Share Facebook
Crohn's Disease Forum » Treatment » Humira/Adalimumab » Weight gain with Humira


05-19-2011, 02:06 PM   #1
tanya34
New Member
 
Join Date: May 2011
Weight gain with Humira

Has anyone gained a considerable amount of weight on Humira? I gained 70 pounds in my first year on Humira, and I understand that foods used to go straight through me and I was malnourished etc, but this abrupt gain is upsetting me. I eat good and I go to boot camp every day and I can not loose this weight. My GI told me that Humira does not cause weight gain. He also says it does not contribute to me catching colds and flus all the time too.
05-22-2011, 07:35 AM   #2
beth
Senior Member
 
Join Date: Mar 2009
Location: United Kingdom

My Support Groups:
Well Humira itself probably wont, but the reducing the inflammation that causes food to go straight through will! I've put on weight. The only thing is to eat less and/or boost your metabolism to burn the calories you do eat.
05-23-2011, 07:57 PM   #3
juicy24
Member
 
juicy24's Avatar
 
Join Date: Mar 2011
Location: Washington
After I had surgery and went on humira, I did the same thing I gained 50 lbs or so which I have never been over weight even eating the way I do. It was really fast too, which is weird. They say its cause I am not flaring but I don't know I never gained weight like this before.
__________________
Diagonsed at 19 had surgery in
Aug 2009 bowel resection and fistula fixed,
now it's IBS for me
currently on: Humira every 2 weeks,
Pentasa 2x day 500mg, Iron, B-12 shot,
hyoscyamine as needed
New med: belladonna-phenobarbital

have been on: Prednisone (which I will never take again), asacol (waste of time for me),
Entocort, sulfasalazine (made me have weird side affects),Remicade (Horriable reaction after 3rd dose)
05-24-2011, 08:42 AM   #4
tanya34
New Member
 
Join Date: May 2011
My fitness trainer has crohns and we share the same GI and when she took my weight gain to him and said she didnt want to try Humira because of the weight gain he told her she was too active to gain weight and that it wouldnt happen to her.... it will be interesting to see if she trusts him or not....
06-09-2011, 02:19 PM   #5
DougUte
Senior Member
 
DougUte's Avatar
 
Join Date: Jul 2010
Location: Kaysville, Utah

My Support Groups:
The weight gain could be due to not flaring. When I am flaring I lose weight like mad. When I am not flaring it all comes back. This has happened to me several times. I had Surgery in October 2010. By March I had gained about 40 lbs. (Luckily I had lost 40+lbs previous to the surgery, so I am just back to where I was. The only thing that changed was the diseased bowel being removed.
__________________
Surgery Oct 12, 2010

Crohns Medicines:
Started Humira June 22nd, 2011
Increased to weekly injections on November 1st, 2016
Due to the insurance company, Humira ended on January 31, 2017.
Started Entyvio February 9th, 2017
Loperamide 3 capsules twice a day
Vitamin B6, B12, Folic Acid
Vitamin D3 10000 I.U.
Nature Made Multivitamin
06-23-2011, 12:17 PM   #6
Lily Stiner
New Member
 
Join Date: Jun 2011
Juicy and Tanya, I feel your pain. My Crohn's went undiagnosed for quite some time, and I lost over 40 pounds during that period. Prednisone seemed to help, but I gained weight and was very puffy, sweat like a maniac in my sleep, and had to pee nonstop. I knew it was only a band-aid and not my maintenance medicine. I was put on Asacol, but since I have extreme difficulty swallowing pills (I even hired a hypnotist to help), I quit that medication and was unable to determine if it worked. Point is, it didn't work for me. Then my rhumatologist suggested Humira, and the results were astounding. My health had a complete turnaround. I finally could eat and live my life again, and without pills! The shots hurt like holy hell, but once every two weeks is doable.

