My wife was diagnosed in Jan with severe CD in the illium after having pain for two months. She has no D, just the pain. She has been on predisone and 1000mg pentassa 3xday, but every time she tappers the predisone to 10mg the pain returns and then she has to go back up to 15mg and start again. She is also following the SCD diet since Jan 100% without cheating. We have a appoitment with a wellness clinc in Mass. that will prescribe her LDN. My question is how long will it take for LDN to reduce the inflammation? Will she notice a decrease in pain after being LDN? Can you take LDN with predisone?