Yeah, that sounds kinds weird to me too, Brian's Mom. C has never had extremely high results with blood work and inflammatory markers even during his worst points the labs didn't alarm anyone. So it was only when they got a look inside and saw the raging fire going on that the diagnosing GI said, "Hmmm...labs don't reflect severity for him."
At the time of C's first Fecal Calprotectin, we were about 6 months into treatment and he was having no where near the symptoms that he was before being dx'ed. But he had a couple of loose stools I asked for the FC, the GI nurse said well I'll ask the doc but his labwork just came back and it looks pretty good. The fecal calprotectin was 1700, you could've knocked me over with a feather, that high result was not what I was expecting at all looking at the lack of outward symptoms. It is when we added the MTX, his next FC test came back 300 so definitely a downward trend. We wouldn't have known to add the MTX had we relied on labwork or symptom levels alone.