I'm New to the forum, but have had Crohns since 1971 (46 years). The Crohns started during a time of stress at work. Both of my twin daughters have Crohns also (started the last year of college). I had emergency surgery at the time of diagnosis and 3 since for adhesions from the original surgery. I have been on multiple different drugs, including Sulfa, Imuran, Budesonide (now stopped with side effects) and will be restarting Imuran shortly. I was on Remicade for 13 years and have now switched to Humira. Most of the time I have been in remission and working steady, but about to finally retire.:thumleft: