I was diagnosed with Crohn's just a few weeks ago. My doctor prescribed Lialda, Cipro, Prednisone and Imuran. I was off the Cipro within a week and the idea is that within two months I will be off all medication with the exception of Imuran. Last week I started to develop severe pains in my legs, in particular my right leg to the point that I could barely walk. I was told to stop the Imuran, did blood work and the usual suspects were fine (Potassium, Sodium, Magnesium). The pain came back and now the doctors have decided to wean me off Prednisone and see if that helps. I am back on Imuran. I realize that some of this is trial and error and each person's body is different but has anyone experienced similar pains? Not so much leg cramps but general pains toward the bottom of the leg, the right leg in particular. Also, any recommendations to reduce the pain? I have seen talk about heat pads, tonic water, Gatorade, etc. Any advice would be nice to have.