnet R, Dorboz I, Barnich N, Darfeuille-Michaud A.
Clermont-Ferrand, France
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2838056/
Abnormal CEACAM6 expression in Crohn disease patients favors gut colonization and inflammation by adherent-invasive E. coli.
Barnich N, Darfeuille-Michaud A.
Clermont-Ferrand, France
[URL="http://www.landesbioscience.com/journals/virulence/article/11510/?nocache=895750331"]http://www.landesbioscience.com/journals/virulence/article/11510/?nocache=895750331[/URL]
Complete genome sequence of Crohn's disease-associated adherent-invasive E. coli strain LF82.
Miquel S, Peyretaillade E, Claret L, de Vallée A, Dossat C, Vacherie B, Zineb el H, Segurens B, Barbe V, Sauvanet P, Neut C, Colombel JF, Medigue C, Mojica FJ, Peyret P, Bonnet R, Darfeuille-Michaud A.
Clermont-Ferrand, France
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2941450/
Abnormally expressed ER stress response chaperone Gp96 in CD favours adherent-invasive Escherichia coli invasion.
Rolhion N, Barnich N, Bringer MA, Glasser AL, Ranc J, Hébuterne X, Hofman P, Darfeuille-Michaud A.
Clermont-Ferrand, France
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2976078/
Genome sequence of adherent-invasive Escherichia coli and comparative genomic analysis with other E. coli pathotypes.
Nash JH, Villegas A, Kropinski AM, Aguilar-Valenzuela R, Konczy P, Mascarenhas M, Ziebell K, Torres AG, Karmali MA, Coombes BK.
Ontario, Canada
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091784/
Role of meprins to protect ileal mucosa of Crohn's disease patients from colonization by adherent-invasive E. coli.
Vazeille E, Bringer MA, Gardarin A, Chambon C, Becker-Pauly C, Pender SL, Jakob C, Müller S, Lottaz D, Darfeuille-Michaud A.
Clermont-Ferrand, France
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116889/
Translocation of Crohn's disease Escherichia coli across M-cells: contrasting effects of soluble plant fibres and emulsifiers.
Roberts CL, Keita AV, Duncan SH, O'Kennedy N, Söderholm JD, Rhodes JM, Campbell BJ
Liverpool, UK.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2976079/
2011
Crohn disease--associated adherent-invasive E. coli bacteria target mouse and human Peyer's patches via long polar fimbriae.
Chassaing B, Rolhion N, de Vallée A, Salim SY, Prorok-Hamon M, Neut C, Campbell BJ, Söderholm JD, Hugot JP, Colombel JF, Darfeuille-Michaud A.
Clermont-Ferrand, France
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049390/
A role for the RNA chaperone Hfq in controlling adherent-invasive Escherichia coli colonization and virulence.
Karina T. Simonsen, Gorm Nielsen, Janni Vester Bjerrum, Thomas Kruse, Birgitte H. Kallipolitis, Jakob Møller-Jensen
Odense, Denmark
http://www.plosone.org/article/info:doi/10.1371/journal.pone.0016387
The endoplasmic reticulum stress response chaperone: Gp96, a host receptor for Crohn disease-associated adherent-invasive Escherichia coli.
Rolhion N, Hofman P, Darfeuille-Michaud A.
Auvergne, France
http://www.landesbioscience.com/journals/gutmicrobes/article/15725/?nocache=1131403153
Analysis of Escherichia coli isolated from patients affected by Crohn's disease.
Raso T, Crivellaro S, Chirillo MG, Pais P, Gaia E, Savoia D.
Turin, Italy
http://link.springer.com/article/10.1007/s00284-011-9947-8
Adherent-invasive Escherichia coli phenotype displayed by intestinal pathogenic E. coli strains from cats, dogs, and swine.
Martinez-Medina M, Garcia-Gil J, Barnich N, Wieler LH, Ewers C.
Girona, Spain
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3165260/
Crohn disease-associated Escherichia coli promote gastrointestinal inflammatory disorders by activation of HIF-dependent responses.
Mimouna S, Gonçalvès D, Barnich N, Darfeuille-Michaud A, Hofman P, Vouret-Craviari V.
Nice, France
http://www.landesbioscience.com/journals/gutmicrobes/article/18771/?nocache=1310052539
Ex vivo intestinal adhesion of Escherichia coli LF82 in Crohn's disease.
Jensen SR, Fink LN, Nielsen OH, Brynskov J, Brix S.
Lyngby, Denmark
http://www.sciencedirect.com/science/article/pii/S0882401011001604
Adherent-invasive Escherichia coli induce claudin-2 expression and barrier defect in CEABAC10 mice and Crohn's disease patients.
