Crohn's Disease Forum » Treatment » Imuran/Azathioprine/6-MP » Imuran/Azathioprine and Diarrhea

12-27-2011, 08:20 PM   #1
Join Date: Apr 2011
Location: Georgia
Imuran/Azathioprine and Diarrhea

One week into Azathioprine and I have my fingers crossed. One question I had, though, is about the "possible" side effects, especially diarrhea. Has anyone experienced this? If so, did you continue taking Azathioprine and the D went away? Like many others here on this forum, I have a very sensitive GI tract, and I can just see this as a possibility for me.
DX March, 2011 - Symptoms 5 years prior
Azathioprine (Imuran) - 200mg
Vitamin B12 - 1500mg
Slow Fe - 180mg
12-28-2011, 03:57 AM   #2
Senior Member
Grumbletum's Avatar
Join Date: Dec 2010
Location: Western Isles, United Kingdom

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Hi Tom. I had a fair bit of nausea when I first started taking it but no D. Hope it works for you with no ill effects.
Dx Crohn's terminal ileum April 2011
Ileocaecal resection & partial cystectomy Sept 2012
3.5 years happy remission, in mild flare since Feb 2016 with related Portal Vein Thrombosis

Previous: Prednisolone, Mesren, Omeprazole, Infliximab, Azathioprine
Current: Pentasa, Librax, Warfarin
Helen x
02-05-2012, 09:44 AM   #3
Senior Member
NikiB's Avatar
Join Date: Feb 2012
Location: Burnaby British Columbia
I've been on 175mg of Azathioprine for 9 months now. Haven't experiences much side effects besides a bit of nausea if I don't eat enough before I take it. I have diarrhea less often and Im able to eat and drink stuff, like coffee without having to run to the bathroom.
02-05-2012, 10:11 AM   #4
Senior Member
Join Date: Aug 2011
Location: Southport
You could be have an reaction to aza and that is what happened contact your doctor or IBD nurse or it could be a side effect anyway I would contact them as soon as posible. Have you been having your bloods checked? and did you have a TPMT?? test sorry I always get the letter on this the wrong way round.
DX Small Bowel June 2011


Budesonise June 2011 - Sep 11
Aza Sep 2011- Nov 11
6MP Nov 11- Nov 11
Pred Nov 11 on going
MTX Jan 12 ongoing
Folic Acid 5mg Jan 12
B12 Vit Tabs

Crohn's Disease Forum » Treatment » Imuran/Azathioprine/6-MP » Imuran/Azathioprine and Diarrhea
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