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Crohn's Disease Forum » Treatment » Remicade/Infliximab » Remicade hives and skin issues?


04-19-2017, 05:19 AM   #1
73monte
 
Join Date: Apr 2013
Location: niagara falls, Ontario
Remicade hives and skin issues?

I've posted before about this , but really didn't get any replies. I'll try again, as I'm looking for anyone with related experience, or some simple advice.

My Daughter has been on Remicade for about 5 years now. She really hasn't had any negative side effects, and Remicade seems to be working against her Crohn's quite well.

This year she started having intermittent rashes. They come and go, we've tried everything from changing soaps and detergents, to going hypoallergenic.

Today she broke out in hives. This happens from time to time as well, but this time there are several on her face. She's quite upset of course being female, and her face.

She went to the Doctor straight away. She's (Dr.) unsure of the cause, but is suspecting a Remicade reaction or possibly gluten.

I don't want to get long here, so my question is, has anyone had skin reactions, or hives where Remicade was the issue? Could this be a sign of anti-bodies developing?

She's never had any sort of reaction post infusion. These issues seem to arise intermittently, and can be weeks after her last infusion.

I know from previously that this may be uncommon, but I'd really appreciate some advice or input on this. She's calling her GI to try to get in, but that could take awhile.
04-19-2017, 09:39 AM   #2
TammyR
 
Join Date: May 2016
Location: Adelaide, South Australia, Australia
I had four doses of Remicade and it was working brilliantly for my Crohns symptoms but in the six weeks between dose 4 and 5 I developed very, very dry skin with a flaky white rash pretty much all over my body but worst on my back, arms and legs.
At my 5th infusion appointment, my GI cancelled the treatment and has changed me to Humira due to an 'adverse reaction'. My rash felt like ants under my skin, annoying, sometimes itchy but felt yucky and made me feel quite depressed. It took about 8 weeks after the 4th infusion for the rash to go away.
__________________
Tammy
Diganosed - Crohns Feb 2016
MR Small Bowel Study Jan 2016
MRCP 6/16, 7/17 - no change (2 small cysts)
CT Abdomen and Pelvis 10/16 - Acute/Chronic flare distal small bowel with at least two areas of partial obstruction identified.
Started Humira 12/4/17. Previously on Remicade (4 rounds - caused rash), Pentasa, Aza (caused pancreatitis).
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