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Peripheral Neuropathy

Peripheral Neuropathy is a condition in which there is damage to the Peripheral Nervous System (PNS). Sometimes damage to the PNS can affect the Autonomic Nervous System (ANS).

Contents


Symptoms of Peripheral Neuropathy
Symptoms of Peripheral Neuropathy can range from Mild to Severe:
- Numbness [6]
- Tingling [6]
- Pain [6] / Neuropathic Pain [4] (For more information on Chronic Pain check out the NIH Chronic Pain Website HERE)
- "Pins and Needles" Sensation
- Burning Sensation
- Itching[9]
- Sensation of Pain with Touch / Allodynia (Pain to Something that Should Not Normally Cause Pain)
- Muscle Weakness [6]
- Muscle Cramping
- Dizziness / Loss of Balance / Falling
- Paralysis
- Impaired Food Digestion
- Impaired Sexual Function
- Inability to maintain Blood Pressure (BP)
Causes of Peripheral Neuropathy
Peripheral Neuropathy can be caused by multiple factors (this is not an exhaustive list):
- Injury
- Autoimmune Disease
- Guillain-Barre Syndrome
- Diabetes
- Alcoholism
- Vasculitis / Blood Vessel Inflammation / Blood Vessel Disease
- Cancer / Tumor
- Toxin Exposure
- Exposure to Heavy Metals or Certain Chemicals
- Infection
---- Lyme Disease
---- Shingles (Herpes Varicella Zoster Virus)
- Medications / Certain Antibiotics / Chemotherapy Drugs
- Nutritional, Vitamin or Supplement Effects
---- Vitamin B1 / Thiamine Deficiency [1]
---- Vitamin B3 / Niacin Deficiency [1]
---- Vitamin B6 / Pyridoxine Deficiency [1][3]
or Excess [3]
---- Vitamin B12 Deficiency [1][6]
---- Vitamin E Deficiency [1]

Treatment for Peripheral Neuropathy

Pain Medication
Opiates / Narcotics
Anti-Inflammatory Treatment
Aspirin
Corticosteroids [5]
COX-2 Inhibitors (i.e. Celebrex)
Epilepsy / Anti-Siezure Medication
Depakote (Valproic Acid) [8]
Neurontin (Gabapentin) [7]
Topamax (Topiramate) [8]
Anti-Depressant Medication
Amitriptyline [8]
Cymbalta (Duloxetine)[8]
Effexor (Venlafaxine)[8]
Pamelor / Aventyl (Nortriptyline) [8]
Supplement / Non-Drug or Alternative
Capsaicin - Extract from Peppers
TENS
Biofeedback
Vitamin C
Vitamin E

References

1. http://www.ninds.nih.gov/disorders/p...neuropathy.htm

2. http://www.ninds.nih.gov/disorders/c...ronic_pain.htm

3. http://www.google.com/url?sa=t&rct=j...5kJHJNmxFD-Lvw

4. Translational investigation and treatment of neuropathic pain. Molecular Pain. 2012; 8(15): doi:10.1186/1744-8069-8-15 http://www.molecularpain.com/content...-8069-8-15.pdf

5. http://peripheralneuropathycenter.uc...nt/index.shtml

6. Types of Peripheral Neuropathy - Systemic / Metabolic. The University of Chicago. Accessed June 2012. http://peripheralneuropathycenter.uc...utrition.shtml

7. Neurontin (Gabapentin). Pfizer Inc. Accessed June 2012. http://www.pfizer.com/products/rx/rx..._neurontin.jsp

8. Selph S, Carson S, Fu R, Thakurta S, Low A, McDonagh M. Drug class review: Neuropathic pain. Update 1 final report. Prepared by the Oregon Evidence-based Practice Center for the Drug Effectiveness Review Project. Oregon Health & Science University. Portland, OR. 2011. Available at:
http://derp.ohsu.edu/about/final-document-display.cfm

[pos]9a[/pos][9] http://dfwneuro.com/?page_id=5

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