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Crohn's Disease Forum » Treatment » Imuran/Azathioprine/6-MP » Azathioprine For The Long Term?


02-07-2012, 01:03 PM   #1
NikiB
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Location: Burnaby British Columbia
Azathioprine For The Long Term?

Hello all!
I was just wondering how long people have been on Azathioprine and if it's made a difference in their disease. I have been on it for 9 months and so far so good. I guess Im looking for some success stories. So often I read about people having to jump around with medications. I know its often inevitable but I really hope to stay on Azathioprine for a while and maintain how good I feel right now. I appreciate any input
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Diagnosed January 2011-Crohn's disease
Abcess/fistula leading to
Bowel resection surgery April 2011
Have been on Entocort, Cipro, Flagyl
Currently on 175mg Azathioprine
40 mg Humira
02-07-2012, 01:21 PM   #2
DustyKat
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Location: New South Wales, Australia
Hey Niki,

Sarah has been on Imuran since her surgery 5 1/2 years ago and remains in remission. Matt has been on it since his surgery last April and is also in remission.

Good luck! I hope it continues to be successful for you!

Dusty. xxx
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Mum of 2 kids with Crohn's.
02-07-2012, 01:30 PM   #3
NikiB
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Location: Burnaby British Columbia
Thanx Dusty!
02-07-2012, 08:26 PM   #4
hawkeye
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Join Date: Mar 2011
Location: New Brunswick

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Been on it since 1991 - it has helped with the Salofalk for a maintenance med. Maybe wearing off now though as the flares seem to be more frequent. First flare was in 1996 then more frequent since 2009.
02-07-2012, 09:59 PM   #5
ekay03
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I have been on it since 2000. I have had one mild flare. I am quite happy with it.
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Crohns dx 1992
Bowel resection in 2000 and remission since then.
150mg Azathioprine maintenance dose
Nexium
Buspar
Zoloft
amlodipine
clonidine
Ferrous Sulfate
Folic acid
multivitamin
Bentyl as needed
Lyrica x2 daily for pain
Norco as needed for pain
Ondansetron as needed for nausea
Miacalcin for the bones
That's a lot of stuff, but I feel good

Friend me: http://www.facebook.com/profile.php?id=580468712
02-08-2012, 02:04 AM   #6
Rebecca85
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Location: Nottingham, UK
I have been on it for 17 months and no flares.
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Crohn's in the terminal ileum, dxed Jun '10

125mg azathioprine
4g Pentasa
02-10-2012, 05:41 AM   #7
ErikaHouston
 
Join Date: Oct 2010
Location: Charlotte, North Carolina

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13 months- in remission.
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3 Hemorhages (July '10, Sept '10, Oct '10) - no other Crohn's symptoms

Diagnosed Oct'10

Currently on Entocort and Apriso and starting Imuran in December '10

History of Melanoma ('08) so avoiding TNF blockers.
02-15-2012, 12:25 AM   #8
leithcote
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NikiB - again it's one of those things. Everyone's Crohn's/IBD/UC is unique to them, and some tolerate a particular drug or combination better than others. I've been on 6-MP for approx 7 months now (75mg daily), with fairly minimal side-effects. I just get very tired at times - oh, I got very sunburnt at one point! You should definitely remember to either stay out of the sun, or wear a high SPF suncream. I have a little network offs Crohnies here in Sussex and some of them have been on 6-MP very successfully for years. Hope it works out for you!
__________________

Tony

Crohn's - predominantly in the terminal ileum - diagnosed Oct 2010
Ileocolic resection - February 2012
Current Meds - Pentasa granules, 2 g sachet daily.
3 monthly B12 injection. Iron and Vitamin D supplements daily.
02-18-2012, 04:42 PM   #9
mohammed
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Join Date: Jun 2011
Location: Dammam, Saudi Arabia
the maximum dose is 2-2.5 mg / kg / day
but need regular monitor of blood count and liver function.
it take from 6 to 10 weeks to see the effect .
i am on it since 3 months and doing fine.
be aware that the severity of the disease is different from person to person .
__________________
Diagnosed 2001

surgical :
3 time fistula incision and drainge
2009 right hemicolectomy

medical :
predinslone many course
2008 humira
asacol
pentasa
remicade 2009
imuran 2011

current:
imuran 100 mg
remicade 5 mg per kg
pentasa
calciun and multivitamin
02-23-2012, 08:11 PM   #10
SapphireEyes
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Join Date: Feb 2012
I have been in remission and on only Aza for 14 years now for Crohn's colitis. I've had rectal fistulas, etc, you name it.

Well, I had squamous cell skin cancer and actinic keratosis treated recently and my GI doc has now thought it best to discontinue the Aza just this past Monday after these 14 years. Part of me was relieved to be off it because of the cancer, but now I'm worried about the unknown and am concerned about stopping it and causing a flare. Always called it the double-edged sword. I'm hoping my remission was not only from Aza but on my bodies own accord.
02-24-2012, 12:23 AM   #11
NikiB
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Location: Burnaby British Columbia
I have been in remission and on only Aza for 14 years now for Crohn's colitis. I've had rectal fistulas, etc, you name it.

Well, I had squamous cell skin cancer and actinic keratosis treated recently and my GI doc has now thought it best to discontinue the Aza just this past Monday after these 14 years. Part of me was relieved to be off it because of the cancer, but now I'm worried about the unknown and am concerned about stopping it and causing a flare. Always called it the double-edged sword. I'm hoping my remission was not only from Aza but on my bodies own accord.
The skin cancer risk concerns me too. I had a melanoma removed 4 years ago.
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