I started Humira in April of 2010. Since then, I have gained 40 pounds. I'm not back to where I was by any means, because at my heaviest during my steroid use, I knew I was retaining water weight that didn't reflect my true number or size. Now, I'm bigger than ever. I work out 4 or more days a week and eat much healthier than ever, but I can't seem to drop it. Even during flares, when everything runs through me and I expect to see shrinkage, I stay the same. When I see pictures of myself, I think I look puffy or bloated again--I know that's not what I'm supposed to look like. All I can think of is the Humira, and I'm equally frustrated since all of the literature suggests it does not contribute to weight gain (if anything, they say to look out for weight loss). I'm nervous that this trend will continue to build my weight up even more over time as I continue with Humira. If you find any answers, I hope you will share.
06-23-2011, 09:19 PM   #7
Catie
 
Catie's Avatar
 
Join Date: May 2011
Location: Adelaide, South Australia, Australia

My Support Groups:
Sorry, I'm the opposite! I've lost nearly 20kg on Humira. I was quite overweight from prednisolone and the insatiable appetite that comes with it, but since starting Humira my appetite has become normal again. Helps that I'm now able to get out and exercise too!

I'd say most of the weight gain is from your bowel healing and being able to absorb things again...even though it seems like a huge amount in one hit. If you're flaring, your calorie absorption for the day might be 5-600, but if you're not, it would likely be around 12-1500. Also, your BMR is likely to be much higher when you're flaring as your body is in overdrive, whereas it would settle to a normal rate when you're not in a flare.
11-28-2013, 01:21 PM   #8
rachel3301
 
rachel3301's Avatar
 
Join Date: Sep 2012
Location: Wilmington, Delaware

My Support Groups:
I've been on Humira since Feb. 2013 and keep on gaining weight! I was 115 when I started and now weigh around 135! I haven't been this fat since my pregnancies and I don't enjoy it all. My GI doc says I'm just becoming a normal person again who should watch what they eat. Haha. I work out 3-4 times a week, but still not losing any blubber!
12-01-2013, 04:01 PM   #9
scoutfinch
Senior Member
 
Join Date: Apr 2011

My Support Groups:
Same here! I gained 20 lbs since starting Humira last year. But I was emaciated at the time so regaining the weight is a good thing. The first few months were THE BEST. I've been eating like a starved fiend. But I definitely need to start paying attention to my diet and start exercising to avoid getting out of shape.

Tanya, have you tried mixing up your exercise regimen? Or perhaps make some changes to your diet? Our metabolism changes as we age, so that may be a contributing factor too.
01-23-2014, 04:52 PM   #10
Lebobsigirl
 
Lebobsigirl's Avatar
 
Join Date: Jan 2014
I am glad (well not really) to see that others using Humira are struggling with weight gain. I have had Crohn's since 1988 and had a complete Colectomy in 2003. I fought flare after flare until I started Humira just a little over a year ago. I haven't felt better ...except I am up 2 sizes! I initially thought it was because things were being absorbed better in my body (YEAH) but at the price of gaining 25 pounds...UGH! If anyone finds a good and healthy way to take some weight off, please share! Signed, fat and not liking it!
03-13-2014, 12:27 AM   #11
Megslee03
 
Join Date: Mar 2014
Hello! I've been on humira for 6 months now and since staring treatment my weight has been the heaviest it's ever been, despite my clean eating and regular exercise. It's driving me crazy!!! So I have been talking to a Dr and she had a very interesting explanation for my weight gain...... Humira doesn't "stop" the body producing inflammation (tumour necrosis factor), it just blocks the receptors that the inflammation would normally "attach" to and start causing inflammation. The inflammation is still circulating through the body with no where to "attach" to. And when there is excess TNF floating around the body, the body's natural protective mechanism is to retain weight. I know this isn't a technical explanation but It's how I understand it. So now I'm seriously considering ceasing humira treatment.
Much love
Megan x
03-13-2014, 08:13 AM   #12
Lebobsigirl
 
