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Crohn's Disease Forum » Ulcerative Colitis Forum » 6mp (mercaptopurine) ?


12-26-2016, 05:40 AM   #1
NativeBeauty
 
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Location: Columbus, Ohio

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6mp (mercaptopurine) ?

Hello everyone,

I am curious if any of you have been prescribed 6mp (mercaptopurine) ? If so, was it effective? I'm asking because humira alone is not working for me. I have read different posts on different support groups and such, where people have had relief of symptoms and an improvement with 6mp added. Should I mention it to my doctor? I'm thinking about calling him today, speaking with the nurse who then tells him everything. Would it be a good idea to mention this medication? I have been on asacol since I was first diagnosed. It has never helped me. My doctor has known this, yet still prescribes it to me. I take it, however I have never seen any kind of positive effect from it. Thank you for any replies. Xoxo
12-26-2016, 11:24 AM   #2
Ricky_V
 
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Location: Columbus, Ohio
Hi. I have 2 daughters with Crohn's and they are both on 6MP. Julia has been in remission for 8 years on just 6MP. Renee uses 6MP with a Biologic(Remicade) and she is doing well. The best advice I can give you if you live in Columbus is to go see Dr. David Wenzke at Ohio Gastro.
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_________________

Renee (23) dx 9/15 - Status: Feeling Good

Current Meds:
Remicade 7.5mg every 6 weeks
6MP @ 50mg /Day
Omeprazole
Vitamin D2 50000iu /Weekly (Prescription)

Supplements:
Multivitamin
Vitamin D3 1000iu /Day
Organic Apple Cider Vinegar

Failed Meds:
Humira

Gall Bladder removed 4/16

_____________________

Julia (21) dx 6/08 - Status: Remission 9yrs
Current Meds:
6MP @ 100mg /Day

Supplements:
Multivitamin
12-26-2016, 05:42 PM   #3
laura98
 
Join Date: Nov 2015
Location: Chicago, Illinois

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I've been on 10 mg/kg of Remicade and 75 mg of 6 MP together for a while now, and the combination has been working really well for me!
__________________
19 year old female,
Crohns dx: March 2014 at 16 years old,
Past medications/treatment: 5 and 7.5 mg/kg Remicade every 4-8 weeks, Pentasa, EEN nutrition with Boost Plus (10 weeks), Prednisone
Current medication: 10 mg/kg Remicade every 7-8 weeks, 50 mg 6 MP daily, and vitamin D supplement

In remission!
12-27-2016, 02:59 PM   #4
NativeBeauty
 
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I've been on 10 mg/kg of Remicade and 75 mg of 6 MP together for a while now, and the combination has been working really well for me!


Aww, I'm so glad to hear that! I'm on 80mg of humira(bi-weekly). I really want to start 6mp. I've heard more good than bad about it. Humira alone isn't working for me. /: I'm hoping my doctor puts me on 6mp. I'll find out tomorrow
12-27-2016, 04:39 PM   #5
Ricky_V
 
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Location: Columbus, Ohio
From what I understand, 6MP is now commonly used in conjunction with a biologic (Humira, Remicade, Entivio, Etc...) to help prevent generation of antibodies to that biologic. A little surprised that 6MP was not prescribed with your Humira to begin with. If it been 2-3 months and you are not seeing results with Humira you may need to discuss new colonoscopy and switch to Remicade and 6MP. See my doctor referral in previous post.
12-27-2016, 11:56 PM   #6
NativeBeauty
 
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From what I understand, 6MP is now commonly used in conjunction with a biologic (Humira, Remicade, Entivio, Etc...) to help prevent generation of antibodies to that biologic. A little surprised that 6MP was not prescribed with your Humira to begin with. If it been 2-3 months and you are not seeing results with Humira you may need to discuss new colonoscopy and switch to Remicade and 6MP. See my doctor referral in previous post.


I've been on humira just over a year now. I was originally on the normal dosage of 40mg bi-weekly. But after awhile that kinda lost its effectiveness. Especially after I was taken off of it for a week, due to problems with insurance. ): So after that it didn't work as well, my doctor then put me on the double dose of it. And I've been on that for a few months now. He was wanting to put me on remicade or entivio, but my insurance wouldn't cover it.. He had to argue with them for awhile to even get them to cover the double dosage of humira. Idk. I guess I'll figure out tomorrow.
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