Share Facebook
Crohn's Disease Forum » Books, Multimedia, Research & News » An update on the use and investigation of probiotics in health and disease


03-05-2015, 05:59 AM   #1
DustyKat
Super Moderator
 
DustyKat's Avatar
 
Join Date: May 2010
Location: New South Wales, Australia
An update on the use and investigation of probiotics in health and disease

Includes IBD…

Abstract:

Probiotics are derived from traditional fermented foods, from beneficial commensals or from the environment. They act through diverse mechanisms affecting the composition or function of the commensal microbiota and by altering host epithelial and immunological responses. Certain probiotic interventions have shown promise in selected clinical conditions where aberrant microbiota have been reported, such as atopic dermatitis, necrotising enterocolitis, pouchitis and possibly irritable bowel syndrome. However, no studies have been conducted that can causally link clinical improvements to probiotic-induced microbiota changes. Whether a disease-prone microbiota pattern can be remodelled to a more robust, resilient and disease-free state by probiotic administration remains a key unanswered question. Progress in this area will be facilitated by: optimising strain, dose and product formulations, including protective commensal species; matching these formulations with selectively responsive subpopulations; and identifying ways to manipulate diet to modify bacterial profiles and metabolism.
Full Article:

http://m.gut.bmj.com/content/62/5/78...d-3f5f220ebf99
__________________
Mum of 2 kids with Crohn's.
03-05-2015, 06:16 AM   #2
SJ!
 
Join Date: Dec 2012
Location: Sydney, New South Wales, Australia

My Support Groups:
You have to be careful of S boulardii whilst on infliximab as it can cause fungemia

I only found this out recently as Greg has C diff and we were looking at probiotics.
__________________
Sarah xx Swimming Teacher

Wife to Greg who has Indeternminate Colitis

Diagnosed November 2012 Indeternminate Colitis

Current Meds.
3.5grams Sulfasalazine
Remicade
Prednisone
Vancomycin
Vitamin D
Iron[/COLOR]
Previous:2012 PANCOLITIS, C-Diff, 100mg IV pred, Vancomyacin, Flagyl, blood transfusions.
Reply

Crohn's Disease Forum » Books, Multimedia, Research & News » An update on the use and investigation of probiotics in health and disease
Thread Tools


All times are GMT -5. The time now is 09:27 AM.
Copyright 2006-2017 Crohnsforum.com