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Crohn's Disease Forum » Parents of Kids with IBD » 2nd quantiferon test


01-30-2015, 01:59 PM   #1
CDJ
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2nd quantiferon test

Josh's 2nd quantiferon blood test came back indeterminate again. Apparently this means that Josh has had contact with someone who has TB somewhere along the line. This is not the result we wanted as it delays the Infliximab yet again. The consultant is going to talk to a microbiology doctor to see what they say.
They are still saying he can have Infliximab but will needed to be treated with prophylactic treatment along side the Infliximab. But as yet don't know when this will start.

Has this happened to anyone else whose child started Infliximab? I just wondered how common this is?
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01-30-2015, 02:35 PM   #2
nogutsnoglory
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My test came back indeterminate as well. Ask for a PPD. they inject a lliquid bubble beneath the skin and check 2 days later to see the size. This can rule out TB.
01-30-2015, 02:46 PM   #3
CDJ
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What's a PPD test? Is this similar to the old BCG test we had when we were at school where they do a skin test before the actual vaccination?
I will ask about this test on Monday.
01-30-2015, 03:33 PM   #4
nogutsnoglory
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I'm not sure about that test but it looks like the one I'm talking about is called the Mantoux test in the UK: http://en.m.wikipedia.org/wiki/Mantoux_test
01-30-2015, 04:29 PM   #5
Worried mama
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My son had the PPD test done as well. Our pediatrician did it. They stick a tiny needle under skin on forearm and then you return 2 days later and they just look at it. PS, do you mind messaging me to let me know how your son got over his needle phobia? It takes at least 3 people to hold my son down for any type of needle, and there are many needles. I don't want to hijack your thread here....tx.
01-30-2015, 06:03 PM   #6
kimmidwife
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The PPD is more accurate then the Mantoux test. I would ask for that and also a chest X-ray which can usually help rule things out as well. I am on a Facebook page for kids with IBD and this has happened to several kids on that page. They were put on prophylactic treatment.
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01-30-2015, 06:55 PM   #7
my little penguin
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Same here ppd test every year Gi said too many false positives on the blood test .
Good luck
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01-31-2015, 12:34 AM   #8
DustyKat
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Mantoux and PPD are the same test. PPD is the type of tuberculin injected and Mantoux is the test technique used.

I am surprised they havenít used this test given the indeterminate result of the Quantiferon Gold.

Dusty. xxx
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01-31-2015, 07:37 AM   #9
malorymug
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Hi, Indeterminate does not mean TB!!!

So we had this problem too. The quantiferon test was indeterminate and a chest xray that found "dense nodules". We also are often exposed to folks that could easily have tb (dense, transient populations). I thought for certain my kid had tb.

We followed up with doing the old fashion skin test (PPD or Mantoux) and it should no antibodies tb. We also had a ct scan of his lungs to show that the dense nodules were not tb. Still working on what they are.

With those two negatives we felt confident to start the infliximub.

I would not give in to taking tb meds prophylaxis easily. In my humble opinion, they are so very strong drugs.

Indeterminate does not mean TB!!!
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02-01-2015, 03:47 AM   #10
CDJ
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Malorymug, I do realise that this doesn't mean that Josh has TB. It is interesting too that your son also had the same problem. This is the second test that has come back with the same results. I am not sure how often this happens? I know Josh's IBD nurse seems to think this quite rare.

I am hoping for Josh to start Infliximab soon as nothing else is working now. He is still on 40mg steroids as each time we try reducing down his symptoms return.

I will speak to the IBD team tomorrow to see what the next step is now.
02-01-2015, 06:18 PM   #11
kimmidwife
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Oops dusty I meant to say ppd is more accurate then quantiferon not Mantoux as you are right they are the same test!
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