Crohn's Disease Forum » Treatment » Methotrexate » Immune-suppressents and Immune Increasing Vitamins

01-20-2014, 10:02 AM   #1
Cozmo's Avatar
Join Date: Nov 2012
Location: Llanidloes, United Kingdom

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Immune-suppressents and Immune Increasing Vitamins

I've just started Methotrexate. I've been taking 2000-4000mg of Vitamin C over the last year or two to help boost my immune system. Will it defeat the purpose of the immuno-supressents if I keep on taking the Vitamin C? Should I just stop taking the Vitamin C for the methotrexate to have it's full effect? Is there anyone else who has had a similar situation in regards to immune-suppressents and Vitamins? I'll continue to have my B12 injections and sometimes Iron due to my deficiency. Any help or suggestions are greatly appreciated
Diagnosed Crohns Nov 15th 2012
Prednisolone 30mg a day (6x 5mg)
Pentasa/Mesalazine 2 x 500mg 4 x a day
Azathpioprine 2 x 50mg a day(stopped after bad reaction)
Alendronic Acid 1 x weekly
Calceos 2 x a day
Diagnosed Gastronitis 2004
Lansaprazole 15mg a day
Diagnosed Aneamic 2011
B12 Injection every 3 months
Iron Tablets 3 x a day
Vitamin C Disolvable Effervessent 1000-2000mg a day
Diagnosed Aortitis May 23rd 2013
Ertapenam IV Antibiotic
01-20-2014, 10:51 AM   #2
nogutsnoglory's Avatar
Join Date: Sep 2009
Location: New York

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It's a question I have been asking doctors and experts at various forums for years and there is no consensus. I have heard the argument that because of our suppression of specific aspects of our immune system ie: TNF production that boosting the immune system as a whole is beneficial. The flip side argument is that we are decreasing an over active immune system and that these supplements are counterproductive.

I have never been given a rationale explanation that gives me confidence in either philosophy. My personal approach is to take immune boosting supplements with caution and at low doses. I'd much prefer to focus on immune boosting foods that don't have the high quantities to cause too much imbalance yet are good overall.

Crohn's Disease Forum » Treatment » Methotrexate » Immune-suppressents and Immune Increasing Vitamins
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