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Suppository now more pain

Hi I wanted to know if anyone ever had increase in pain after suppository. my son has been taking laxido and sodium picosulphate and still had constipation issues so was prescribed suppositories. last night before taking it pain level was a 9 and evr since has gone up to constant 10 with bad nausea. He had a narrowing at resection site but dr was happy with mri. Im at my wits end cant watch him in the severe pain. his bloods and faecal calprotectin are normal.
 
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