Crohn's Disease Forum » Forum Wiki » Scleroderma



Scleroderma is an autoimmune disease of the connective tissues and causes abnormal deposits of Collagen protein under the skin.

There are two types of Scleroderma: Limited Scleroderma (CREST Syndrome), and Diffuse Scleroderma. Scleroderma can affect the skin, joints, muscles, lungs, blood vessels, and GI Tract.

Scleroderma can cause the skin to become abnormally hard and may result in immobility, skin may become discolored, or produce ulcers (sores), or white lumps under the skin. Reactions of the skin (and blood vessels) such as Raynaudís Phenomenon can occur as well.

Scleroderma can be painful or cause numbness in affected areas.

The joints may become stiff, swollen and painful. Scleroderma can affect the GI Tract motility and nutritional absorbtion and can affect lung function due to fibrotic tissue buildup in the lungs.

Other autoimmune diseases can occur with Scleroderma as well. Mixed Connective Tissue Disease may be diagnosed if Scleroderma occurs with other autoimmune diseases such as SLE (Systemic Lupus Erythematosus) and Polymyositis (autoimmune disease of skeletal muscle).


1. Scleroderma. (2012) A.D.A.M.

Popular Threads Discussing Scleroderma

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04-25-2012, 04:29 PM   #1
Senior Member
CLynn's Avatar
Join Date: Feb 2012
Location: Missouri
Thanks, Judith! I have a good friend who's mother has this, have always wondered what it was.
Previous meds: Sulfadiazine, Flagyl, Prednisone, Imuran, Pentasa, Asacol
Surgeries: re-section 2004
Currently taking: B-12 injections every 2 weeks, multi vitamin/mineral, fish oil (1000 mg), D3 (5000 mg)

Also lucky enough to have psoriasis as well.
04-25-2012, 05:11 PM   #2
Senior Member
Josephine's Avatar
Join Date: Jan 2011
Location: Middlesbrough
Hmm sound very interest and familiar in signs.
Acid Reflux for 15 years med

Sacroiliitis and add to grew list auto immune diseases.

Now on Lansprazole 15 mg And Gavin son 5mg-10mg 3a day.

Crohns from Oct 2007
Domperidone 10 mg -20 mg, Mebeverine 135 mg,
3 a day.
Balsalazide 750 mg 3 X3 a day on going.
Bone protection.

Azathioprine is not working, still waiting to find out what next. Still on low dosage Prednisolone

Mesalamine Enema

No Wheat

English my native language and have characterizes of dyslexia.
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