Denizot J, Sivignon A, Barreau F, Darcha C, Chan HF, Stanners CP, Hofman P, Darfeuille-Michaud A, Barnich N.
Clermont-Ferrand, France
http://www.ncbi.nlm.nih.gov/pubmed/21688348
Role of meprins to protect ileal mucosa of Crohn's disease patients from colonization by adherent-invasive E. coli.
Vazeille E, Bringer MA, Gardarin A, Chambon C, Becker-Pauly C, Pender SL, Jakob C, Müller S, Lottaz D, Darfeuille-Michaud A.
Clermont-Ferrand, France
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116889/pdf/pone.0021199.pdf
Characterization of adherent-invasive Escherichia coli isolated from pediatric patients with inflammatory bowel disease.
Negroni A, Costanzo M, Vitali R, Superti F, Bertuccini L, Tinari A, Minelli F, Di Nardo G, Nuti F, Pierdomenico M, Cucchiara S, Stronati L.
Rome, Italy
http://www.ncbi.nlm.nih.gov/pubmed/21994005
Replication of Crohn's disease-associated AIEC within macrophages is dependent on TNF-α secretion.
Bringer MA, Billard E, Glasser AL, Colombel JF, Darfeuille-Michaud A.
Clermont-Ferrand, France
http://www.nature.com/labinvest/journal/v92/n3/full/labinvest2011156a.html
Crohn disease-associated Escherichia coli promote gastrointestinal inflammatory disorders by activation of HIF-dependent responses.
Mimouna S, Gonçalvès D, Barnich N, Darfeuille-Michaud A, Hofman P, Vouret-Craviari V.
Nice, France
http://www.landesbioscience.com/journals/gutmicrobes/article/18771/?nocache=1026489613
2012
Defects in autophagy favour adherent-invasive Escherichia coli persistence within macrophages leading to increased pro-inflammatory response.
Lapaquette P, Bringer MA, Darfeuille-Michaud A.
Clermont-Ferrand, France
http://onlinelibrary.wiley.com/doi/...ionid=4F9FD0741445725A8A6859EC750D6ABB.d01t02
AIEC colonization and pathogenicity: influence of previous antibiotic treatment and preexisting inflammation.
Drouet M, Vignal C, Singer E, Djouina M, Dubreuil L, Cortot A, Desreumaux P, Neut C.
Lille, France
http://www.ncbi.nlm.nih.gov/pubmed/22344932
A potential role of Escherichia coli pathobionts in the pathogenesis of pediatric inflammatory bowel disease.
Schippa S, Iebba V, Totino V, Santangelo F, Lepanto M, Alessandri C, Nuti F, Viola F, Di Nardo G, Cucchiara S, Longhi C, Conte MP.
Rome, Italy
http://www.nrcresearchpress.com/doi/abs/10.1139/w2012-007?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed&
Multidrug resistance is common in Escherichia coli associated with ileal Crohn's disease
Dogan B, Scherl E, Bosworth B, Yantiss R, Altier C, McDonough PL, Jiang ZD, Dupont HL, Garneau P, Harel J, Rishniw M, Simpson KW.
New York, USA
http://www.ncbi.nlm.nih.gov/pubmed/22508665
Infection strategies of enteric pathogenic Escherichia coli.
Clements A, Young JC, Constantinou N, Frankel G.
London, UK
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3370951/pdf/gmic-3-71.pdf
Bile salts induce long polar fimbriae expression favouring Crohn's disease-associated adherent-invasive Escherichia coli interaction with Peyer's patches.
Chassaing B, Etienne-Mesmin L, Bonnet R, Darfeuille-Michaud A.
Clermont-Ferrand, France
http://onlinelibrary.wiley.com/doi/10.1111/j.1462-2920.2012.02824.x/abstract
Adherent-invasive Escherichia coli blocks interferon-γ-induced signal transducer and activator of transcription (STAT)-1 in human intestinal epithelial cells.
Ossa JC, Ho NK, Wine E, Leung N, Gray-Owen SD, Sherman PM.
Toronto, ON, Canada
http://onlinelibrary.wiley.com/doi/10.1111/cmi.12048/abstract
The σE pathway is involved in biofilm formation by Crohn's disease-associated adherent-invasive Escherichia coli.
Chassaing B, Darfeuille-Michaud A.
Clermont-Ferrand, France
http://jb.asm.org/content/195/1/76.long
Crohn's disease-associated adherent-invasive Escherichia coli adhesion is enhanced by exposure to the ubiquitous dietary polysaccharide maltodextrin.
