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Psoriasis

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Psoriasis

Psoriasis is a Chronic skin Inflammation condition which causes an exagerrated growth of the skin.
Psoriasis has skin characteristics called "Plaques" typically located on the elbows, knees, scalp and back. These Plaques have a characteristic appearance that typically includes:
  • Flaking
  • Irritation
  • Redness
  • Scaling

Psoriasis can be caused by many factors which cause an inappropriate response of the Cellular Immune System.[3]

Psoriasis is not contageous (transmissible to others).

Gene Mutations causing Psoriasis and Crohn's Disease

People with Psoriasis can sometimes have Crohn's Disease as certain gene mutations can increase susceptibility for both diseases.[3]
Gene mutations known to increase the likelihood for both Psoriasis and Crohn's Disease (CD) include:

Treatment for Psoriasis

Psoriasis treatment can include can be directly applied to the skin (topical) or can be a medication used systemically.
Topical Treatments for Psoriasis
- Salicylic Acid Cream
- Ointments containing Coal Tar
- Steroid or Cortisone containing Creams
Systemic Treatments for Psoriasis
- Cyclosporine
- Methotrexate
- Humira
- Remicade
Light Therapy (Phototherapy) for Treatment of Psoriasis

Phototherapy, or exposure of the skin to Ultraviolet Light has been shown to be an effective treatment for Psoriasis.

Also, Vitamin D can play an integral role in the management of psoriasis.[1]

References

[pos]1a[/pos][1]. http://www.ncbi.nlm.nih.gov/pmc/arti...e0304_0220.pdf

[pos]2a[/pos][2]. Psoriasis. (2011) A.D.A.M. http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001470

[pos]3a[/pos][3]. Ellinghaus D, Ellinghaus E, Nair RP, Stuart PE, Esko T, Metspalu A, Debrus S, Raelson JV, Tejasvi T, Belouchi M, West SL, Barker JN, Kks S, Kingo K, Balschun T, Palmieri O, Annese V, Gieger C, Wichmann HE, Kabesch M, Trembath RC, Mathew CG, Abecasis GR, Weidinger S, Nikolaus S, Schreiber S, Elder JT, Weichenthal M, Nothnagel M, Franke A. Combined Analysis of Genome-wide Association Studies for Crohn Disease and Psoriasis Identifies Seven Shared Susceptibility Loci. The American Society of Human Genetics. 2012; 90(4): 636-647. http://www.sciencedirect.com/science...0292971200105X

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