6mp

Hi...this is my first time using this, so Im sorry if it's strange or whatever. I have crohns disease and was diagnosed in April this year. Im on budeisonode and starting metacaptopurine, which brings me to my question. I'm am so nervous and scared about 6mp as azathioprine made me very very unwell and sick all the time! Does 6mp do the same? What we're your experiences of 6mp, do you have any tips or advice?? I appreciate any responses! Thank you

6mp and Aza are very closely related
Ds failed 6-mp -went to his liver
We were told Aza would probably do the same since it was closely related
After ds failed 6-mp he was switched to mtx

Is methotrexate (mtx ) an option ???

my little penguin said:

6mp and Aza are very closely related
Ds failed 6-mp -went to his liver
We were told Aza would probably do the same since it was closely related
After ds failed 6-mp he was switched to mtx

Is methotrexate (mtx ) an option ???

Click to expand...

I've only been offer aza and 6mp so far but docs are hoping this will finally put me into remission! I am so concerned about all of the side affects especially the vomiting. I'll look into it and ask my consultant. Thankyou

If you had severe side effects with Aza
I would try to ask about mtx

Hi, my daughter is 20 years old and has been on 6MP for the past 8 years! The first few weeks she did have some hair loss but nothing major. She's still taking it without any side effects. I hope you feel better soon!

I took my fist dose last night...woken up with nausea and diarrhoea which isn't good! Hoping the antisickness kicks in soon! Thankyou for the replies it has helped!!

I've been on Entocort for a while, but was hospitalized--again--last March. My GI switched me to 6MP because I was on Entocort when everything went south again. Naturally I developed pancreatitis from the 6MP (some people do). That ruled out both 6MP and Imuran (per my GI) since the latter is a prodrug of the former. I am surprised your GI is giving you 6MP after all your side effects with Imuran.

One thing I have learned, though, is that gastroenterologists often disagree with one another. My GP sent me to an IBD specialist who disagreed with everything my GI diagnosed (celiac disease and small bowel crohn's) because "there is never mucosal healing with either illness". My regular GI just looked at me and asked if the specialist had any ideas about what I did have. When I replied "no" he chuckled and said that was what he thought! So I am back on Entocort but have developed a narrowing and adhesion at the terminal ileum. The next step in treatment will be Humira but my GI wants to see if the Entocort will help resolve things first.

Jabee
The new school of thought is to have clinical remission (all bloodwork looks good ) -and mucosal healing - it is possible and a lot of crohns patients have it either with immunosuppressants or biologics or both
Ds last scope looked pristine

Good luck

Thanks, MLP. GIs seem to want a "solid tissue diagnosis"; that's hard to get when the disease is in the small bowel. My regular GI has scoped me numerous times (both for the celiac diagnosis and three years later after a bone marrow biopsy showed I had no iron left in my body). At that time there was severe duodenal ulceration and a stricture in the same area. More recently the crohn's has been active in my jejunum and ileum (nice skip pattern, too), but seen mostly on CT scan because my pillcams have been after I've been on prednisone for a few months, and of course without any biopsies. It was strange that the other GI I saw was so insistent on no mucosal healing, since that's what my regular guy wants; he was quite a bit older, though, so perhaps it was because he was using older standards--I hadn't thought of that.

Hope everything is fine with your son.