Crohn's Disease Forum » Treatment » Methotrexate » Starting weekly methotrexate and FA

06-15-2012, 02:13 AM   #1
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Join Date: Aug 2010
Location: Perth
Starting weekly methotrexate and FA


Yesterday, my gastro finally decided to have me try methotrexate and perscribed 10mg along with a folic acid supplement that I'm supposed to take weekly (after being on mesalalazine since forever has done little to improve my health).

I was told to have a meal beforehand, drink plenty of water and not take the folic acid and methotrexate on the same day, but the thing is he didn't mention which to take first or how long after I should wait to take the other. So I was wondering if anybody here could help me get started?

06-15-2012, 09:54 AM   #2
Senior Member
Mom2oneboy's Avatar
Join Date: Mar 2012
Location: I'm a southern girl
My son just started Methotrexate and he took folic acid 5 days prior to having the injection. Hope this helps!
11yr old son
dx Crohn's 2/2012
Currently on VSL #3
Started EN 4/2
Methotrexate 6/6/12
Remicade 09/30/12

Life is not about waiting for the storms to pass...It's about learning to dance in the rain.
06-15-2012, 01:48 PM   #3
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KayleighMeek's Avatar
Join Date: Dec 2010
Location: Southampton, United Kingdom

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I always take my folic acid on Fridays and then have methotrexate on Monday's, easiest way to remember for me. But I have been told different things by different drs the GI dr told me to do it this way but my rheumatology told me something completely different. I am taken methotrexate tablets and not having the injections do I don't know if it varies with the two. Good luck with the new treatment
06-15-2012, 02:57 PM   #4
Senior Member
Join Date: Jun 2011
Location: Edmonton, Alberta

My Support Groups:
I just started as well and I take the Methotrexate on Fridays and then take the Folic Acid 48 hours after, so on Sunday.

I wanted to take it on a Friday in case it relly bothered me then I'd have the weekend to recover so i"d be good for work on Monday.
06-16-2012, 02:17 AM   #5
New Member
Join Date: Aug 2010
Location: Perth
Thank you so much for the replies Mom2oneboy and Kllyeve,
I ended up speaking to a friend of mine who's grandmother started on methotrexate for arthritis and said it didn't really matter.

KayleighMeek, that is really neat I think I'm going to try that and see how it goes
06-18-2012, 09:07 AM   #6
Join Date: Nov 2011
Location: Halifax, Nova Scotia
I am currently taking Methotrexate as well (25mg/1mL) by injection weekly and I supplement with Folic Acid, 1mg everyday. If I miss more than two days of FA, the nausea is horrible.
45 years old
UC diagnosed Dec/07
Crohn's diagnosed Nov/11
Methotrexate 25mg/weekly
Prevacid twice a day
Buscopan as needed
starting MLN002 soon
06-18-2012, 10:32 AM   #7
Senior Member
sfmreb2's Avatar
Join Date: Jan 2012
Location: walla walla, Washington
I took MTX weekly for about 5 years and took the Folic Acid daily. No problems that I know of.

Crohn's Disease Forum » Treatment » Methotrexate » Starting weekly methotrexate and FA
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