Biological Therapies for Treatment of Crohn's Disease
Biological therapies for the treatment of Crohn's Disease (CD)
are among the newest therapeutic agents to be used in Crohn's Disease treatment.
Biological therapies work with the body's Immune System
to treat disease. For example, one type of biological therapy utilizes monoclonal antibodies that inhibit the activity (neutralize) Tumor Necrosis Factor (TNF)
. TNF regulates the immune system, and appears to play some role in inducing Inflammation
in disorders such as Arthritis
Biological therapies carry serious risks of side effects, including Immunosuppression
, increasing a patient's susceptibility to infection.
Current biological therapies approved for use in moderate to severe IBD include Humira
, currently approved for treatment of Psoriasis
, is being evaluated for use in Crohn's Disease (Phase III Clinical Trials).
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