Glad you found the journal entries, I thought they'd somehow been deleted. It took a while for LDN to start to show improvements that I could really put faith in, and I was terrified I would fall into the small percentage it doesn't work for.... and if memory serves, I too got worse before things finally turned around. So, keep the faith... part of the issue may be that your immune system, your overall state of health, may be too weak for it to fight off the disease in any noticeable fashion at this point in time. Thing of it is, anti-biotics kill off both good and bad biotics within the system, so they may be slowing the ability for your immune system to put up a good fight. The success rate for treating Crohns with anti-biotics is pretty slim (one specialist I saw said it was less than 1:4, but 'they' had to try it on me just in case I was that lucky 1). It didn't work. Other point is that LDN can be delayed if you've got a case of candida blooming inside you at the same time (and don't even bother asking docs to treat candida, its like asking them to cure the common cold). If you have candida, or suspect you have, start taking daily doses of acidophilous (sp?). You can even have your LDN capsules compounded using it as a filler/binder Vs lactose. It shouldn't hurt, and it just might help. Be sure that the LDN you are using is fresh (the 50 mg pills have a shelf life of a year or more, but if they are using bulk Naltrexone powder, the active lifespan of any custom compounded pills is more like 90 -100 days, or at least that has been my personal experience. And be sure it is regular Naltrexone, and not the slow release version. For whatever reason, the SR type of Naltrexone just doesn't get it done. Last thing, rest, exercise, proper diet and sensible habits are part of my regimen. Not saying it is mandatory, just that it worked for me. Vitamins, supplements, pro-biotics, they are all good. Hope some of this helps.