My daughter has been fighting this disease for a year now. We have been through two doctors at our Children's Hospital (original left to start a new hospital in Texas). Nothing actually has worked - her body was not able to process the 75 mg of Imuran. She was dropped down to 25 mg and it has staved off the disease elsewhere but not helping her where her Crohn's is present. Now a year later her calprotectin level is at 629 down from 820 in May and she is flaring and in her first week of college! She has been on 9mg of entocort since May. Now her GI here at Children's Hospital and the new GI (grown up doc at college as she calls him) both agree we need to start a biologic and agree that Humira would be easier for a college student. We are starting the process now (bloodwork, insurance approvals). I so just want her to get some relief -but I am so scared of the side effects of Humira in young adults (she's 18)!! Does anyone out there have teenage children on this and if so how are they doing? I don't see that we have much choice the meds are not working and they are saying that she is too young to operate on because her inflammation is at the terminal ileum (stricture) and involves the valve and they are afraid she will lose the valve. Both doctors agree that should be a last resort. Sorry to ramble - just a scared Mom trying to justify what we are about to do!