Crohn's Disease Forum » Treatment » Humira/Adalimumab » Regular poo AND the big D on Humira?

03-05-2012, 10:09 PM   #1
Miss Gypsy
Join Date: Jan 2012
Location: Washington, DC
Regular poo AND the big D on Humira?

Hey all!

Alert: poo discussion! So I've been on Humira for almost 3 months now. Overall it seems to be doing its job pretty nicely. I feel best the first few days after an injection: 1-2 BM per day, all normal. But the rest of the time between doses I have a bizarre mix - I tend to have a nice regular BM, but then 20-30 min later I'm back in the bathroom with 1-3 rounds of the big D. Granted, this is an improvement over what my symptoms were before, but I have no idea why my body can have regular poo and D at the same time. Has anyone else experienced this? Did you get better over time, live with it, increase your dose? Just want some input. Thanks!
Diagnosed April 2010, age 22
Previous Meds: Pentasa, Entocort, Remicade
Current Meds: Cipro and Flagyl

After 2 years, Humira has failed me - 2 abscesses in 2 months! Surgery sometime in November.
03-05-2012, 10:45 PM   #2
Forum Monitor
Trysha's Avatar
Join Date: Aug 2009

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Hello Miss Gypsy
You may find some information in the Humira section of the forum.
I have not had humira, but I am sure someone who has or is having treatment now with it, will be along soon to help with your question.
It may be a question to ask your GI.
Have you noticed any connection with your diet?
Feel better soon
Hugs and best wishes
03-06-2012, 08:00 AM   #3
suschex's Avatar
Join Date: Oct 2011
Location: Texas

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A few things to consider...

Humira can take a full 12 weeks to begin working and longer to be fully effective. I take bi-weekly shots as well but know many people on the forum take weekly shots. At times others have found greater success with adding additional meds to the Humira as prescribed by their GI.

I feel your frustration. I have been on Humira since mid November and reached remission only to come down with Strep that took 3 rounds of antibiotics that then turned into an upper respiratory infection. I had to go 6 weeks between Humira doses (can't take Humira with an active infection) and that allowed a bit of a flare.

Hang in there and call your GI!!!! This can be a frustrating time but there is help!
Crohn's Disease - October 10, 2011

Current Meds

Past Meds
03-10-2012, 12:01 AM   #4
Miss Underestimated
Senior Member
Miss Underestimated's Avatar
Join Date: Mar 2011
Location: Norfolk, Virginia
Yes. Mixture here. I'm beginning my 3rd month on Humira. I take Welchol and still have one solid BM and then 1-2 liquid. I've been taking imodium after the 3rd BM or if I have to go out.
*Sick since 1987; managed on my own;
*diagnosed 2008 when I underwent emergency surgery;
*various meds and tests 2008-2012,
*Jan 2012-present, Humira. No symptoms, but scopes indicated disease.
*6MP for all of 2013.
*2014 &2015 complete mucosal healing.

**Staying on Humira for maintenance**

The statistics I see so far for my situation seem pretty good. There ARE long term statistics for the Anti-TNF drug treatments now. I'm here to make them longER.

Crohn's Disease Forum » Treatment » Humira/Adalimumab » Regular poo AND the big D on Humira?
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