Crohn's Disease Forum » Treatment » Clinical Trial: Filgotinib anyone?


11-04-2018, 01:50 PM   #1
Crohnsmomof3
 
Join Date: Oct 2013
Location: Indiana

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Clinical Trial: Filgotinib anyone?

Is anyone on Filgotinib, a clinical trial medication? I have been on this trial for a few months and it appears I may have been on placebo as I have gotten worse. I am switching to the real drug in about a week (switching to the extended trial because of worsening of symptoms). Was wondering if anyone has tried this medication and what benefits they have seen. I do love that it is a pill and not an injection. Thanks!
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Leslie

Diagnosed: 2004
Abcess: 2011
TI resection 2013 (60 cm of small bowel)

Current: Filgotinib (clinical trial), Questran, B12 injections, metoprolol, sertraline

Past medications: stelara, methotrexate, pentasa, remicade, humira, cimzia, imuran, prednisone, entocort, 6mp
Adverse reactions: Entyvio, Remicade, Humira, Cimzia, Imuran, 6MP

Diagnoses: Crohn's Disease, Iron deficiency Anemia, B12 Anemia, Osteoporosis, Migraines, Anxiety
11-04-2018, 03:45 PM   #2
Maya142
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My daughter is the one who has Crohn's but I wanted to say that I have heard lots of good things about JAK inhibitors!! They're next in the pipeline for both Crohn's and Arthritis. Tofacitinib or Xeljanz is the one that was just approved for both UC and Psoriatic Arthritis (and has been approved for RA for years).

My daughter (who has both Crohn's and Ankylosing Spondylitis) has failed most biologics, like you. The next drug we try if her current treatment fails would probably be a JAK inhibitor. I have heard good things about them from both her GI and the multiple researchers we see for her arthritis (her AS is pretty severe, but thankfully her Crohn's isn't too bad).

Hang in there - I would guess you're on the placebo. Hopefully you'll be given the real drug soon!!
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Mom of M (20)
diagnosed with Crohn's Disease at 16
Juvenile Idiopathic Arthritis at 12
Juvenile Ankylosing Spondylitis at 16

Mom of S (23)
dx with JIA at 14
Ankylosing Spondylitis at 18
11-04-2018, 08:25 PM   #3
Crohnsmomof3
 
Join Date: Oct 2013
Location: Indiana

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That is good news! I am hopeful that it will help, it figures that I got the placebo! I had an 80% chance of getting the actual drug...but alas it will be soon. I have been traveling to Indianapolis every two weeks for the last number of months and it is three hours away. It is not fun! But, in a month it will switch to every three month. That will be great. I am hoping this works!!
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