Share Facebook
Crohn's Disease Forum » Parents of Kids with IBD » Efficacy of Methotrexate?


 
04-30-2014, 06:42 PM   #1
Clash
Forum Monitor
 
Clash's Avatar
 
Join Date: Apr 2012
Location: Georgia

My Support Groups:
Efficacy of Methotrexate?

So, I'm still in my bubble, but....

The last 3 days C has been having multiple bms, he says they aren't D but really soft. He insists he feels no CD symptoms, there is no mucus or blood with the bms and he has no joint pain. He believes that the reason his bms have been frequent and mushy is due to his new job and the fact that he has been grabbing food there on break. I'm not so sure but willing to wait it out and see a bit longer.

I know he is going to be apprehensive about alerting me to symptoms since I know he feels it could affect his new job. He knows his health comes first but he is also a teen that is ecstatic at the prospect of having his own money for the summer and the independence he feels that will bring.

Usually I have no problems discovering tell-tale signs since his episcleritis always gives him away, but allergy season is in full swing and his eyes are bearing the brunt of that so for now he has convinced me the redness is related to allergies.

The other biggie is no joint pain in the knees and here is where my question lies. He just switched to the MTX injections a little over a month ago for his spondylitis pain. So could MTX injections keep the joint pain that occurs concurrently with flares at bay as well?

He has been doing so well and I'm not ready to pop the bubble but I feel a little on edge since we are now 8 weeks out from last remi which is two weeks past his six week schedule.

So what are the committee's thoughts?

Oh and still gaining weight with EN.
__________________
Clash
Mom to
C age 19
dx March 2012 CD

CURRENT MEDS: MTX injections, Stelara


Dx May 2014: JSpA
8/2014 ileocecectomy
9/2017 G tube

PAST MEDS: remicade, oral mtx, humira
04-30-2014, 06:48 PM   #2
crohnsinct
Senior Member
 
Join Date: Mar 2012
Location: Connecticut

My Support Groups:
Not sure about if you are in a flare if mtx will keep the joint pain away thereby masking the flare BUT O was dx'd mtx for joint pain and it has taken it all away so it does help alleviate joint pain.

I could totally understand your heightened alert especially given all you guys are going through and the change in treatment etc. I would keep a watchful eye. Even in non IBDers bm's change and go through days of differences. He could be totally right about the different food he is eating. It is good he came to you and told you this much...here's hoping he doesn't hide anything more.
__________________
Daughter O dx 2/1/12 at age 12
Crohns & Remicade induced Psoriasis
Remicade
Methotrexate (12.5mg wkly - oral)
Vit d 2000IU
Multi vitamin plus iron
Calcium
Folic Acid
Previously used - Prednisone, Prevacid, Enteral Nutrition

Daughter T dx 1/2/15 at age 11
Vitaligo, Precoscious puberty & Crohns
Methotrexate (15mg weekly oral)
Enteral Nutrition
Entocort
IBD-AID Diet
Vit d 1000IU
Calcium
Folic Acid
Previously used: Mtx injections
04-30-2014, 06:50 PM   #3
my little penguin
Forum Monitor
 
Join Date: Apr 2012

My Support Groups:
No bubble popping just hugs

Search google scholar on Mtx efficacy joints and crohn's
__________________
DS - -Crohn's -Stelara
04-30-2014, 06:54 PM   #4
Maya142
Forum Monitor
 
Maya142's Avatar
 
Join Date: Jul 2013

My Support Groups:
MTX definitely helps M's joint pain -- knees, elbow, shoulders, fingers, hip and possibly lower back (though for AS studies seem to show that it does not help with spinal pain as you know).
Fwiw, M's GI was happy to keep her just on MTX for the Crohn's when she was diagnosed and said that should thought just the methotrexate would be effective for M (she was also on Enbrel for arthritis). That said, M's Crohn's is pretty mild so not sure it would work as well for more severe cases.
__________________
Mom of M (20)
diagnosed with Crohn's Disease at 16
Juvenile Idiopathic Arthritis at 12
Juvenile Ankylosing Spondylitis at 16

Mom of S (23)
dx with JIA at 14
Ankylosing Spondylitis at 18
04-30-2014, 06:54 PM   #5
Clash
Forum Monitor
 
Clash's Avatar
 
Join Date: Apr 2012
Location: Georgia

My Support Groups:
CIC, that is what I am hoping for. I'm not seeing any level of fatigue, I mean he is tired but it is a new job and he hasn't been incredibly active(physically) in quite awhile.

