Share Facebook
Crohn's Disease Forum » General IBD Discussion » Biopsies negative but ulcers in ileum?


04-01-2016, 04:27 PM   #1
Qwerty
 
Join Date: Apr 2016
Location: Idaho
Biopsies negative but ulcers in ileum?

I've been having blood in my stool and some mucus. Lots of abdominal pain and cramping. Years this has been the case. Colonoscopy a few days back showed ulcers in the ileum. Biopsies were apparently negative. Sooooo... I go back in a couple of weeks to talk about more testing. The nurse said it could still be Crohn's, that is what the additional testing is for. Is this situation common?

I was just so looking forward to finally having some answers and here I am just as lost as before. Has anyone else had negative biopsies and still had Crohn's?
04-01-2016, 05:17 PM   #2
ronroush7
Forum Monitor
 
ronroush7's Avatar
 
Join Date: Oct 2013
Location: vienna, Virginia

My Support Groups:
I think ulcers in the ileum could indicate IBD. Let us know
04-01-2016, 08:13 PM   #3
stylinmama
Senior Member
 
Join Date: Jun 2010
Location: Saskatchewan

My Support Groups:
What were they looking for in the biopsy? You can't really get a "negative" result for Crohn's as there is no one test that definitively says "it's crohns". It's usually *diagnosed* with multiple tests and symptoms.
04-02-2016, 02:27 AM   #4
Plittler
 
Plittler's Avatar
 
Join Date: Jan 2016
Location: Bristol, United Kingdom
Hi, I had 2 colonoscopies within 3 weeks of each other both coming back inconclusive. I then had to have a bowel resection as they could not rule out cancer and I ended up being diagnosed with Crohn's. So my answer yes it is completely possible.
04-02-2016, 06:13 PM   #5
Jacksik
 
Join Date: Apr 2016
Location: Erie, Pennsylvania

My Support Groups:
I've been having blood in my stool and some mucus. Lots of abdominal pain and cramping. Years this has been the case. Colonoscopy a few days back showed ulcers in the ileum. Biopsies were apparently negative. Sooooo... I go back in a couple of weeks to talk about more testing. The nurse said it could still be Crohn's, that is what the additional testing is for. Is this situation common?

I was just so looking forward to finally having some answers and here I am just as lost as before. Has anyone else had negative biopsies and still had Crohn's?
Did the probe make it through your cecal valve,,any stenosis?
04-03-2016, 01:33 AM   #6
tots
Senior Member
 
tots's Avatar
 
Join Date: Feb 2012
Location: Austin, Texas

My Support Groups:
my story is very much the same.

i know how hard it is. i am so sorry your having trouble.

lauren
__________________


Diagnosed= 1992 and again Feb 2012 Confirmed with
CT enterography May 2015 !!


Waiting for the ok from my Ins company to restart Remicade. Will also start Imuron to get into remission!
I know it's out there somewhere and I WILL find it!


:


Ok, my family Dr told me to cut down on the stress- a husband, 3 kids, and 3 dogs!
04-03-2016, 09:07 AM   #7
DEmberton
Senior Member
 
DEmberton's Avatar
 
Join Date: Jun 2014
Location: York, United Kingdom

My Support Groups:
Can they take biopsies from the Ileum? I thought not as your small bowel is a lot smaller.

The biopsies from my first colonoscopy showed nothing, but the valve wouldn't open so they couldn't see the ileum.
__________________
Diagnosed May 2014
20cm Terminal Ileum and Ileocaecal resection July 2014
125mg Azathioprine
04-03-2016, 08:09 PM   #8
Jacksik
 
Join Date: Apr 2016
Location: Erie, Pennsylvania

My Support Groups:
If the cecal valve won't open,,it needs to be removed, I would think.It's the gold standard for Crohn's disease..it affects the last portion of your small intestines
04-04-2016, 12:45 PM   #9
Scipio
Senior Member
 
Scipio's Avatar
 
Join Date: Oct 2015
Location: San Diego

My Support Groups:
Unlike UC, the ulcers in Crohn's are discontinuous, usually described as "patchy." You can accidentally collect a patch of normal tissue lurking among the ulcers. Thus, it is entirely possible to see an ulcer but end up seeing histologically normal-looking tissue on biopsy. This is why a positive Crohn's biopsy is almost certainly truly positive for the disease, but negative biopsy may or may not be truly negative for Crohn's.
04-04-2016, 09:01 PM   #10
xmdmom
Senior Member
 
Join Date: Jun 2012
Location: New York

My Support Groups:
Do you have the exact wording of the biopsies? Was there any inflammation seen?
Sometimes the pathologists may see inflammation in the biopsy but don't call it crohn's because there were no granulomas seen. However, many (most?) biopsies of Crohn's don't show granulomas so go figure.

If there were ulcers, a biopsy of that area would definitely show some abnormality so either the doctor didn't biopsy the ulcer or the biopsy was not normal.
Reply

Crohn's Disease Forum » General IBD Discussion » Biopsies negative but ulcers in ileum?
Thread Tools


All times are GMT -5. The time now is 05:25 PM.
Copyright 2006-2017 Crohnsforum.com