Link between Juvenile Spondylarthritis and inflammatory bowel by Gut bacteria

To the increasing hints that disturbances in the human-bacterial ecosystem may be at the root of rheumatic disease, add this: Children with spondyloarthritis (SpA) have the same low levels of a microbe called Faecalibacterium prausnitzii that occur in children with inflammatory bowel disease.

This brings a microbiome connection to two autoimmune disorders that also have "strong clinical and pathological links," observed Matthew Stoll MD, an assistant professor of rheumatology in the division of pediatric rheumatology at the University of Alabama-Birmingham. At the ACR pediatric rheumatology meeting in Orlando, Stoll described studies that used DNA sequening to characterize all species of enteric bacteria in 28 children with enthesitis-related arthritis and 13 controls who were either healthy or had non-inflammatory joint pain.

- See more at: http://www.diagnosticimaging.com/ac...ldhood-spondyloarthritis#sthash.pyieLzJF.dpuf

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