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Crohn's Disease Forum » Treatment » Imuran/Azathioprine/6-MP » How high can the dose go before they have to try something else?


04-11-2011, 04:45 PM   #1
TheMrs
 
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How high can the dose go before they have to try something else?

I am currently on 200mg and while it HAS seemed to cut down the amount of flares I've had( mine are almost all extra intestinal, except for D and bleeding) a recent whopper of a flare affected my lungs and the pulmonologist said he's going to talk to my rheum about upping the imuran.

My husband is on it for a different condition and he takes 150, so I'm wondering if there is even much room to go up or if I'm going to have to switch meds.

Fwiw I'm fat from all the prednisone so I do outweigh him and I Believe it's based on weight but expect you have to max out at some point?
04-11-2011, 05:56 PM   #2
MapleLeafGirl
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My doc told me the max is 2.5 mg per kilogram (not sure what that converts to for pounds)
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Kelly

Diagnosed: August 2006
Current Meds: Imuran (125 mg), Budesonide (9 mg)
04-11-2011, 06:00 PM   #3
TheMrs
 
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Thanks! That's exactly what I needed to know.
04-26-2011, 05:25 PM   #4
LtHuff
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I am 155lbs and am at 350mg. I really am not sure how well its working as I still get flares, about every two weeks. I know if this doesn't work then the Doc is eyeing Remicade.
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Medications: 22APR11 Azathioprine (50mg) -
Remicade Fall 2014 every 8 weeks
04-27-2011, 02:18 PM   #5
Rebecca85
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If the max dose isn't working, there is also the option to lower the dose and take it with another medication (can't remember offhand, but it's used for gout and is warned against in the information leaflet) that affects the way the imuran is processed. Someone on here had to do that, but I can't remember who!
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Crohn's in the terminal ileum, dxed Jun '10

125mg azathioprine
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04-27-2011, 04:00 PM   #6
littlemissh
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Rebecca it's allopurinol.
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Diagnosed Crohns small bowel 2010,Gastroduodenal crohn's Jan 2012. Gastroparesis june 2014.
Duodenal perforation/peritonitis nov 2011. Portacath placed Nov 2013. Gastric pacemaker 2015.
Perforated jejenum/peritonitis oct 2015, PEJ for enteral feeding nov 2015

On Humira every 7 days, intermittent iv iron, regular blood transfusions :faint:
On TPN since March 2016.
04-30-2011, 09:21 PM   #7
spingirl
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I am about 140 lbs and take 150 mg. It sure does make my body achy.
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Crohn's Disease Forum » Treatment » Imuran/Azathioprine/6-MP » How high can the dose go before they have to try something else?
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