I did tell him today that I was willing to give it a few days and see if he is right about the food change but he needed to realize that hiding symptoms could be detrimental to his health long term and that if surgerywas the next step for him he'd rather be facing it on his terms instead of on a flare's terms.
04-30-2014, 07:01 PM   #6
Clash
Forum Monitor
 
Clash's Avatar
 
Join Date: Apr 2012
Location: Georgia

My Support Groups:
I'll check out that link my little penguin. But honestly, if you all feel that I am being naive speak up all advice and experience is welcome!

Maya142, C has still not complained of back pain so I think the MTX must be working on that pain as well. I'm not sure how helpful the injections will be with the CD as well, I got the feeling the GI wasn't exteremely hopeful that it would suffice.

This disease should come with an automatic medical degree, with specialties in endo, rheumy and gastro! Just like, "Here's your kid's dx and here are your degrees, congrats oh and no salary comes with your degrees!"
04-30-2014, 07:06 PM   #7
crohnsinct
Senior Member
 
Join Date: Mar 2012
Location: Connecticut

My Support Groups:
And all kids should have a check intestines light!
04-30-2014, 07:20 PM   #8
Clash
Forum Monitor
 
Clash's Avatar
 
Join Date: Apr 2012
Location: Georgia

My Support Groups:
Yes and a low vitamin/iron light!
04-30-2014, 07:59 PM   #9
my little penguin
Forum Monitor
 
Join Date: Apr 2012

My Support Groups:
When one of DS specialists suggest we needed to see xyz now- I told him I was planning on skipping that rotation. The doc just laughed .
04-30-2014, 08:51 PM   #10
Jmrogers4
Moderator
 
Jmrogers4's Avatar
 
Join Date: Jun 2012
Location: Boise, Idaho

My Support Groups:
Can we get like those stick on forehead thermometers but instead of temperature it has now worries, have a great day to call the GI now!
No bubble bursting here either, tell him he needs to stay healthy so he can spend all that money he's making this summer
__________________
Jacqui

Mom to Jack (18) dx Crohn's 2/2010
Vitamin D -2000mg
Remicade - started 1/9/14; 7.5ml/kg every 6 weeks
Centrum for Him teen multivitamin
Past meds: Imuran/Azathioprine; allopurinol; methotrexate; LDN; Prednisone; Apriso; Pentasa; EEN

Husband dx Crohn's 3/1993
currently none due to liver issues
04-30-2014, 09:57 PM   #11
Tesscorm
Moderator
 
Tesscorm's Avatar
 
Join Date: Jun 2011
Location: Ontario

My Support Groups:
Not exactly the same but may be somewhat related... S had lots of back pain bfr dx, GI wasn't sure if S taking advils for the pain triggered his crohns or if pain was associated inflation caused by crohns but, whatever came first, once he started on EEN the back pain went away! For the first year after dx, he had some back pain sporadically but even this has disappeared. Can't explain it and still unsure which came first but there was definitely a connection.

