Crohn's Disease Forum » Treatment » Prednisone/Entocort » Prednisone side effects?


 
06-02-2012, 09:47 PM   #1
KitKat08
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Prednisone side effects?

So after my second trip to the ER in a week, the doctor was able to get ahold of a GI doctor and they decided to put me on a prednisone taper
40mg- 7 days
30mg- 7 days
20mg- 7 days
15mg- 7 days
10mg- 7 days
5mg - 7 days

I'm on day two and was wondering if these were normal side effects of taking prednisone.
Firstly I've have horrible mood swings ( I'm normally moody but I caught myself flipping out at my 6 y/o stepson just for running in the house, and I'm extra grouchy at my boyfriend )
I am really sweaty/ hot all the time. I live in Oregon, it's almost always cold here!
I'm really hungry. Usually I go until dinnertime with out being the least bit hungry now it's like I wake up hungry and want to eat!
I'm not complaining about this one, but my legs usually have these ugly red dots upand down, and now they are magically gone!
Lastly I find myself not tired at night. My usual bedtime is 10:45/11:30. I was up past 1 last night :/.
Thanks for any help!!
Take care, Ashley
06-03-2012, 12:01 AM   #2
adomako69
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Hey Ashley
My name is Anthony and I am new to this forum too. Unfortunately, I have had Crohn's for over half my life, or about 13 years. I have been on prednisone to control flare ups more times than I can count, and every side effect you are describing usually happens to me too. Mostly, the steroids give me really bad mood swings, agitation, weight gain, always sweating, very hard to sleep at night - which I have found taking them early in the morning does help with this. Also, they make me eat like crazy, usually I'm not hungry until the evening but on prednisone, I constantly feel like I am starving, which for people with our disease, is not really a bad thing. Usually after a week or so they do get slightly better as your system adjusts but generally, I experience all of these until I have been off them awhile. Just make sure you explain to your boyfriend that you are on medication that messes your body and mind up and that will definitely help. Well, I hope this helps, good luck!
06-03-2012, 03:55 AM   #3
Grumbletum
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Hi Ashley and Anthony :-) The lovely Pred, huh? Gotta love it and hate it! I was on it for 6 months and tapering off was hard. Interesting what you said about the dots on your legs, Ashley. I started getting a few itchy coin shaped patches on my legs a few months before my stomach issues started. They too disappeared when I started on Pred, but flared up badly again recently and turns out it's Psoriasis.
Might be worth mentioning to your GI.
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06-03-2012, 07:38 AM   #4
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I just started Pred for the first time today, 30mg 2 weeks then tapering down at 5mg less for 5 days each so 39 days total.
I have noticed a slight improvement in joint pain, and am quite hungry for the time of day, but other than that, nothing yet. No improvement in abdo pain or exhaustion (I really want to go back to sleep actually!).
I take mine at 8am as directed by my Dr.
I get a heat/sun rash, so if the weather improves here, it would be interesting to see if it comes back or not.
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06-03-2012, 08:33 AM   #5
nikimazur
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Prednisone also effects your hormone levels, in addition to tackeling inflammation. It works on specific hormones that impact your mood levels... Ina similar way that athletes take anabolic steroids and have roid rage...it's almost a form of mood swings associated with Pms for your hormones are elevated then. So even though it's a pain in the bum, it's normal to feel "off" or miserable haha when on pred
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Past meds: Pentasa, Lialda, Prednisone, Entocort, Asacol HD, Prilosec, Lomotil, Lotronex, Nexium, Myfortic, Humira




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06-03-2012, 12:31 PM   #6
KitKat08
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Thank you all for your replies!
I've noticed improvement with joint pain as well, I was taking oxycodone all last week for pain and I haven't had to in the last three days! However this morning I slept in way past the time I've been taking pred and my joints were stiff again
I've never thought of Psoriasis, I am working on getting some sort of health insurance so I can see a GI doctor.
06-03-2012, 01:53 PM   #7
nevilletanner
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HI

i have been on PRED this year, but luckly my GP agreed to me tapering of it very quickly so i was only taking them for about two months in total.

i describe them as a wonder drug / hell in a pill , i can never descide which description to use, there really good at helping us crohnies but the side affects are dreadfull.

what i noticed was :-

HUNGER - to the extent that six meals wasnt enough, i even debated fighting the dogs for there food lol

MOOD SWINGS - yep i was losing it over really stupid things like a silly computer game

EMOTIONAL - watch a stupid girly film and i can feel myself getting ready to blubber, normally i laugh and get the tissues for the wife.

