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Biological therapies

Biological Therapies for Treatment of Crohn's Disease

Biological therapies for the treatment of Crohn's Disease (CD) are among the newest therapeutic agents to be used in Crohn's Disease treatment.

Biological therapies work with the body's Immune System to treat disease. For example, one type of biological therapy utilizes monoclonal antibodies that inhibit the activity (neutralize) Tumor Necrosis Factor (TNF). TNF regulates the immune system, and appears to play some role in inducing Inflammation in disorders such as Arthritis and IBD.

Biological therapies carry serious risks of side effects, including Immunosuppression, increasing a patient's susceptibility to infection.

Current biological therapies approved for use in moderate to severe IBD include Humira, Remicade, Cimzia and Tysabri. Stelara, currently approved for treatment of Psoriasis, is being evaluated for use in Crohn's Disease (Phase III Clinical Trials).


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02-15-2012, 12:50 PM   #1
Trysha
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Hello Rebecca,
Thank you for the information on biological agents, it is very interesting.
Trysha
02-16-2012, 12:08 AM   #2
ctrl z
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Is it supposed to say "reducing" instead of "inducing" inflammation?
02-16-2012, 04:32 AM   #3
DustyKat
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No, it is mean't to be inducing.

TNF appears to cause inflammation in IBD and the biologics stop/block them from doing this.
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Mum of 2 kids with Crohn's.

Sarah [22] Ileal CD
Ileocecectomy 10/07/2006
Imuran 50mg
Vit D, Psyllium Husks

Matt [21] Ileal CD
Ileocecectomy 07/04/2011
Imuran 75mg
Pentasa 2grm
B12, Vit D, Zinc, Magnesium, Turmeric, Psyllium Husks
02-16-2012, 01:20 PM   #4
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Ohhh... I gotcha. Thanks
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