Just a thought on the job and earning spending money (if u do start feeling the job is too much). When my kids were younger, in high school, i gave them the option of either working or taking an extra credit in the summer (didn't want them sitting at home doing nothing!). If they took a summer class, I paid them based on their mark - if they ended with an 80, I gave them $80 per week, 70 was $70, etc. (anything less than 60 got nothing bcz I told them they obviously hadn't worked! ). But it allowed them to 'earn' some spending money (and get an extra credit) and I figured, if they hadn't found a job, I wudve ended up giving them spending money anyway!
__________________
Tess, mom to S, 22
Diagnosed May 2011

Treatment:
May-July 2011 - 6 wks Exclusive EN via NG tube - 2000 ml/night, 1 wk IV Flagyl
July 2011-July 2013 - Supplemental EN via NG, 1000 ml/night, 5 nites/wk, Nexium, 40 mg
Feb. 2013-present - Remicade, 5 mg/kg every 6 wks
Supplements: 1-2 Boost shakes, D3 - 2000 IUs, Krill Oil
04-30-2014, 10:07 PM   #12
Clash
Forum Monitor
 
Clash's Avatar
 
Join Date: Apr 2012
Location: Georgia

My Support Groups:
That's a great idea Tesscorm. C is taking an SAT prep course this summer. Not entirely sure why as his next test dateb is in June and the class doesn't start til mid June but he says he wants to be prepared in case he is flaring the second time as well(first SAT was week he was released from hospital.)

He can bring a meal for break so he is going to do that to see if it brings bms under control.

I didn't even think about EN maybe helping with that, thanks!

Oh and J his sister wanted the Grands to implement that plan for the whole of college! LOL!
05-01-2014, 08:15 AM   #13
DustyKat
Super Moderator
 
DustyKat's Avatar
 
Join Date: May 2010
Location: New South Wales, Australia
I agree with the Metho having the ability to treat more than one co-morbidity.

Is the food that C is having at work what he is use to eating, I don’t imagine it would be what he is use to everyday, and is it fatty type food?
I only ask as he has ileal disease with ?scarring. That being the case his bowel motions may have changed to that due to fat malabsorption. I don’t imagine EN on top of it would help in regard to stool consistency. Just a thought in view of no other overt symptoms.

Dusty. xxx
__________________
Mum of 2 kids with Crohn's.
05-01-2014, 08:22 AM   #14
Clash
Forum Monitor
 
Clash's Avatar
 
Join Date: Apr 2012
Location: Georgia

My Support Groups:
Dusty, that is what we are hoping that even though it isn't completely out of his norm it is more frequent and maybe that is what has caused the shift. Wow I hadn't even thought of the EN playing a role too! Thanks! Hell, my bubble feels fully in tact I may toast it with wine...hmm maybe a bit early...nah!
05-01-2014, 08:40 AM   #15
DustyKat
Super Moderator
 
DustyKat's Avatar
 
Join Date: May 2010
Location: New South Wales, Australia
Well you know the song…It’s 5 o’clock somewhere…better still it’s 11:40pm here so you are well overdue!
05-01-2014, 05:55 PM   #16
AZMOM
Moderator
 
AZMOM's Avatar
 
Join Date: Nov 2010

My Support Groups:
Dusty - Pour me one.

MTX is our route for now. It doesn't always work great for Claire BUT it did work well for quite some time. I think while it may not be the "first choice" - it can definitely work for some.

Dusty - I'm still waiting.

J.
__________________
Julie

Mom to Claire - 11 going on 17

Dx JRA age 3, Crohn's age 6
Acute transverse myelitis at age 5

Started IVIG September 2016
Started Tacrolimus October 2016
Neurontin 100mg twice daily
Folic Acid
Calcium/D supplement
Daily Vitamin
Daily Probiotic

No more Enbrel, Stelara, Methotrexate, Allopurinal or 6MP
05-01-2014, 06:00 PM   #17
DustyKat
Super Moderator
 
DustyKat's Avatar
 
Join Date: May 2010
Location: New South Wales, Australia
Yeah well don’t hold your breath. The goon sack is on the floor and dry as a bone with the cat laying on it.
05-01-2014, 06:15 PM   #18
Clash
Forum Monitor
 
Clash's Avatar
 
Join Date: Apr 2012
Location: Georgia

My Support Groups:
Ummm should I even ask what a goon sack is?
05-01-2014, 06:19 PM   #19
DustyKat
Super Moderator
 
DustyKat's Avatar
 
Join Date: May 2010
Location: New South Wales, Australia
Dirty minded girl!

You know, the bladder out of cask wine…



…so many games and fun uses to be had with them.