ENERGY - yep i cant sleep and when im up i want to be active all the time.

the other thing i noticed was a bit personal but what the hell - sex, i wanted it much more than normal but when it came down to it - it was more like a chore that i would try and get out off in anyway i could. (headache tonight - sorry).

all of these rapidly disapear when i stoped taking them

regards
N.
06-05-2012, 01:19 PM   #8
KitKat08
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Another question if any could answer. I've been battling a cold and finally got over the sore throat and just mainly have congestion. However this morning I woke up with my face semi swollen and right under my chin/ down the sides of my throat/ around my neck and half way down my back hurts like I have a bruise but I don't. It's really sensitive to touch but swallowing doesn't hurt. But it's kind of bothers me.
06-06-2012, 01:41 AM   #9
Aura
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I would make an appointment with your doctor to get it checked out. It's not a normal reaction, and I would try and get it sorted as soon as possible. Good luck and keep up posted.
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06-13-2012, 10:10 PM   #10
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Hi..your side effects sounds pretty normal.. I was on prednisone for an extended amount of time ...it caused me to have terrible "moon face", I became scatter brained and my stomach got damaged..every drug has got its side effects
06-13-2012, 11:10 PM   #11
KitKat08
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now that I've been on it for almost 2 weeks I have gotten used to the side effects.. No longer chewing me boyfriend or son out (heehee) but horrible horrible insomnia but then I take the next dosage and I'm fine for the day. I've noticed I've gained a bit, even though I havent been eating too terrible. but I think I have the moon face :/
06-13-2012, 11:26 PM   #12
AshleyB85
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I've been on Prednisone for the past 4 weeks. I finally got over the emotional side effects (I was crying every day) about two weeks ago. Moon face hit me this week. Gained about 15 lbs so far, know that I will lose it when I'm finally done with them. The heat thing is what is killer for me. I have to be at 68 degrees F or I'm sweating. My family is cold in the middle of June. Insomnia is normal. I was up for 40 hours straight before I finally got some sleep last night. I started taking 60 mg of Prednisone, so at first, I would get a huge burst of energy when I took it. I'm down to 20 mg now, but I think my symptoms are coming back, so I'm going to talk to my doctor about going back up to 30 for the time being. Not sure about the back hurting, but I've noticed more joint pain recently.
06-14-2012, 12:13 AM   #13
skippy111
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Sweating, hunger, joint pains, yup, those are normal side effects,

My knees ache , I eat like a horse, I sweat alot, but I am back up to close to my normal weight.

Prednizone is an anti-inflamatory, it will make you hungry as it deals with your inflamation, drink plenty of water or juice, if you are sweating it means the prednizone is doing it's job and you need to watch you dont get dehydrated.

I was on 60 mg from the day I was in the ER (April 18th) untill Saturday (June 9th)
when I went to see my GI Dr for a follow up on friday the 8th, he told me to start dropping down by 5mg per week..

I noticed my right foot is cramping and my knees ache. I am sleeping a little bit more because I take my colonzapan at night to wind down and fall asleep.
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Check to see if any of the meds you are taking can intereact with another, just go to the Drug interaction section, it is free! http://www.drugs.com/

Crohn's /Anemia DX in 1991
Aspbergers/Depression/ADHD DX 2001

Past meds for crohn's
Prednisone/Azulfadine

Recent Meds While in Hosp for Crohn's/Depression
Flagyl/Cypro,Zofran Protonix, Prednisone, Lovenox
Celexa,Kolonopin, Ritalin
Current meds:
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06-14-2012, 10:08 AM   #14
StarGirrrrl
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I'm also approaching the 2 week mark, nothing too bad so far but can be hard to cope with the moods, skin isn't looking good, gained water weight (I need to lose not gain) and some bouts of insomnia- nothing like my usual insomina, am not sleepy at all but wide awake and buzzing lol.

Dissapointingly overall my symptoms are not improving- it's like one thing is a little better but another still flares very badly (I don't expect to be symptom free by any means, but nor do I expect to flare so badly while being "treated"). I am still needing the same amount of pain relief and still sleeping all day. The biggest change is I have colour in my skin and I feel alot brighter- but what good is that really, I can't do any more than before Pred and it doesn't out weight the side effects for sure.

