Does anyone here have a history of intestinal fistula? I have been on Remicade for crohns since seven years ago and my GI just increased the dosage to 10mg every 6 weeks to see if it helps closing the fistula. According to the MRI, I have a fistula between ileum and sigmoid. I am scared bec I read it can put the body into a septic shock. I am seeing a colorectal surgeon in four weeks. I am also on 6MP since four months ago. My GI is not sure how long the fistula has been there. Is there a chance that increased dosage of Remicade closes the fistula? Or can Entyvio or Humira help? I don't want to have surgery. Any experience or info that you can share will be appreciated.