Mind you they are becoming very upmarket!…

05-01-2014, 06:27 PM   #20
Clash
Forum Monitor
 
Clash's Avatar
 
Join Date: Apr 2012
Location: Georgia

My Support Groups:
Ahhh okay, so here it would be like a case of wine though I'm not sure how upscale they have become here as I've only noticed them in the grocery store never had one.

But we recently tried these:

05-01-2014, 06:29 PM   #21
Clash
Forum Monitor
 
Clash's Avatar
 
Join Date: Apr 2012
Location: Georgia

My Support Groups:
Oh well can't figure out how to post it from my mobile but Cops De Vino is the name of the product.
05-01-2014, 06:57 PM   #22
DustyKat
Super Moderator
 
DustyKat's Avatar
 
Join Date: May 2010
Location: New South Wales, Australia
Would one glass be enough though??

Isn’t this a case of wine??



Streuth, how did we get to this from Metho??
05-01-2014, 07:07 PM   #23
Tesscorm
Moderator
 
Tesscorm's Avatar
 
Join Date: Jun 2011
Location: Ontario

My Support Groups:
Its a quick and slippery slope to that first drink! Just ask our mayor!!
05-01-2014, 07:07 PM   #24
AZMOM
Moderator
 
AZMOM's Avatar
 
Join Date: Nov 2010

My Support Groups:
Okay now I'm in hysterics
05-01-2014, 07:13 PM   #25
Clash
Forum Monitor
 
Clash's Avatar
 
Join Date: Apr 2012
Location: Georgia

My Support Groups:
Haha! Yeah I guess the word I was looking for was box wine! Honestly, though I'm not picky as long as it is great at bubble support!
05-01-2014, 07:23 PM   #26
crohnsinct
Senior Member
 
Join Date: Mar 2012
Location: Connecticut

My Support Groups:
Its a quick and slippery slope to that first drink! Just ask our mayor!!
LMAO! I saw video of his dancing skills...he can ride the Crohn's party bus with us...bet he would be a hoot with the pole!
05-01-2014, 07:35 PM   #27
DustyKat
Super Moderator
 
DustyKat's Avatar
 
Join Date: May 2010
Location: New South Wales, Australia
Your mayor even made the news at the arse end of the world!
05-01-2014, 07:40 PM   #28
Farmwife
Forum Monitor
 
Farmwife's Avatar
 
Join Date: Apr 2012
Location: Michigan

My Support Groups:
Its a quick and slippery slope to that first drink! Just ask our mayor!!
Yes, ALL Michigan sighed and was thankful it wasn't any of our mayors.
__________________
I'm mom to............... Little Farm Girl 8 yr old
Ibd (microscopic)
(12/28/12),
dx Juvenile Arthritis
(12/13/13)
dx Erthema Nodosum
(8/13/14)
Bladder and Bowel Dysfunction
(10/14/13)
Ehlers-Danlos Syndrome dx (1/26/17)
Remicade started on (9/8/14)Every 4 wks
Azathroprine started on 10/9/15
EN/EEN- since (1/12/13)
Past Meds- LDN, Humira, Pred, MTX, Sulfasalazine
05-01-2014, 07:42 PM   #29
Tesscorm
Moderator
 
Tesscorm's Avatar
 
Join Date: Jun 2011
Location: Ontario

My Support Groups:
OMG!!! CIC! THAT is a rotten visual!! Him and a pole!

But, Clash... he did find his bubble!!

pic1.jpg
05-01-2014, 07:46 PM   #30
Tesscorm
Moderator
 
Tesscorm's Avatar
 
Join Date: Jun 2011
Location: Ontario

My Support Groups:
Your mayor even made the news at the arse end of the world!
Toronto's finest!!

pic1.jpg pic2.jpg
pic3.jpg
Reply

Crohn's Disease Forum » Parents of Kids with IBD » Efficacy of Methotrexate?
Thread Tools


All times are GMT -5. The time now is 12:06 PM.
Copyright 2006-2017 Crohnsforum.com