Will have to see I suppose what the post trial blood results say.

I start tapering down in 2 days, so 27 more and I am done with pred!!

What will happen next I don't know since they asked me to consider Aza long term "if I get on ok with the Pred". Don't even know if Aza would work if Pred hasn't. And I would be willing to do a second Pred trial at a higher dose, but not for 39 days, no way, would have to be a very short high dose trial for me to agree.
06-14-2012, 11:24 PM   #15
skippy111
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I was on 60 mg of prednizone between april 18th and june 8th, now I am tapering by 5mg per week.

I was given 60 mg of Pred through my IV in the ER, it was like the Drs knew what was going on just by the looks of the fistuala and my history of chrons.

when the nurse told me how much he was giving me I knew something was up even before the Surgeon came and introduced himself.

once they got me settled in my room, they gave me the Protonix, the Flagyl and Cipro, and the Zofran. It is their policy to give everyone the Protonix to thin the blood and prevent clotting.

the amount of prednizone your body will need to fight the inflamation all depends on how bad the inflamation is.

I expect that as I get lower and lower on the prednizone I will eventually be dealing with side effects,
06-15-2012, 01:16 AM   #16
Irene3
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By what iv noticed on this forum, everyone gets all these side effects, and a lot of them can get worse as you wean. Esspecially if your on it for months. I'm down to 10mg, for another week and a half, then 7.5, then 5- etc, at 2 week intervals. My fingers I noticed this morning are finally back to normal, but still have the moon face. I'm hoping at 7.5-5 it will be back to normal. Search 'pred taper' and things like that if your unsure about symptoms. Best wishes
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06-15-2012, 01:29 AM   #17
skippy111
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I had been having a good day other than my achey knees and stiff legs, but then i got an email from the representitive who is processing my charity care//medicaid paperwork at the hospital in which she expressed an opinion which was totally uncalled for, it really upset me even tho I know she is not the one making the descision, she is just processing the forms... so today I let something insignifcant set off a side effect..

I get sad for no reason at all, that is a combination of the depression and a side effect of the prednizone. My Psychotherapist told me that I might benefit from a mood stablizer but after talking with the Psychiatrist she put me at ease when she assured me I wouldnt be getting the zombie pill because mood stablizers interact with the adderall...

I notice too my right eye kinda throbs a bit but not anything to where it is any source of major discomfort.... i am bracing for it tho, once i get further down with the prednizone..
06-15-2012, 01:32 AM   #18
afidz
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When I was on prednisone, it was literally the worst month of my life. especially the first couple of weeks. I was sweating so bad at one point that I had to towel dry my hair at work becasue it was dripping everywhere. I had really bad restless legs syndrome and never slept (partially because I was so hot all the time) and I ate like a cow and gained weight really fast. Its a good drug as far as dealing with a flare up, but the side effects are just aweful
06-15-2012, 01:38 AM   #19
skippy111
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ugh! yeah the sweating,
and I ate a whole pack of pecan shortbread cookies, 4 yogurts, 2 bowls of applesauce with banannas and blueberries, and a little bit of cottage cheese, and that was my late night snack... Im still hungry but not going to eat anything...
06-15-2012, 07:30 PM   #20
Aura
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I started out on 40mg pred and I was on that until I started Humira when I went to 20mg. As of last Thursday I am now 15 and go to 10 this Thursday. I got the moonface - but I still am not hungry and have no desire to eat. I make myself eat cause if I dont then my diabetes plays up. I have essential tremors - but yesterday I shook all day more than I normally do. I flew off the handle for no good reason - apart from I had been in pain all day in my guts. I had taken tramadol throughout the day to manage it, as well as buscopan and panadol. I just wonder why I am not hungry, and so many people seem to have a desire to want to eat on pred...
06-15-2012, 10:07 PM   #21
Hobbes650
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Second time on Prednisone now, at 40mg/day. Been on that for two weeks and will taper down when I get the entocort. First time I used Prednisone was 26 years ago, and I'm noticing the same effects:

1) jittery and mood swings. I get restless and moody and find it hard to use spoons, write, and button shirts. Not so bad this time around, but definitely noticeable
2) moonface. Just started noticing it today. Again, not as bad as before
3) skin acne. Actually cleared up right away, but then after a week or so started to get a mild case again. Same pattern as before.

