Hi, it seems just fine. I've taken my LDN after a beer or two and kept going for the night with no problems. I'm not sure if in the longterm it's a good idea to continually take LDN with alcohol, or not. It is such a low dose and I don't think endogenous opiod systems have anything to do with alcohol (a depressant).
In fact, I've seen some suggest taking a night off of LDN every month or so is possibly a good thing; however, these comments seemed like speculation. Their reasoning is that it's good to give your body a break so it doesn't become immune to its effects, as this has been reported in a small minority of LDNers.