Nickerson KP, McDonald C.
Ohio, USA
http://www.plosone.org/article/info:doi/10.1371/journal.pone.0052132
Subversion of Autophagy in Adherent Invasive Escherichia coli-Infected Neutrophils Induces Inflammation and Cell Death
Abderrahman Chargui, Annabelle Cesaro, Sanda Mimouna, Mohamed Fareh, Patrick Brest, Philippe Naquet, Arlette Darfeuille-Michaud,Xavier Hébuterne, Baharia Mograbi, Valérie Vouret-Craviari, Paul Hofman
Nice, France
http://www.plosone.org/article/info:doi/10.1371/journal.pone.0051727
2013
Western diet induces dysbiosis with increased E coli in CEABAC10 mice, alters host barrier function favouring AIEC colonisation.
Martinez-Medina M, Denizot J, Dreux N, Robin F, Billard E, Bonnet R, Darfeuille-Michaud A, Barnich N.
Clermont-Ferrand, France
http://www.ncbi.nlm.nih.gov/pubmed/23598352
Crohn's disease AIEC invade macrophages by suppressing NFkB signaling
Khalidur Rahman, Maiko Sasaki, Jan-Michael A. Klapproth
Persistent infection with Crohn’s disease-associated adherent-invasive Escherichia coli leads to chronic inflammation and intestinal fibrosis
Cherrie-Lee N. Small, Sarah A. Reid-Yu, Joseph B. McPhee & Brian K. Coombes
Ontario, Canada
http://www.nature.com/ncomms/2013/130610/ncomms2957/full/ncomms2957.html
Serological markers predict inflammatory bowel disease years before the diagnosis.
van Schaik FD, Oldenburg B, Hart AR, Siersema PD, Lindgren S, Grip O, Teucher B, Kaaks R, Bergmann MM, Boeing H, Carbonnel F, Jantchou P, Boutron-Ruault MC, Tjønneland A, Olsen A, Crowe FL, Peeters PH, van Oijen MG, Bueno-de-Mesquita HB
Utrecht, The Netherlands
http://www.ncbi.nlm.nih.gov/pubmed/22842615
AIEC (LF82) are potently pro-inflammatory for monocytes, but not intestinal macrophages, in patients with crohn's disease.
Colonic mucosa-associated diffusely adherent afaC+ Escherichia coli expressing lpfA and pks are increased in inflammatory bowel disease and colon cancer
Maelle Prorok-Hamon, Melissa K Friswell, Abdullah Alswied, Carol L Roberts,Fei Song, Paul K Flanagan, Paul Knight, Caroline Codling, Julian R Marchesi, Craig Winstanley, Neil Hall, Jonathan M Rhodes, Barry J Campbell
Liverpool, UK
http://gut.bmj.com/content/early/2013/07/10/gutjnl-2013-304739.full.pdf+html
Increased S-Nitrosylation and Proteasomal Degradation of Caspase-3 during Infection Contribute to the Persistence of Adherent Invasive Escherichia coli (AIEC) in Immune Cells
Karl A. Dunne, Amr Allam, Anne McIntosh, Stephanie A. Houston, Vuk Cerovic,
Carl S. Goodyear, Andrew J. Roe, Scott A. Beatson, Simon W. Milling, Daniel Walker, Daniel M. Wall
Glasgow, UK
Queensland, Australia
http://www.plosone.org/article/info:doi/10.1371/journal.pone.0068386
Crohn's Disease-associated Adherent Invasive Escherichia coli Affect Levels of microRNAs in Intestinal Epithelial Cells to Reduce Autophagy
Hang Thi Thu Nguyen, Guillaume Dalmasso, Stefan Müller, Jessica Carrière, Frank Seibold, Arlette Darfeuille-Michaud
Clermont-Ferrand, France
http://www.gastrojournal.org/article/S0016-5085(13)01495-9/abstract
1988
Adhesive Escherichia coli in inflammatory bowel disease and infective diarrhoea.
Burke DA, Axon AT.
Leeds, UK
http://www.ncbi.nlm.nih.gov/pubmed/3044496
1989
Epithelial cell invasion: an overlooked property of enteropathogenic Escherichia coli (EPEC) associated with the EPEC adherence factor.
Donnenberg MS, Donohue-Rolfe A, Keusch GT.
Massachusetts, USA
http://jid.oxfordjournals.org/content/160/3/452.long
1993
An immunocytochemical search for infectious agents in Crohn's disease.
Cartun RW, Van Kruiningen HJ, Pedersen CA, Berman MM.