Lebobsigirl's Avatar
 
Join Date: Jan 2014
Well that is frustrating for sure. I have to say that I do feel the best I have ever felt so I don't think stopping it would be a good idea. Especially knowing the extent of my disease. But really appreciate the explanation. They should probably add "weight gain" to their side affects listing. Take care Megan and thanks again!
03-14-2014, 06:18 AM   #13
n00b
Senior Member
 
Join Date: Oct 2011
Location: Suffolk, United Kingdom

My Support Groups:
Surely it is because the Humira is working and you are absorbing yuor food like a normal person??
03-14-2014, 08:47 AM   #14
Lebobsigirl
 
Lebobsigirl's Avatar
 
Join Date: Jan 2014
Completely agree!
03-14-2014, 07:44 PM   #15
Miss Underestimated
Senior Member
 
Miss Underestimated's Avatar
 
Join Date: Mar 2011
Location: Norfolk, Virginia
My weight gain is from cheescake, cookies, and Reese's peanut butter cups.
03-17-2014, 08:47 AM   #16
Lebobsigirl
 
Lebobsigirl's Avatar
 
Join Date: Jan 2014
That made me LOL!!!!!!
03-17-2014, 09:32 PM   #17
Miss Underestimated
Senior Member
 
Miss Underestimated's Avatar
 
Join Date: Mar 2011
Location: Norfolk, Virginia
Laughter is good medicine. I'm with you, not stopping my meds because I gained weight, although I was convinced it was from my blood pressure medication. Don't worry a lot about it - worry causes inflammation. Have a cookie.
03-18-2014, 07:06 AM   #18
scoutfinch
Senior Member
 
Join Date: Apr 2011

My Support Groups:
Laughter is good medicine. I'm with you, not stopping my meds because I gained weight, although I was convinced it was from my blood pressure medication. Don't worry a lot about it - worry causes inflammation. Have a cookie.
Laughter also burns calories! We should all laugh more.
03-18-2014, 08:06 AM   #19
Lebobsigirl
 
Lebobsigirl's Avatar
 
Join Date: Jan 2014
Cheers!
03-19-2014, 09:19 PM   #20
jt5
 
Join Date: Mar 2013
The weight gain could be due to not flaring. When I am flaring I lose weight like mad. When I am not flaring it all comes back. This has happened to me several times. I had Surgery in October 2010. By March I had gained about 40 lbs. (Luckily I had lost 40+lbs previous to the surgery, so I am just back to where I was. The only thing that changed was the diseased bowel being removed.
Just a random question, I am eating like crazy but not gaining weight and I'm having no symtoms of my crohns coming back, does it mean I'm flaring cause I feel like food is not absorbing at all. Just wondering if anyone knows! I really want to put on some weight
03-20-2014, 07:53 AM   #21
Lebobsigirl
 
Lebobsigirl's Avatar
 
Join Date: Jan 2014
Just wondering if you have had your thyroid checked? If you are not having diarrhea and you area eating a lot, that only stands to reason that it has to be something other than your Crohns. I'm no doctor, of course, but hey - it's worth an ask to the doc. Kinda wish that was my problem. HA I LOOK at food and it attaches to my butt! HAHA
09-26-2014, 10:23 AM   #22
Aprilshowers
 
Aprilshowers's Avatar
 
Join Date: Sep 2014
Location: Newmarket, Ontario
I have been using Humira for almost 2 years and six months ago the dose was increased to weekly. It has only been the last 10 days that I am suddenly gaining weight daily. It is very uncomfortable to say the least and none of my clothes fit. This is the heaviest I have ever been including while on Prednisone for several years. My diet/intake has not changed nor has my level of activity. Frustrating!
09-27-2014, 03:17 PM   #23
Jajabinks
Senior Member
 
Jajabinks's Avatar
 
Join Date: Jan 2014
Location: Westchester, New York

My Support Groups:
I hope I can gain some weight with Humira
__________________
Fish oil, turmeric powder, n-acetyl glucosamine, l-glutamine, slippery elm, marshmallow root, DGL, multivitamin, vitamin D. Crohns in terminal ileum. One semester left. Academics on hold thanks to painful Crohn's arthritis...
09-28-2014, 08:38 AM   #24
Patch
 
