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  1. M

    Intestinal Th17 Subset is Associated with Inflammation in Crohn’s Disease and Activated by AIEC

    Good article. Thanks for sharing. Interesting that they mention the effectiveness of certain biologics. Skyrizi is more effective than Stelara. Both Stelara and Skyrizi block IL23 but Skyrizi zeros in on a subunit, P19.
  2. M

    Daily consumption of fruit/vegetables in OECD countries and crohn's disease prevalence.

    Wow, this is very interesting and completely contradicts the current dogma.
  3. M

    Intestinal ultrasound for monitoring IBD

    Following your post, Artheta, here is a great discussion: Intestinal Ultrasound Discussion with Dr. Michael Dolinger https://www.propelacure.org/news
  4. M

    Continuation of the discussion with Drs. Mark Davis and Vincent van Unen of Stanford University

    Not yet. Their timeline was at least two years. I suspect it will take longer.
  5. M

    Discussion with Dr. Mark Sundrud

    Kiny, thank you for your opinion. I always find what you have to say very interesting, thought provoking and valid. Dr. Sundrud mentions he believes that only 10% of folks diagnosed with Crohn's have the issue he discussed. Isn't it possible that for the vast majority, his findings won't apply...
  6. M

    Food Additive

    Stay tuned! We interviewed Dr. Chassaing and will be posting it in January. Compelling stuff! He has clearly shown that certain emulsifiers can cause trouble, allowing bad bacteria to take hold.
  7. M

    Watch Dr. Brian Coombes discuss his research into the possible link between Adherent Invasive E-coli and Crohn’s

    I agree with you, Wildbill, of the potential of FMT, though this report from Borody is anecdotal. It is unfortunate that more robust random controlled studies have not been done on Crohn's patients. We need to control for disease activity, where it is located, the existing microbiota, the number...
  8. M

    Watch Dr. Brian Coombes discuss his research into the possible link between Adherent Invasive E-coli and Crohn’s

    Propel a Cure presents Dr. Brian Coombes, from McMaster University in a question-and-answer format, Zoom call where he discusses his exciting work uncovering the possible role of Adhesive Invasive E-coli (AIEC) in Crohn’s disease.
  9. M

    Rna Based drugs for crohns

    Thanks for posting this! Very interesting and hopeful! Yay for science!
  10. M

    Continuation of the discussion with Drs. Mark Davis and Vincent van Unen of Stanford University

    In the video, we continue a conversation our board recently had with Dr. Mark Davis and Dr. Vincent van Unen of Stanford University, who are seeking to identify the T cells specific to disease driving antigens in Crohn's. Propel a Cure is a proud sponsor of this project. Don't miss this rare...
  11. M

    New E. coli study

    Kiny, you always do a great job of explaining the mechanisms. Thank you!
  12. M

    QuBiologics new phase 2 trial recruiting soon

    They have all the plans for the next trial which will be bigger and international, but the thing stopping it? Money! Or lack of.... they need partners and I am guessing it has been difficult to find them.
  13. M

    Supporting research using Organoids

    Firstly, I want to thank the creators of this forum because when my son was diagnosed in 2014 and very, very scared I shifted into mommabear mode, and found hope here with all of the research that was posted, so much more than what I could find elsewhere. As a result, I got drawn into the MAP...
  14. M

    Making SCD yogurt using lactose free milk and can I use starter from Trader Joe’s organic yogurt?

    Has anyone made it with lactose free milk? Are there potential problems with it? I looks like ALL the yogurt from Trader Joe’s contains bifidus which according to Breaking the Vicious Cycle is illegal. What to do? Does it really matter?
  15. M

    New vaccine possibility (not MAP)

    My son’s symptoms first showed up in the mouth. But we didn’t know what it was and he lived with a misdiagnosis and worsening condition for nearly a year. Turns out his mouth was a reflection of his entire digestive tract, and culminated in anal fistula formation. But, more inflammation and...
  16. M

    New vaccine possibility (not MAP)

    Kiny, the formation of granulomas makes sense and it would seem to clearly indicate an infection by a pathogen. But what about the people who don’t have granulomas? Can we still say the same thing? Thanks!
  17. M

    New vaccine possibility (not MAP)

    I understood that it was at times when the immune system is weakened, by stress or a bad cold, etc., and with older people whose immune system is no longer as robust. However I just read yesterday about the cattle vaccine being created at Washington State showing that in MAP, like in TB in...
  18. M

    Mapping the gut

    Something to keep an eye on...
  19. M

    New vaccine possibility (not MAP)

    Yesterday I learned of a very interesting company called Inflammatix. They have created several diagnostic tests using the host immune response to read the Immune system and diagnose specific diseases like sepsis, TB, etc. They can differentiate between viruses and bacteria, and latent and...
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