Connecticut, USA
http://www.ncbi.nlm.nih.gov/pubmed/8483893
1999
Invasive ability of an Escherichia coli strain isolated from the ileal mucosa of a patient with Crohn's disease.
Jerome Boudeau, Anne-Lise Glasser, Estelle Masseret, Bernard Joly, and Arlette Darfeuille-Michaud
Clermont-Ferrand, France
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC96770/
2001
Adherent Invasive Escherichia coli Strains from Patients with Crohn's Disease Survive and Replicate within Macrophages without Inducing Host Cell Death
Glasser AL, Boudeau J, Barnich N, Perruchot MH, Colombel JF, Darfeuille-Michaud A.
Clermont-Ferrand, France
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC98666/pdf/ii005529.pdf
2003
Regulatory and functional co-operation of flagella and type 1 pili in adhesive and invasive abilities of AIEC strain LF82 isolated from a patient with Crohn's disease.
Barnich N, Boudeau J, Claret L, Darfeuille-Michaud A.
Clermont-Ferrand, France.
http://onlinelibrary.wiley.com/doi/...ionid=5D6870F31311E95D136F68ACA0D75BBB.d04t03
2004
High prevalence of adherent-invasive Escherichia coli associated with ileal mucosa in Crohn's disease.
Darfeuille-Michaud A, Boudeau J, Bulois P, Neut C, Glasser AL, Barnich N, Bringer MA, Swidsinski A, Beaugerie L, Colombel JF.
Clermont-Ferrand, France
http://www.gastrojournal.org/articl...r=http://www.ncbi.nlm.nih.gov/pubmed/15300573
2005
HtrA Stress Protein Is Involved in Intramacrophagic Replication of Adherent and Invasive Escherichia coli Strain LF82 Isolated from a Patient with Crohn's Disease
Marie-Agnès Bringer,1 Nicolas Barnich,1 Anne-Lise Glasser,1 Olivier Bardot,2 and Arlette Darfeuille-Michaud1
Clermont-Ferrand, France
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC546957/pdf/0770-04.pdf
2006
The Crohn's disease-associated adherent-invasive Escherichia coli strain LF82 replicates in mature phagolysosomes within J774 macrophages.
Marie-Agnès Bringer, Anne-Lise Glasser, Ching-Hsuan Tung, Stéphane Méresse, Arlette Darfeuille-Michaud
Clermont-Ferrand, France
http://onlinelibrary.wiley.com/doi/10.1111/j.1462-5822.2005.00639.x/abstract
Familial expression of anti-Escherichia coli outer membrane porin C in relatives of patients with Crohn's disease.
Mei L, Targan SR, Landers CJ, Dutridge D, Ippoliti A, Vasiliauskas EA, Papadakis KA, Fleshner PR, Rotter JI, Yang H.
http://www.gastrojournal.org/article/S0016-5085(06)00275-7/fulltext#section15
2007
Culture independent analysis of ileal mucosa reveals a selective increase in invasive Escherichia coli of novel phylogeny relative to depletion of Clostridiales in Crohn's disease involving the ileum.
Baumgart M, Dogan B, Rishniw M, Weitzman G, Bosworth B, Yantiss R, Orsi RH, Wiedmann M, McDonough P, Kim SG, Berg D, Schukken Y, Scherl E, Simpson KW.
Ithaca, USA
http://www.nature.com/ismej/journal/v1/n5/full/ismej200752a.html
OmpC and the sigma(E) regulatory pathway are involved in adhesion and invasion of the Crohn's disease-associated Escherichia coli strain LF82.
Rolhion N, Carvalho FA, Darfeuille-Michaud A.
Clermont-Ferrand, France.
http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2958.2007.05638.x/abstract
Adherent-invasive Escherichia coli isolated from Crohn's disease patients induce granulomas in vitro.
Meconi S, Vercellone A, Levillain F, Payré B, Al Saati T, Capilla F, Desreumaux P, Darfeuille-Michaud A, Altare F.
Toulouse, France
http://onlinelibrary.wiley.com/doi/10.1111/j.1462-5822.2006.00868.x/abstract
CEACAM6 acts as a receptor for adherent-invasive E. coli, supporting ileal mucosa colonization in Crohn disease
Nicolas Barnich,Frédéric A. Carvalho, Anne-Lise Glasser, Claude Darcha, Peter Jantscheff, Matthieu Allez,5 Harald Peeters, Gilles Bommelaer, Pierre Desreumaux, Jean-Frédéric Colombel, and Arlette Darfeuille-Michaud
Clermont-Ferrand, France
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1868786/pdf/JCI0730504.pdf
CARD15 variants determine a disturbed early response of monocytes to adherent-invasive Escherichia coli strain LF82 in Crohn's disease.
