My husband was diagnosed with Pan UC in Oct 11'. He has never been in remission and we are now looking at surgery. He has had 2 hospital stays and was on prednisone for almost a year. He is finally weaned off but is no better. He goes probably 20 times a day, mostly bloodly and loose. He is constantly tired and all of his joints hurt. He is on Calcium 2000mg daily, Vitamin 2000iu daily, Imuran 100mg (anything more and he feels ill) and that is it. He was on Remicade they were giving him double doses every 4-6 weeks and it would help for maybe 2 weeks but that was it. They want him to start the predinsone again but we are both scared. While on it he balloon up, was moody and was always sweating. He recently had a bone density test and it came back on the low normal side. Whenever he eats he is in the bathroom within a few minutes, sometimes he doesn't even make it through the meal. The only other thing that was tried for him was Pentasa 8 tabs daily. That was only for a short period of time because of no improvement. I am at my whits end!!! I don't even know if he is getting the proper nutrition anymore. What else can we try????