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Crohn's Disease Forum » Treatment » Humira/Adalimumab » Codeine and Humira


03-07-2012, 11:12 PM   #1
Barnacle
 
Join Date: Mar 2012
Codeine and Humira

I've been on Humira for awhile now and it's working well. However, I have some codeine that I need to take. Does anyone know if codeine and Humira have any sort of interactions? Anyone here ever taken both?
03-07-2012, 11:54 PM   #2
handle
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Join Date: Feb 2011
The two drugs operate via very different pathways and body systems, and I know of no interactions between them.

Codeine binds to receptors in the brain (opioid receptors) that are important for transmitting the sensation of pain throughout the body and brain.

Humira inhibits TNF-alpha production. TNF-alpha increases the phagocytic (white cells) killing activity.
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