Luckily I am tapering off once my entocort arrives so this won't last too long.

Hobbes
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Ulcerative Colitis 1986
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Last edited by Hobbes650; 06-16-2012 at 12:37 AM.
06-16-2012, 12:36 AM   #22
AshleyB85
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I've noticed that when I drive, if I have my foot on the brake, that my leg will shake. Could be an effect of the steroids.
06-16-2012, 05:54 AM   #23
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anyone else ever felt really crappy after starting to taper off the pred?

After switching down from 20mg to 15mg a few days ago I've been getting a few headaches, bit of mild dizziness on occasion, and also a sore throat. My bowel movements still seem fine though.

I'm not sure if it is the pred that is doing this or the azo - but I starting taking azo 3 weeks ago and have had no problems at all up until I tapered the pred, so I tend to think it is the pred withdrawal symptoms doing this rather than the azo, unless the pred was masking the effects in some way? Will see what happens when I taper the pred again as Im down to 10mg next week.
06-16-2012, 09:10 AM   #24
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I have been on 20mg of prednisone for about 3 years now. Seem to keep my symptoms under control and the side effects are there, but not too bad. I would love to and have tried to taper, but when I do things start acting up. I think keeping hydrated helps a ton!
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06-16-2012, 11:37 PM   #25
skippy111
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I've noticed that when I drive, if I have my foot on the brake, that my leg will shake. Could be an effect of the steroids.
I think so, Resless leg syndrome is one of the side effects too.

Today I started with 50 mg, so im down 10mg from my original 60mg

I noticed i am a little irritable with my mother and that is bothering me because I know she is just asking things out of concern but she asks me things about appointments and stuff and I tell her I dont know off the top of my head I have to look in my calendar.. we go to some of the same things together with eastern star and I tell her she needs to start writing them in a callendar to put in her purse too instead of writing them on the callender in the kitchen...

it upsets me when I get cranky with her and today i was nearly in tears over it.
06-17-2012, 10:42 AM   #26
StarGirrrrl
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Started tapering today, hunger and moods seem a bit more settled.
24 more days and I am done, not really working anyway so no point in me taking such harsh drugs!
06-17-2012, 01:51 PM   #27
skippy111
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with the 60 mg, I was eating like a horse, today I started with 50 mg, my appitite is fair.
my leg shakes, gets stiff, joints are starting to hurt more, and my feet cramp when i lay on the couch. Cranky as hell,
but, i haven't been exactly getting my Daily nutrients like I had been either, so maybe it is a combination of the decrease in prednisone and lack of nutrients.
06-18-2012, 01:10 PM   #28
SarahAnne
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On day 7 of a 12 day dose pack. I hate pred. I love pred. I hate pred.

I get the restless leg with higher doses of prednisone, and my joints start to ache if I taper too fast after being on high doses.

The mood swings are the worst for me. I rage all day, and then cry all night about how terrible I've been. I yelled at the dog last night for drinking her water too loudly when I was watching t.v.

I would be done with it forever if it didn't help so much when I needed it.
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Dx'd Crohn's April 1996
Bowel Resection w/appendectomy Oct 1996
Gallbladder removed Nov 2005
4 procedures in March/April 2010 to remove a kidney stone
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Dx'd Pancreatitis July 2011
2nd bowel resection 10/12/11 - I have 130cm of small intestines left!
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06-18-2012, 03:24 PM   #29
lizzy16
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I've been taking Pred since October last year, I could never wean off it because the Asacol they also gave me never worked and I'd get horrible withdrawal symptoms - started on Aza last month and I am tapering the Pred down once again. I'm doing much better this time around with the weaning, I jumped from 40mg to 30 to 20 in two weeks, big tapers (I thought my GI was crazy!) but no withdrawal! I'm currently at 20mg and have to stay here for 2 more weeks and then taper by 5mg each week, hopefully off the stuff for good by mid July!

I've had the "moon face", pimples and weakened joints (they only hurt when I exercise eg squats and lunges really kill my knees). I don't really have mood swings but I do get emotional at silly things (watching TV, etc). I used to get night sweats really bad but they've gone away as my inflammation has been reduced.

It is great for getting rid of the inflammation but I'll be so happy to see the end of Pred!
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06-18-2012, 03:27 PM   #30
lizzy16
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Oh and I've been taking a calcium supplement which is important as long-term Pred use can affect your bones - another wonderful side effect!
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