08-03-2014, 09:55 AM   #1
my little penguin
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Bloodwork changes

DS went to ped yesterday - sore armpits ped found a small bump so ordered fast bloodwork we are in the clear for the bump side but
Albumin is a lot lower 3.7 was 4.2
Hct is low (36.1)
Alt is up was 21 for months now 31
Hcb is about the same 12.8
Ferritin is up 34 from 10 in January
Sed rate up to 19 from 10 at the end of may

Something is going on

Could low albumin and higher alt be from arthritis ?
DS - -Crohn's -Stelara -mtx
08-03-2014, 10:03 AM   #2
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Clash's Avatar
I definitely don't have an answer to that although it hasn't been the case with C's SpA dx. Maybe maya142 will be about soon. Hugs
Mom to
C age 19
dx March 2012 CD

CURRENT MEDS: MTX injections, Stelara

Dx May 2014: JSpA
8/2014 ileocecectomy
9/2017 G tube

PAST MEDS: remicade, oral mtx, humira
08-03-2014, 12:07 PM   #3
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Maya142's Avatar
No idea - M's blood work tends to be perfect, besides anemia and high ferritin.
Could the higher ALT be from MTX?
Sending hugs!
Mom of M (20)
diagnosed with Crohn's Disease at 16
Juvenile Idiopathic Arthritis at 12
Juvenile Ankylosing Spondylitis at 16

Mom of S (23)
dx with JIA at 14
Ankylosing Spondylitis at 18
08-03-2014, 12:09 PM   #4
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Location: Michigan

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"Low albumin levels can also be seen in inflammation, shock, and malnutrition. They may be seen with conditions in which the body does not properly absorb and digest protein, such as Crohn's disease or celiac disease, or in which large volumes of protein are lost from the intestines."

Lots of info here. It can also be from liver or kidney issues.
I'm mom to............... Little Farm Girl 9 yr old
Ibd (microscopic)
dx Juvenile Arthritis
dx Erthema Nodosum
Bladder and Bowel Dysfunction
Ehlers-Danlos Syndrome dx (1/26/17)
Remicade started on (9/8/14)Every 2 wks
MTX started AGAIN on 11/21/17
EN/EEN- since (1/12/13)
Past Meds- LDN, Humira, Pred, MTX, Sulfasalazine,
08-03-2014, 12:50 PM   #5
my little penguin
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He never had high alt before on Mtx but has on 6-mp which is why we had to stop it.
His sed rate is consistently at 10 unless his crohn's was flaring .
His albumin has also always been in the higher range .
Need to call the Rheumo/gi on Monday .

Hct has been lower before but that was at the beginning of his dx .

His crohn's seems to be fine but his arthritis no near controlled.
08-03-2014, 06:40 PM   #6
Jmrogers4's Avatar
No answers, just lots of hugs and hope it all gets sorted out quickly

Mom to Jack (18) dx Crohn's 2/2010
Vitamin D -2000mg
Remicade - started 1/9/14; 7.5ml/kg every 6 weeks
Centrum for Him teen multivitamin
Past meds: Imuran/Azathioprine; allopurinol; methotrexate; LDN; Prednisone; Apriso; Pentasa; EEN

Husband dx Crohn's 3/1993
currently none due to liver issues
08-05-2014, 03:27 PM   #7
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ALT and AST are for liver.( Meds can get it high) Usually range is 0 to 40 depending on lab. Albumin by it self is not that important what matters is A/G ratio. At least is what our Pedi says. Do you know the ref. range for sed? I know my lab is 0 to 15. So at 19 he is having some inflammation, maybe from arthritis? I hope is nothing serious.
Mom/ Girl 19
dx 2011 crohn's in terminal ileum, peri-anal
Prior Meds Asacol, Prednisone, nexium
Current meds.
Remicade since Nov. 2012
5000 Vit. D, Multi-Vitamins with Iron
Currently in REMISSION :dance

Mom/ 16 boy
Amplified musculoskeletal pain
Prior. Prednisone, sulfasadine,
Currently. Celebrex, gabapentin, amitriptyline.
08-05-2014, 03:47 PM   #8
my little penguin
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Thanks Araceli
DS has had alt/ast numbers triple the normal reference range while on 6-mp so we know meds can go to his liver quickly so any increase even when it's still within normal starts to cause concern since he was on biologics for tha past two years without any increase at all .
Add in he is not therapuetic on Mtx yet .

Talked with the Rheumo. His doc is not in.
08-10-2014, 05:17 PM   #9
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Patricia56's Avatar
Join Date: Jul 2012
Location: Northern California, USA
growth can cause elevated ALT.

Inc ferritin c/b sign of inflammation along with lowered albumin, drop in Hct, elevated ESR. Does your doc run CrP?

None of these are specific markers so it's impossible to know if it's from the arthritis, CD or a combo of the two.
Badger, 18, CD, overall great guy
Dxd age 10, 2006 after nearly 1 year of active sx
Current CD meds: Remicade, Methotrexate and Omeprazole, Vit. D, Calcium, Folic Acid, Probiotic

Nothing I say here should be construed as medical advice. I am not a doctor. These are just my opinions.
08-10-2014, 06:35 PM   #10
my little penguin
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Crp was normal which it always is.
His arthritis is getting worse ( barely tie his shoes or put on socks some days ).
So I assume its that since things are ok Gi wise .

Good to keep in mind about alt .
He sees both gi\rheumo in a few weeks .
08-10-2014, 10:08 PM   #11
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Maya142's Avatar
Fwiw, when M's ferritin is high (from inflammation) it is significantly above the upper the limit. Three months ago it was over 140 points above the upper limit. This month, it's only 40 points above the upper limit.
In her case, they think it's from the arthritis and not the IBD.

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