Peeters H, Bogaert S, Laukens D, Rottiers P, De Keyser F, Darfeuille-Michaud A, Glasser AL, Elewaut D, De Vos M
Ghent, Belgium
http://onlinelibrary.wiley.com/doi/10.1111/j.1744-313X.2007.00670.x/abstract
The oxidoreductase DsbA plays a key role in the ability of the Crohn's disease-associated adherent-invasive Escherichia coli strain LF82 to resist macrophage killing
Bringer MA, Rolhion N, Glasser AL, Darfeuille-Michaud A.
Clermont, France
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1913465/pdf/0233-07.pdf
The flagellar sigma factor FliA regulates adhesion and invasion of Crohn disease-associated Escherichia coli via a cyclic dimeric GMP-dependent pathway.
Claret L, Miquel S, Vieille N, Ryjenkov DA, Gomelsky M, Darfeuille-Michaud A.
Clermont-Ferrand, France
http://www.jbc.org/content/282/46/33275.long
The effects of low-shear stress on Adherent-invasive Escherichia coli
Christopher A. Allen, David W. Niesel, Alfredo G. Torres
Texas, USA
http://onlinelibrary.wiley.com/doi/10.1111/j.1462-2920.2008.01567.x/abstract
Escherichia coli isolated from a Crohn's disease patient adheres, invades, and induces inflammatory responses in polarized intestinal epithelial cells.
Eaves-Pyles T, Allen CA, Taormina J, Swidsinski A, Tutt CB, Jezek GE, Islas-Islas M, Torres AG.
Texas, USA
http://www.sciencedirect.com/science/article/pii/S1438422107001233
2008
Crohn's disease-associated Escherichia coli LF82 aggravates colitis in injured mouse colon via signaling by flagellin.
Carvalho FA, Barnich N, Sauvanet P, Darcha C, Gelot A, Darfeuille-Michaud A
Clermont-Ferrand, France.
Crohn's disease-associated Escherichia coli LF82 aggravates colitis in injured mouse colon via signaling by flagellin
2009
Enterovirulent E. coli in inflammatory and noninflammatory bowel diseases.
Curová K, Kmetová M, Sabol M, Gombosová L, Lazúrová I, Siegfried L.
Kosice, Slovakia
http://link.springer.com/article/10.1007/s12223-009-0012-y
Molecular diversity of Escherichia coli in the human gut: new ecological evidence supporting the role of adherent-invasive E. coli (AIEC) in Crohn's disease.
Martinez-Medina M, Aldeguer X, Lopez-Siles M, González-Huix F, López-Oliu C, Dahbi G, Blanco JE, Blanco J, Garcia-Gil LJ, Darfeuille-Michaud A.
Girona, Spain
http://www.ncbi.nlm.nih.gov/pubmed/19235912
Adherent-invasive Escherichia coli, strain LF82 disrupts apical junctional complexes in polarized epithelia.
Eytan Wine, Juan C Ossa, Scott D Gray-Owen, and Philip M Sherman
Toronto, Canada
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2741472/pdf/1471-2180-9-180.pdf
Biofilm formation as a novel phenotypic feature of adherent-invasive Escherichia coli (AIEC).
Martinez-Medina M, Naves P, Blanco J, Aldeguer X, Blanco JE, Blanco M, Ponte C, Soriano F, Darfeuille-Michaud A, Garcia-Gil LJ
Girona, Spain
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2759958/
Crohn's disease adherent-invasive Escherichia coli colonize and induce strong gut inflammation in transgenic mice expressing human CEACAM.
Carvalho FA, Barnich N, Sivignon A, Darcha C, Chan CH, Stanners CP, Darfeuille-Michaud A.
Clermont-Ferrand, France
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757893/
Phylogenetic analysis of inflammatory bowel disease associated Escherichia coli and the fimH virulence determinant.
Sepehri S, Kotlowski R, Bernstein CN, Krause DO.
Manitoba, Canada
http://www.ncbi.nlm.nih.gov/pubmed/19462430
Similarity and divergence among adherent-invasive Escherichia coli and extraintestinal pathogenic E. coli strains.
Martinez-Medina M, Mora A, Blanco M, López C, Alonso MP, Bonacorsi S, Nicolas-Chanoine MH, Darfeuille-Michaud A, Garcia-Gil J, Blanco J.
Girona, Spain
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2786640/
Crohn's disease-associated adherent-invasive E. coli are selectively favoured by impaired autophagy to replicate intracellularly.
