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Hypochlorhydria

Hypochlorhydria is low stomach acid. In people with Crohn's Disease, this is usually caused by acid blocking drugs such as proton pump inhibitors (PPIs) or H2-receptor antagonists (H22-RAs) or gastritis. As vitamin B12 needs high levels of stomach acid to be separated from protein, this can result in vitamin B12 deficiency. Hypochlorhydria can also increase the risk of developing Small Intestine Bacterial Overgrowth.[1]

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