Share Facebook
Crohn's Disease Forum » Books, Multimedia, Research & News » Trends in Epidemiology of Pediatric Inflammatory Bowel Disease in Canada


05-10-2017, 07:43 PM   #1
Lady Organic
Forum Monitor
 
Lady Organic's Avatar
Trends in Epidemiology of Pediatric Inflammatory Bowel Disease in Canada

''Trends in Epidemiology of Pediatric Inflammatory Bowel Disease in Canada: Distributed Network Analysis of Multiple Population-Based Provincial Health Administrative Databases''

http://www.nature.com/ajg/journal/va...jg201797a.html

Abstract

Objectives:

The incidence of pediatric-onset inflammatory bowel disease (IBD) is increasing worldwide. We used population-based health administrative data to determine national Canadian IBD incidence, prevalence, and trends over time of childhood-onset IBD.

Methods:

We identified children <16 years (y) diagnosed with IBD 1999–2010 from health administrative data in five provinces (Alberta, Manitoba, Nova Scotia, Ontario, Quebec), comprising 79.2% of the Canadian population. Standardized incidence and prevalence were calculated per 100,000 children. Annual percentage change (APC) in incidence and prevalence were determined using Poisson regression analysis. Provincial estimates were meta-analyzed using random-effects models to produce national estimates.

Results:

5,214 incident cases were diagnosed during the study period (3,462 Crohn’s disease, 1,382 ulcerative colitis, 279 type unclassifiable). The incidence in Canada was 9.68 (95% CI 9.11 to 10.25) per 100,000 children. Incidence was similar amongst most provinces, but higher in Nova Scotia. APC in incidence did not significantly change over the study period in the overall cohort (+2.06%, 95% CI −0.64% to +4.76%). However, incidence significantly increased in children aged 0–5y (+7.19%, 95% +2.82% to +11.56%). Prevalence at the end of the study period in Canada was 38.25 (95% CI 35.78 to 40.73) per 100,000 children. Prevalence increased significantly over time, APC +4.56% (95% CI +3.71% to +5.42%).

Conclusions:

Canada has amongst the highest incidence of childhood-onset IBD in the world. Prevalence significantly increased over time. Incidence was not statistically changed with the exception of a rapid increase in incidence in the youngest group of children.
__________________
''UC-like Crohn's'' since 2001:
on: 25mg 6-MP (purinethol)+ B12 shots
minor hands/wrists chronic arthritis since 01/2013

Diet: ''IBD-AID'' : http://www.nutritionj.com/content/13/1/5+ organic food only
suppl Curcuminoid extract, Inulin,psyllium, apple pectin, Vitamin D

past meds:
pred 50mg, 5-ASA, cortifoam, Imuran (failed) Purinethol (success) methotrexate (failed CD and arthritis).
05-11-2017, 06:26 AM   #2
Pilgrim
Senior Member
 
Pilgrim's Avatar
 
Join Date: Jul 2014
Location: Ontario

My Support Groups:
We definitely fit this mold. Our daughter was diagnosed at 3 and it was 2013. Canadian. Our GI had confirmed this trend. He said it used to be rare for a child to be diagnosed with Crohn's at such a young age but unfortunately it is much more regular now.
Reply

Crohn's Disease Forum » Books, Multimedia, Research & News » Trends in Epidemiology of Pediatric Inflammatory Bowel Disease in Canada
Thread Tools


All times are GMT -5. The time now is 07:32 AM.
Copyright 2006-2017 Crohnsforum.com