About Asacol

Asacol (active ingredient Mesalamine) is an Orally Administered Anti-Inflammatory preparation designed to treat Inflammation in the large intestine. It is coated with a pH-sensitive acrylic polymer and releases 5-ASA in the terminal ileum and colon at pH of 7.0.[1]

Approximately 28% of Mesalamine is absorbed after oral dosing. The balance is left for topical activity on the mucosa of the Gastrointestinal tract.

Asacol is approved for use in mild to moderate Ulcerative Colitis. Its use in Crohn's Disease is "off label" and efficacy has not been proven. It is thought that mesalamine acts topically and as Crohn's Disease is transmural, it may not be treating the full extent of the disease.

Passing Whole Asacol Tablets

Approximately 2-3% of patients will pass Asacol tablets whole. When this occurs, your physician should be notified. If you're feeling brave, fishing out the pill to determine if the medication was released or not is useful.

Side Effects

- Approximately 3% of people taking Asacol will experience a worsening of symptoms and a physician should be immediately notified.
- Dizziness
- Nausea
- Joint Pain
- Rash
- Indigestion
- Muscle Cramps
- Dry Mouth
- Headache

Pregnancy Category

- Asacol is pregnancy category C.


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