Share Facebook
Crohn's Disease Forum » Treatment » Methotrexate » Nervous about starting methotrexate! HELP?


10-18-2011, 07:59 AM   #1
SickChick
New Member
 
Join Date: Oct 2011
Location: Portsmouth, United Kingdom
nervous about starting methotrexate! HELP?

Hi guys.
i'm due to start Methotrexate in about a week and am really nervous after reading the scary side effects, so some info or advice from anyone who's on or been on it would be great!? Look forward to hearing from you.
Hannah xxx
10-18-2011, 09:17 AM   #2
Sjblanch1984
New Member
 
Join Date: Feb 2011
Location: harrisburg, Pennsylvania
yeah i pretty much refused to let my doctor put me on that crap
10-18-2011, 10:05 AM   #3
Norm47
New Member
 
Join Date: Oct 2011
Location: Ypsilanti, Michigan
Since starting on Methotrixate, my life long Crohns disease has been put in remission.
Plus it is so simple to take with a little sub -cu needle that you can't even feel!
The med dose not burn or give any other daily side effects. It has been the first medication that works beyond prednisone for me!

Look, all the IBD medications have side effects. Methotrixate has shown to have less then Remicade and others in that category

Go for it!
10-18-2011, 10:06 AM   #4
KayleighMeek
Forum Monitor
 
KayleighMeek's Avatar
 
Join Date: Dec 2010
Location: Southampton, United Kingdom

My Support Groups:
Hi Hannah,

I am currently on methotrexate and I felt the same as you really didn't want to go on it. The only side effects I have had is heartburn and nausea but docs have increased my folic acid to help that and it's not as bad now. Have you been on any other medications? If you haven't you could always ask to go on something else like 6pm or aza.
The methotrexate doesn't seem to be making much difference to my symptoms but I think I need a higher dose but docs won't until the heartburn is under control.
Hope whatever choice you make it helps x
10-18-2011, 08:17 PM   #5
slice
Member
 
slice's Avatar
 
Join Date: Sep 2009
Location: Philadelphia, Pennsylvania
I was more afraid of MTX than Cimzia by a longshot. Something about just seemed so horrible. Finally, it became clear that I needed to try something that might buy me some more time with the Cimzia, which was awesome for me, but gradually losing effectiveness. It's been so much better than I thought it would be. I take it at night so that the first several hours I sleep through. I have also had some increased heartburn but not all the time and some weeks nothing at all. My GI is not convinced it's related. There's no real harm in trying. YOu might not have any side affects and if you have some you don't like you can always go off of it. Good luck!
__________________
Dx'd Crohn's Colitis 2008
Dx'd Ankylosing Spondylitis 2011
Cimzia (400mg every 2 weeks)
15 mg Methotrexate
Rowasa (as needed)
10-19-2011, 01:44 AM   #6
Aura
Senior Member
 
Aura's Avatar
 
Join Date: Jun 2010
Location: Wellington, New Zealand
Hi ya, Mthx has put my crohns in remission for a year now, yea I get tired and a bit of nausea - but I can cope and manage this much better than a crohns flare. My bloods are monitored monthly and that is good to make sure everything is ok. I also get iron and b12 etc looked at too every now and then. I like to reward myself after my injection with a glass of fruit juice or something sweet, I find this makes me feel a bit better. It also helps me if I start to procrastenate with it. Good luck and keep us posted on your journey
__________________
Aura
DX 1998
Meds: 2.5mg Plendil ER. Azathioprine 100mg; Inhibace+ 12.5mg; gastrosoothe 60mg; Simvastatin 40mg; Loratadine 20mg; Fluoxetine 40mg; Provera 10mg; Metformin 2.55g; Cal d forte; 1.25mg, Humira; Panadol 4g; Pred 3mg
10-19-2011, 09:00 PM   #7
AZMOM
Moderator
 
AZMOM's Avatar
 
Join Date: Nov 2010

My Support Groups:
My daughter just started Methotrexate this summer. She took pills from June until September and then we converted to injections about a month ago. Honestly, we have not seen any of the scary side effects. She's been very healthy - no opportunistic infections, no hair loss, no nausea, liver is fine, none of that stuff. Now all that said, we're not sure it's going to keep her in remission but what I'm saying is that it is worth a shot!

J.
__________________
Julie

Mom to Claire - 11 going on 17

Dx JRA age 3, Crohn's age 6
Acute transverse myelitis at age 5

Started IVIG September 2016
Started Tacrolimus October 2016
Neurontin 100mg twice daily
Folic Acid
Calcium/D supplement
Daily Vitamin
Daily Probiotic

No more Enbrel, Stelara, Methotrexate, Allopurinal or 6MP
10-20-2011, 08:05 AM   #8
lseibert
Senior Member
 
lseibert's Avatar
 
Join Date: Aug 2010
Location: Shelby Township, Michigan

My Support Groups:
Good luck, hope all goes well!

I start Methotrexate pills on Saturday. I talked with my pharmacist about it and she said it's not as bad as the Remicade I was on last year.........