Lapaquette P, Glasser AL, Huett A, Xavier RJ, Darfeuille-Michaud A
Clermont-Ferrand, France
http://onlinelibrary.wiley.com/doi/10.1111/j.1462-5822.2009.01381.x/abstract
Adherent-invasive Escherichia coli target the epithelial barrier
Wine E, Ossa JC, Gray-Owen SD, Sherman PM.
Alberta, Canada
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023584/
2010
Role of decreased levels of Fis histone-like protein in Crohn's disease-associated adherent invasive Escherichia coli LF82 bacteria interacting with intestinal epithelial cells.
Miquel S, Claret L, Bonnet R, Dorboz I, Barnich N, Darfeuille-Michaud A.
Clermont-Ferrand, France
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2838056/
Abnormal CEACAM6 expression in Crohn disease patients favors gut colonization and inflammation by adherent-invasive E. coli.
Barnich N, Darfeuille-Michaud A.
Clermont-Ferrand, France
[URL="http://www.landesbioscience.com/journals/virulence/article/11510/?nocache=895750331"]http://www.landesbioscience.com/journals/virulence/article/11510/?nocache=895750331[/URL]
Complete genome sequence of Crohn's disease-associated adherent-invasive E. coli strain LF82.
Miquel S, Peyretaillade E, Claret L, de Vallée A, Dossat C, Vacherie B, Zineb el H, Segurens B, Barbe V, Sauvanet P, Neut C, Colombel JF, Medigue C, Mojica FJ, Peyret P, Bonnet R, Darfeuille-Michaud A.
Clermont-Ferrand, France
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2941450/
Abnormally expressed ER stress response chaperone Gp96 in CD favours adherent-invasive Escherichia coli invasion.
Rolhion N, Barnich N, Bringer MA, Glasser AL, Ranc J, Hébuterne X, Hofman P, Darfeuille-Michaud A.
Clermont-Ferrand, France
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2976078/
Genome sequence of adherent-invasive Escherichia coli and comparative genomic analysis with other E. coli pathotypes.
Nash JH, Villegas A, Kropinski AM, Aguilar-Valenzuela R, Konczy P, Mascarenhas M, Ziebell K, Torres AG, Karmali MA, Coombes BK.
Ontario, Canada
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091784/
Role of meprins to protect ileal mucosa of Crohn's disease patients from colonization by adherent-invasive E. coli.
Vazeille E, Bringer MA, Gardarin A, Chambon C, Becker-Pauly C, Pender SL, Jakob C, Müller S, Lottaz D, Darfeuille-Michaud A.
Clermont-Ferrand, France
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116889/
Translocation of Crohn's disease Escherichia coli across M-cells: contrasting effects of soluble plant fibres and emulsifiers.
Roberts CL, Keita AV, Duncan SH, O'Kennedy N, Söderholm JD, Rhodes JM, Campbell BJ
Liverpool, UK.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2976079/
2011
Crohn disease--associated adherent-invasive E. coli bacteria target mouse and human Peyer's patches via long polar fimbriae.
Chassaing B, Rolhion N, de Vallée A, Salim SY, Prorok-Hamon M, Neut C, Campbell BJ, Söderholm JD, Hugot JP, Colombel JF, Darfeuille-Michaud A.
Clermont-Ferrand, France
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049390/
A role for the RNA chaperone Hfq in controlling adherent-invasive Escherichia coli colonization and virulence.
Karina T. Simonsen, Gorm Nielsen, Janni Vester Bjerrum, Thomas Kruse, Birgitte H. Kallipolitis, Jakob Møller-Jensen
Odense, Denmark
http://www.plosone.org/article/info:doi/10.1371/journal.pone.0016387
The endoplasmic reticulum stress response chaperone: Gp96, a host receptor for Crohn disease-associated adherent-invasive Escherichia coli.
Rolhion N, Hofman P, Darfeuille-Michaud A.
Auvergne, France
http://www.landesbioscience.com/journals/gutmicrobes/article/15725/?nocache=1131403153
Analysis of Escherichia coli isolated from patients affected by Crohn's disease.
Raso T, Crivellaro S, Chirillo MG, Pais P, Gaia E, Savoia D.
Turin, Italy
http://link.springer.com/article/10.1007/s00284-011-9947-8
Adherent-invasive Escherichia coli phenotype displayed by intestinal pathogenic E. coli strains from cats, dogs, and swine.
Martinez-Medina M, Garcia-Gil J, Barnich N, Wieler LH, Ewers C.
