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Angular Cheilitis

Angular Cheilitis, also known as Angular Stomatitis, is a lesion at the corner of the mouth that is commonly caused by various B vitamin (and sometimes iron) deficiencies in people with Crohn's Disease.[1][2]



Presenting This Information to your Doctor

Not all doctors are aware that Angular Stomatitis can be caused by Vitamin and Mineral Deficiencies. We can't expect our doctors to know everything and the key is to present reputable material to them in a supportive manner so they can learn along with us. For this condition, we suggest printing out this paper and highlighting the following:
For patients not responding to simple therapeutic measures, the next appropriate step is to arrange full hematological screening with measurements of hemoglobin, mean corpuscular volume, folate, vitamin B2, vitamin B6, vitamin B12, serum iron, ferritin, transferrin, and fasting blood glucose. Nutritional deficiencies, especially of iron and B vitamins, are important in the development of angular cheilitis.


If a B vitamin deficiency is found to be present, sometimes an oral complex B vitamin or the specific B vitamin(s) can be supplemented. Occasionally, due to malabsorption issues, injections may be necessary. If the cause is found to be iron deficiency, then treatment would be the same as for anemia. It is important that vitamin and mineral levels be monitored in people with Crohn's Disease to ensure optimum levels are being maintained.


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