She said that Metho stops the progress of Crohn's, so I'm happy for that.

__________________
Linda

Crohn's Disease and IBS
Diagnosed: 2001 (symptoms for 22 years prior)
Currently on:
Desipramine for IBS, Vicoden for pain
Surgery: Small bowel strictureplasty 02/19/11 and 11/17/11, then a small bowel resection 4/6/12.
Yeah, 3 surgergies in 13 months
Supplements:
Multivitamins & Vitamin D3
Prednisone: Never again
Imuran (azathioprine)= Pancreatitis
Entocort EC (Budesonide) and medical adhesives = Rash
11-10-2011, 05:06 AM   #9
jaggartini
Member
 
Join Date: May 2011
Location: AUSTRALIA
Next stop for me will be Methotrexate I'd say. I was trying to avoid it but my gut feeling tells me I need it.
I hate the sound of it as it is a drug that just sounds so toxic. Your advised not to fall pregnant at all before or after taking it for some months which makes me often wonder what on earth would it be doing to my insides. (I'm done having babies by the way... phew)

I did react to Immuran so I cannot take that and it was not pleasant so I guess I'm in the situation "once bitten twice shy" scenario at the moment.
__________________
Ulcerative Colitis since 2004

Currently taking:
4 x 1g sachets Pentasa (every morning)
5mg x Prednisone
Probiotic Daily

Allergic Reaction to Imuran May 2011.
Reaction to Cyclosporin Nov 2011.
I've said no to Methotrexate as it sounds toxic and GI doesn't like using it.
Next stop may be surgery.

Had a major flare last Nov, hospitalised where I haemorrhaged. Ended up in ICU and blood transfusion.

.
11-10-2011, 05:39 AM   #10
JenniferH
 
JenniferH's Avatar
 
Join Date: May 2010
Location: Lymington, Hampshire, United Kingdom

My Support Groups:
I've been on methotrexate for about 6 months now and feel absolutely fine on it. Haven't had any real bad side effects as far as I know (always seem tired so not sure if that has to do with it?) but not sure how much it is helping my crohn's as still having symptoms sometimes. Having the monthly blood tests is very reassuring too as I feel I'm being monitored more regularly. Have tried azathioprine, infliximab, mecaptopurine and all had worse side effects.
__________________
Crohn's Diagnosis: 1988
Current meds: Humira, Loperamide, vitamin B12
Have previously been on infliximab (Remicade), Azathioprine (imuran), mercaptopurine and methatrexate, and lots and lots of steroids!

Surgeries: small bowel resection 1990, 2010
11-10-2011, 08:08 AM   #11
KWalker
Moderator
 
KWalker's Avatar
I used to take methotrexate pills but they would make me feel like complete crap, getting sick, hard to move, etc so the doctor switched me to injections (that I did myself) and I had no problems at all. I did it in the top of the leg, and I couldn't even feel it for the most part. I think the worst part was trying to get the stupid syringe full without any bubbles lol
11-10-2011, 08:34 AM   #12
lseibert
Senior Member
 
lseibert's Avatar
 
Join Date: Aug 2010
Location: Shelby Township, Michigan

My Support Groups:
I have been on the pills for 3 weeks, and I'm with you KWalker, I feel like crap. My Crohn's symptoms never stop, and I have new pain under all my ribs and on the left side.

I've also had scar tissue develop since my surgery in Feb. The Dr. went in with a colonoscopy and dilated it, but I'm still having pain from that 3 weeks ago.

I'm really hating everything right now, but I go to the Dr. today to see what he says. I'd rather take nothing than to feel like this.
Good luck everyone.....
11-10-2011, 12:25 PM   #13
Norm47
New Member
 
Join Date: Oct 2011
Location: Ypsilanti, Michigan
I used to take methotrexate pills but they would make me feel like complete crap, getting sick, hard to move, etc so the doctor switched me to injections (that I did myself) and I had no problems at all. I did it in the top of the leg, and I couldn't even feel it for the most part. I think the worst part was trying to get the stupid syringe full without any bubbles lol
Don't worry about the air bubbles....you should be using a small needle
(less than 1/2 inch) and just goes into tissue NOT a vein!
11-10-2011, 12:39 PM   #14
KWalker
Moderator
 
KWalker's Avatar
Oh really? Yeah the needles are really small. I was always told air bubbles are a big no no. I got good at it eventually lol but that's good to know. Thanks!
02-04-2012, 02:21 PM   #15
toneloc
 
Join Date: Dec 2010
Location: Girvan Ayrshire, United Kingdom
Hi everyone
I started Mrtho on Thursday 15mg (6 tabs) I also take 5mg folic acid and tons of toter tabs.
Should I be taking iron & b12 too?
My Crohn's has been flaring/bleeding for 8 months, I failed on 6-mp so they GI changed me to Metho.
Any advice greatly appreciated
Thanks
Reply

Crohn's Disease Forum » Treatment » Methotrexate » Nervous about starting methotrexate! HELP?
Thread Tools


All times are GMT -5. The time now is 10:20 PM.
Copyright 2006-2017 Crohnsforum.com