So, I was diagnosed with Crohn's disease about 3 years ago and was being treated for the symptoms for a year before that. After having a perianal absess drained two years ago, I began remicade treatment in march of 2006. I was on 10mg/kg every month because that was the only way to keep my stomach pains from returning. In September, my doctor and I decided that the remicade was not being particularly effective given how high my dose was and the frequency of the infusions so I switched to Humira.
For the first injections, day 0 and day 14, I had no problems at all. However, shortly after, maybe a week later I started to develop headaches that have since then gotten progressively worse. I have since taken my day 28 and day 42 doses with my day 56 dose coming up Friday. The problem for me is that my headaches are getting so severe tylenol cannot cut it and even a vicodin barely manages to dull the pain. I am obviously going to talk to my doctor about this because it concerns me and I like being active in my treatments.
With that said I have a couple questions that I was hoping anyone with some experience might be able to help me with. My first question is, has anyone else experienced this and how did you deal with it? My second question is, would being off the remicade for 3 months be long enough to build up antibodies to it, given that my body was already becoming resistant to it? And finally, does anyone have any other suggestions that might help me because treatments like pentasa, flagyl, canasa, budesonide, and 6mp have all failed for me. Finally as a slightly off-topic note, the incision from my absess drainage has yet to heal after 2 years and while I know this can be perfectly normal, I wanted to know if anyone had suggestions for how to manage it other than regular baths preparation-H for the hemroids?
For the first injections, day 0 and day 14, I had no problems at all. However, shortly after, maybe a week later I started to develop headaches that have since then gotten progressively worse. I have since taken my day 28 and day 42 doses with my day 56 dose coming up Friday. The problem for me is that my headaches are getting so severe tylenol cannot cut it and even a vicodin barely manages to dull the pain. I am obviously going to talk to my doctor about this because it concerns me and I like being active in my treatments.
With that said I have a couple questions that I was hoping anyone with some experience might be able to help me with. My first question is, has anyone else experienced this and how did you deal with it? My second question is, would being off the remicade for 3 months be long enough to build up antibodies to it, given that my body was already becoming resistant to it? And finally, does anyone have any other suggestions that might help me because treatments like pentasa, flagyl, canasa, budesonide, and 6mp have all failed for me. Finally as a slightly off-topic note, the incision from my absess drainage has yet to heal after 2 years and while I know this can be perfectly normal, I wanted to know if anyone had suggestions for how to manage it other than regular baths preparation-H for the hemroids?