Crohn's Disease Forum » Books, Multimedia, Research & News » First Trial of Bioelectronic Device to control CD

12-05-2014, 08:23 AM   #1
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First Trial of Bioelectronic Device to control CD

"SetPoint’s novel platform consists of an implantable miniature neuromodulation device, wireless charger and iPad prescription pad application. The system uses vagus nerve stimulation to activate the body’s natural Inflammatory Reflex, which produces a potent systemic anti-inflammatory effect."

This technology has been shown effective in limited studies for RA and now being investigated for CD.

If this pans out, we'll one day have an App for controlling CD! What a trip.
12-05-2014, 08:47 AM   #2
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Location: Cambridge, United Kingdom
That's really interesting, thanks for posting!
Symptoms from the age of 12. Mis-diagnosed with UC at the age of 13, and later diagnosed with Crohn's in January 2012 at 24 years old. Disease mainly in terminal ileum.

Current meds:
Azathioprine, Allopurinol, Calcichew D3-Forte, Fortijuice, Alendronic acid, Ranitidine

Previous meds:
Augmentin, Doxycycline, Lansoprazole, Asacol, Pentasa, Prednisolone, Entocort, Cipro, Flagyl, Elemental Extra 028
12-05-2014, 09:47 AM   #3
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Location: New York

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Oh wow!

30 plus years and counting with UC/Crohn's!
on remicade since 11/05

While my experiences may not be what everyone has had- I feel it is worthwhile to share any and all experiences that may be beneficial to others.
12-05-2014, 10:31 AM   #4
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Location: Boise, Idaho

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That's pretty cool. Thanks for posting

Mom to Jack (18) dx Crohn's 2/2010
Remicade - started 1/9/14; 7.5ml/kg every 6 weeks
Past meds: Imuran/Azathioprine; allopurinol; methotrexate; LDN; Prednisone; Apriso; Pentasa; EEN

Husband dx Crohn's 3/1993
currently none due to liver issues
12-05-2014, 11:04 AM   #5
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Wow that's crazy. I guess there IS an app for everything haha.

Have you synced your bowel to your phone lol?
12-23-2014, 09:23 PM   #6
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There may be something to this whole notion of peripheral neuromodulation to control IBD. DARPA, the folks who brought us the Internet, is pursuing this as a form of self-healing therapy. There are so many frontiers being explored to tackle this disease.
12-24-2014, 07:52 AM   #7
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I am not sure if it is connected or not but yesterday in the UK there was a news story about electrical implants for rheumatoid arthritis that work directly in our nervous system to control inflammation. Bearing in mind that a lot of our current treatments have come from RA based options, you never know.......

Here is a link to the story if you are interested

DX - June 2012 with mild/moderate Crohns. In July 2012 bowel perforated unexpectedly and needed emergency surgery.
Current meds/supplements - Stelara (Nov 2017), Budesonide (when required), B12 injections (every 10 wks), Vit D tabs 800iu x daily, Ferrous Sulphate 200mg every day, Folic Acid once a week
Previous meds - Allergic to Azathioprine, 6MP, Pentasa & Asacol, Methotrexate injections (didn't work). Stopped Humira after 2 years due to ineffectiveness.
12-25-2014, 07:07 PM   #8
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Join Date: Feb 2006
Location: Naples, Florida
This is extremely interesting to me. As I have postulated before, I suspect one of the potential causes of some forms of Crohn's disease to be chronic pesticide exposure, especially organophosphates and carbamates. Each of these families of pesticides are shown to have a negative affect on the vagus nerve. That stimulating the vagus nerve is hypothesized to have a beneficial affect on inflammation would reinforce my theory.
It's good to be back
12-26-2014, 06:12 AM   #9
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You should get in contact w the researchers David
-Are you looking for a new treatment option for your Crohn's disease? If so, I suggest you look into the ongoing clinical trial by Qu Biologics for their SSI treatment. Click here for more information or to help spread the word.

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