Girona, Spain
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3165260/
Crohn disease-associated Escherichia coli promote gastrointestinal inflammatory disorders by activation of HIF-dependent responses.
Mimouna S, Gonçalvès D, Barnich N, Darfeuille-Michaud A, Hofman P, Vouret-Craviari V.
Nice, France
http://www.landesbioscience.com/journals/gutmicrobes/article/18771/?nocache=1310052539
Ex vivo intestinal adhesion of Escherichia coli LF82 in Crohn's disease.
Jensen SR, Fink LN, Nielsen OH, Brynskov J, Brix S.
Lyngby, Denmark
http://www.sciencedirect.com/science/article/pii/S0882401011001604
Adherent-invasive Escherichia coli induce claudin-2 expression and barrier defect in CEABAC10 mice and Crohn's disease patients.
Denizot J, Sivignon A, Barreau F, Darcha C, Chan HF, Stanners CP, Hofman P, Darfeuille-Michaud A, Barnich N.
Clermont-Ferrand, France
http://www.ncbi.nlm.nih.gov/pubmed/21688348
Role of meprins to protect ileal mucosa of Crohn's disease patients from colonization by adherent-invasive E. coli.
Vazeille E, Bringer MA, Gardarin A, Chambon C, Becker-Pauly C, Pender SL, Jakob C, Müller S, Lottaz D, Darfeuille-Michaud A.
Clermont-Ferrand, France
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116889/pdf/pone.0021199.pdf
Characterization of adherent-invasive Escherichia coli isolated from pediatric patients with inflammatory bowel disease.
Negroni A, Costanzo M, Vitali R, Superti F, Bertuccini L, Tinari A, Minelli F, Di Nardo G, Nuti F, Pierdomenico M, Cucchiara S, Stronati L.
Rome, Italy
http://www.ncbi.nlm.nih.gov/pubmed/21994005
Replication of Crohn's disease-associated AIEC within macrophages is dependent on TNF-α secretion.
Bringer MA, Billard E, Glasser AL, Colombel JF, Darfeuille-Michaud A.
Clermont-Ferrand, France
http://www.nature.com/labinvest/journal/v92/n3/full/labinvest2011156a.html
Crohn disease-associated Escherichia coli promote gastrointestinal inflammatory disorders by activation of HIF-dependent responses.
Mimouna S, Gonçalvès D, Barnich N, Darfeuille-Michaud A, Hofman P, Vouret-Craviari V.
Nice, France
http://www.landesbioscience.com/journals/gutmicrobes/article/18771/?nocache=1026489613
2012
Defects in autophagy favour adherent-invasive Escherichia coli persistence within macrophages leading to increased pro-inflammatory response.
Lapaquette P, Bringer MA, Darfeuille-Michaud A.
Clermont-Ferrand, France
http://onlinelibrary.wiley.com/doi/...ionid=4F9FD0741445725A8A6859EC750D6ABB.d01t02
AIEC colonization and pathogenicity: influence of previous antibiotic treatment and preexisting inflammation.
Drouet M, Vignal C, Singer E, Djouina M, Dubreuil L, Cortot A, Desreumaux P, Neut C.
Lille, France
http://www.ncbi.nlm.nih.gov/pubmed/22344932
A potential role of Escherichia coli pathobionts in the pathogenesis of pediatric inflammatory bowel disease.
Schippa S, Iebba V, Totino V, Santangelo F, Lepanto M, Alessandri C, Nuti F, Viola F, Di Nardo G, Cucchiara S, Longhi C, Conte MP.
Rome, Italy
http://www.nrcresearchpress.com/doi/abs/10.1139/w2012-007?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed&
Multidrug resistance is common in Escherichia coli associated with ileal Crohn's disease
Dogan B, Scherl E, Bosworth B, Yantiss R, Altier C, McDonough PL, Jiang ZD, Dupont HL, Garneau P, Harel J, Rishniw M, Simpson KW.
New York, USA
http://www.ncbi.nlm.nih.gov/pubmed/22508665
Infection strategies of enteric pathogenic Escherichia coli.
Clements A, Young JC, Constantinou N, Frankel G.
London, UK
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3370951/pdf/gmic-3-71.pdf
Bile salts induce long polar fimbriae expression favouring Crohn's disease-associated adherent-invasive Escherichia coli interaction with Peyer's patches.
Chassaing B, Etienne-Mesmin L, Bonnet R, Darfeuille-Michaud A.
Clermont-Ferrand, France
http://onlinelibrary.wiley.com/doi/10.1111/j.1462-2920.2012.02824.x/abstract
Adherent-invasive Escherichia coli blocks interferon-γ-induced signal transducer and activator of transcription (STAT)-1 in human intestinal epithelial cells.
