Hi all,
I am a long time lurker and first time poster. I was just wondering if anyone on remicade or any biologics for that matter have had any problems with high liver enzymes. I have noticed a lot of people post on this, but my situation seems a bit different. All of my liver enzymes are ok except for my bilirubin. I got a further test and my indirect billirubin is high 2.2(reference 1.2) all else is good (direct,ast,alt,alk). I was on asacol and remicade but have been off asacol for around two months. i have had consistent high bilirubin levels over the past 4-5 months,2.5,1.8,2.2 and 2.2 (been on remicade for 10mths). we suspected it might be the asacol but since i have been off of it for a while we assume it is the remicade. I was just curious as to if any one else had this problem. I had three hypothesis as to why it might be high, 1) it just the remicade and i cant do anything about it but hope my body adjust. 2) i run 2 miles 4 times a week, could this put too much strain on it? I had read about how strenous exercise could raise levels, but that was mostly in weight training, not aerobic exercise. 3) I smoke marijuana 1-2 times on the weekends to unwind (use to be beer but thats not good for my UC). I will probably eliminate the MJ before my next test to see if it has any effect, but in the mean time i just figured i could see if anyone has had similar circumstances. doc said if bilirubin gets to above 3 we will have to do a liver biopsy. If it is the remicade we will have to switch to something else. Mostly i am just trying to make sure that i am not adding to the problem. Thanks all
I am a long time lurker and first time poster. I was just wondering if anyone on remicade or any biologics for that matter have had any problems with high liver enzymes. I have noticed a lot of people post on this, but my situation seems a bit different. All of my liver enzymes are ok except for my bilirubin. I got a further test and my indirect billirubin is high 2.2(reference 1.2) all else is good (direct,ast,alt,alk). I was on asacol and remicade but have been off asacol for around two months. i have had consistent high bilirubin levels over the past 4-5 months,2.5,1.8,2.2 and 2.2 (been on remicade for 10mths). we suspected it might be the asacol but since i have been off of it for a while we assume it is the remicade. I was just curious as to if any one else had this problem. I had three hypothesis as to why it might be high, 1) it just the remicade and i cant do anything about it but hope my body adjust. 2) i run 2 miles 4 times a week, could this put too much strain on it? I had read about how strenous exercise could raise levels, but that was mostly in weight training, not aerobic exercise. 3) I smoke marijuana 1-2 times on the weekends to unwind (use to be beer but thats not good for my UC). I will probably eliminate the MJ before my next test to see if it has any effect, but in the mean time i just figured i could see if anyone has had similar circumstances. doc said if bilirubin gets to above 3 we will have to do a liver biopsy. If it is the remicade we will have to switch to something else. Mostly i am just trying to make sure that i am not adding to the problem. Thanks all