Crohn's Disease Forum » Pregnancy, Trying to Conceive & Breast Feeding with IBD » Purinethol/Mercaptopurine and pregnancy...halp!!!

06-10-2016, 04:38 PM   #1
Mellybean's Avatar
Join Date: Apr 2014
Location: Backwoods Canada
Purinethol/Mercaptopurine and pregnancy...halp!!!

Okay so following my trip to the ER, I've been hospitalised since Tuesday. Had many many discussions with my awesome, amazing and very knowledgeable doctor about treatment. At the moment, we agreed to keep taking purinethol as long as necessary and stop the medication as soon as my condition will allow. I am however extremely worried. It is a cytotoxic medication with risks involved. I don't want to Google too much of it, lest I drive myself nuts. Any moms out there with experience with immune suppressors and pregnancy? How did it go for you??
06-11-2016, 12:25 AM   #2
Senior Member
FrozenGirl's Avatar
Not sure if you have seen it but check out his thread:

Since 6-mp is what azathioprine is converted to in the body the responses will be applicable to you.
Dx: Ulcerative Colitis, Nov 2013
Currently on:
Mezavant 4.8g
Vitamin D 1000iu
Tecta 40mg
Remicade: 600mg, every 4 weeks
Methotrexate: 15 mg (injection)
06-14-2016, 06:34 AM   #3
Jennifer's Avatar
The main thing is for you to be healthy. Poor health and malnutrition etc can have devastating effects on the baby. 6MP is a class C drug meaning that there are possible risks (drugs that are category D or X should be completely avoided during pregnancy) but untreated disease also has risks. Many members have had healthy babies while on 6MP during pregnancy (I cannot recall a member ever saying that it caused any damage to the baby since I joined in 2010). I take it as well and have been trying to conceive but no luck yet. My GI wants me to stay on 6MP if I do become pregnant. The only doctors I've spoken to who said I should stop it aren't very knowledgeable about Crohn's. In the end it's your decision but just remember that your health is the key to a healthy baby. Congratulations on your pregnancy.
Diagnosis: Crohn's in 1991 at age 9
Surgeries: 1 Small Bowel Resection in 1999; Central IV in 1991-92
Meds for CD: 6MP 75mg
Things I take: Tenormin 25mg (PVCs and Tachycardia), Junel (endometriosis), Tylenol 3 (Osteoarthritis), Zantac 150mg 2/day (acid reflux), Klonopin 1mg (Panic Disorder), Imitrex 25mg (migraines), Zofran 8mg (nausea)
Currently in: REMISSION Thought it was a flare but it's just scar tissue from my resection. Dealing with a stricture. Remission from my resection, 19 years and counting.

Crohn's Disease Forum » Pregnancy, Trying to Conceive & Breast Feeding with IBD » Purinethol/Mercaptopurine and pregnancy...halp!!!
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