Ossa JC, Ho NK, Wine E, Leung N, Gray-Owen SD, Sherman PM.
Toronto, ON, Canada
http://onlinelibrary.wiley.com/doi/10.1111/cmi.12048/abstract
The σE pathway is involved in biofilm formation by Crohn's disease-associated adherent-invasive Escherichia coli.
Chassaing B, Darfeuille-Michaud A.
Clermont-Ferrand, France
http://jb.asm.org/content/195/1/76.long
Crohn's disease-associated adherent-invasive Escherichia coli adhesion is enhanced by exposure to the ubiquitous dietary polysaccharide maltodextrin.
Nickerson KP, McDonald C.
Ohio, USA
http://www.plosone.org/article/info:doi/10.1371/journal.pone.0052132
Subversion of Autophagy in Adherent Invasive Escherichia coli-Infected Neutrophils Induces Inflammation and Cell Death
Abderrahman Chargui, Annabelle Cesaro, Sanda Mimouna, Mohamed Fareh, Patrick Brest, Philippe Naquet, Arlette Darfeuille-Michaud,Xavier Hébuterne, Baharia Mograbi, Valérie Vouret-Craviari, Paul Hofman
Nice, France
http://www.plosone.org/article/info:doi/10.1371/journal.pone.0051727
2013
Western diet induces dysbiosis with increased E coli in CEABAC10 mice, alters host barrier function favouring AIEC colonisation.
Martinez-Medina M, Denizot J, Dreux N, Robin F, Billard E, Bonnet R, Darfeuille-Michaud A, Barnich N.
Clermont-Ferrand, France
http://www.ncbi.nlm.nih.gov/pubmed/23598352
Crohn's disease AIEC invade macrophages by suppressing NFkB signaling
Khalidur Rahman, Maiko Sasaki, Jan-Michael A. Klapproth
Persistent infection with Crohn’s disease-associated adherent-invasive Escherichia coli leads to chronic inflammation and intestinal fibrosis
Cherrie-Lee N. Small, Sarah A. Reid-Yu, Joseph B. McPhee & Brian K. Coombes
Ontario, Canada
http://www.nature.com/ncomms/2013/130610/ncomms2957/full/ncomms2957.html
Serological markers predict inflammatory bowel disease years before the diagnosis.
van Schaik FD, Oldenburg B, Hart AR, Siersema PD, Lindgren S, Grip O, Teucher B, Kaaks R, Bergmann MM, Boeing H, Carbonnel F, Jantchou P, Boutron-Ruault MC, Tjønneland A, Olsen A, Crowe FL, Peeters PH, van Oijen MG, Bueno-de-Mesquita HB
Utrecht, The Netherlands
http://www.ncbi.nlm.nih.gov/pubmed/22842615
AIEC (LF82) are potently pro-inflammatory for monocytes, but not intestinal macrophages, in patients with crohn's disease.
Colonic mucosa-associated diffusely adherent afaC+ Escherichia coli expressing lpfA and pks are increased in inflammatory bowel disease and colon cancer
Maelle Prorok-Hamon, Melissa K Friswell, Abdullah Alswied, Carol L Roberts,Fei Song, Paul K Flanagan, Paul Knight, Caroline Codling, Julian R Marchesi, Craig Winstanley, Neil Hall, Jonathan M Rhodes, Barry J Campbell
Liverpool, UK
http://gut.bmj.com/content/early/2013/07/10/gutjnl-2013-304739.full.pdf+html
Increased S-Nitrosylation and Proteasomal Degradation of Caspase-3 during Infection Contribute to the Persistence of Adherent Invasive Escherichia coli (AIEC) in Immune Cells
Karl A. Dunne, Amr Allam, Anne McIntosh, Stephanie A. Houston, Vuk Cerovic,
Carl S. Goodyear, Andrew J. Roe, Scott A. Beatson, Simon W. Milling, Daniel Walker, Daniel M. Wall
Glasgow, UK
Queensland, Australia
http://www.plosone.org/article/info:doi/10.1371/journal.pone.0068386
Crohn's Disease-associated Adherent Invasive Escherichia coli Affect Levels of microRNAs in Intestinal Epithelial Cells to Reduce Autophagy
Hang Thi Thu Nguyen, Guillaume Dalmasso, Stefan Müller, Jessica Carrière, Frank Seibold, Arlette Darfeuille-Michaud
Clermont-Ferrand, France
http://www.gastrojournal.org/article/S0016-5085(13)01495-9/abstract
Last edited:
