04-21-2017, 11:07 AM   #1
Forum Monitor
ronroush7's Avatar
Risks vs. benefits?

Earlier this week, they found a squamous cell cancer on my body. This is the second one since November. I don't know if it is a result of imuran or sun. Doctor says I can trying to go off imuran with the option of going back on if I flare. Should I go off or stay on?
04-21-2017, 12:23 PM   #2
Forum Monitor
ronroush7's Avatar
I have decided to stay on it.
04-21-2017, 05:07 PM   #3
Senior Member
Join Date: Aug 2012
Location: Cheshire, England, United Kingdom

My Support Groups:
Can you switch to MTX? From what I have read this does seem to be a common thing - repeatedly finding skin cancers after being on imuran for a long period of time, irrespective of sun exposure. I've read of people finding it on their genitals, which have never had sun exposure. The other thing might be to possibly lower the dose?
04-21-2017, 05:11 PM   #4
Forum Monitor
ronroush7's Avatar
I mentioned it a few months ago and the doctor was reluctant because I have had issues with several drugs. I built up allergies to Remicade, Doxycycline and Flagyl.

04-21-2017, 06:28 PM   #5
my little penguin
Forum Monitor
Join Date: Apr 2012

My Support Groups:
You don't build antibodies to Imuran or methotrexate
They can be stopped or started multiple times without any risk
Biologics are a different story they can't be stopped without a risk of them not working when you restart them

I would talk to your doc
Mtx has a lower skin cancer rate
Then Imuran
DS - -Crohn's -Stelara -mtx
04-21-2017, 06:55 PM   #6
Forum Monitor
Maya142's Avatar
MTX does have a lower skin cancer risk - it is usually considered safer than Imuran by pediatric gastroenterologists. It is being used more and more and Imuran is being used less and less. Imuran also has a higher Lymphoma risk, I believe.

You could try MTX and if it doesn't work for you, you could go back to Imuran.
Mom of M (20)
diagnosed with Crohn's Disease at 16
Juvenile Idiopathic Arthritis at 12
Juvenile Ankylosing Spondylitis at 16

Mom of S (23)
dx with JIA at 14
Ankylosing Spondylitis at 18

Thread Tools

All times are GMT -5. The time now is 01:06 AM.
Copyright 2006-2017 Crohnsforum.com