Patch's Avatar
 
Join Date: Jun 2014
Location: Michigan
I'm still 10-12 lbs less than I was a year ago, but at least Humira is helping me slowly gain it back. Maybe I'll even be able to top my old weight cap from when I was on Remicade. That might be nice.
11-07-2015, 05:02 PM   #25
wjm1973badgut
 
Join Date: Apr 2015
Location: aurora, Colorado

My Support Groups:
I think weight gain a real side effect. Although for me it was more minor and slow. With the healing we will gain weight and the doctors love that because they can see and quantify the change. My Eating habits were terrible when I first started recovery on Humira, due to the need to retain calories with Crohns. So that helped the weight gain. After the first 6 months I got my eating habits back to a normal amount of calories and still there is a tendancy to put on weight on the drug. It is very hard for me to lose weight now but I can with 3-4 workout/week and controlled calorie counts. Also weight and lbs are not evil to me, after you go through a Crohns ordeal extra weight can be a literal lifer saver, it helps put those extra lbs in focus.

Dx'd JAN ,3/2013
Meds: AZA, Lialdo .. almost no effect
LDN - 4 months - mild help,
Preg - 1 year on/off - good effect
humira 2.5 years - remission
12-05-2015, 12:26 AM   #26
Tanya K
 
Join Date: Feb 2014
Location: Illinois
Ugh! Glad to see an answer to my question on here. So frustrated with the weight gain-- thankful to be healthy....BUT these extra pounds need to go!
09-16-2017, 09:08 PM   #27
Hateibd73
 
Join Date: Sep 2017
Location: Mississauga, Ontario
Hi. I'm new to the forum. Just reasearching humira. I've seen half a dozen gi doctors over the course of twelve years all of which always told me to take biologics. I've always avoided them for fear of side effects but I think it's time I got my life back and will start next week on humira.
I'm actually looking forward to the weight gain. I'm not skinny by no means but hard to eat when you cannot digest anything.
Any help or advice you guys /girls have would be appreciated
Keith
09-18-2017, 02:24 PM   #28
DougUte
Senior Member
 
DougUte's Avatar
 
Join Date: Jul 2010
Location: Kaysville, Utah

My Support Groups:
After my surgery in 2010, I was put on Humira. As far as side effects.... what side effects. I had no side effects from Humira what so ever. It put me in remission and I got my life back. After about five years it started to slip up and I was slowly getting Crohns symptoms again. We tried to go to weekly injections, but my insurance company would not approve it, so I was switched to Entyvio. Humira was a very good medicine.

By the way, I have had no side effects from Entyvio either. The side effects of biologics sound awful, but I believe very few patients get the worst side effects. More likely to see injection site reactions from Humira than the other stuff. I hope the med works for you.
09-18-2017, 02:47 PM   #29
Hateibd73
 
Join Date: Sep 2017
Location: Mississauga, Ontario
Thanks for the reply. It eases my fear a little.
After my surgery in 2010, I was put on Humira. As far as side effects.... what side effects. I had no side effects from Humira what so ever. It put me in remission and I got my life back. After about five years it started to slip up and I was slowly getting Crohns symptoms again. We tried to go to weekly injections, but my insurance company would not approve it, so I was switched to Entyvio. Humira was a very good medicine.

By the way, I have had no side effects from Entyvio either. The side effects of biologics sound awful, but I believe very few patients get the worst side effects. More likely to see injection site reactions from Humira than the other stuff. I hope the med works for you.
10-12-2017, 09:42 AM   #30
RickS
 
Join Date: Jan 2016
Location: Ontario,Canada

My Support Groups:
I have gained weight as well, waist has gone up 2", had to buy new paints, probably 10-15 Lbs, all good to be relatively healthy again.
Reply

Crohn's Disease Forum » Treatment » Humira/Adalimumab » Weight gain with Humira
Thread Tools


All times are GMT -5. The time now is 08:13 PM.
Copyright 2006-2017 Crohnsforum.com